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COX 4 - 298 003

A protein of the inner mitochondrial membrane
Polyclonal rabbit purified antibody
Cat. No.: 298 003
Amount: 50 µg
Price: 450.00 €
Cat. No. 298 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 1 to 18 from mouse COX4 (UniProt Id: P19783)
Reactivity Reacts with: rat (P10888), mouse (P13073).
Other species not tested yet.
Specificity Specific for COX 4.
Matching control protein/peptide 298-0P
Data sheet 298_003.pdf

References for COX 4 - 298 003

Hippocampal Subregions Express Distinct Dendritic Transcriptomes that Reveal Differences in Mitochondrial Function in CA2.
Farris S, Ward JM, Carstens KE, Samadi M, Wang Y, Dudek SM
Cell reports (2019) 292: 522-539.e6. 298 003 IHC; tested species: mouse
Cat. No.: 298 003
Quantity: 50 µg
Price: 450.00 €
Hippocampal Subregions Express Distinct Dendritic Transcriptomes that Reveal Differences in Mitochondrial Function in CA2.
Farris S, Ward JM, Carstens KE, Samadi M, Wang Y, Dudek SM
Cell reports (2019) 292: 522-539.e6. 298 003 IHC; tested species: mouse
Background
The enzyme cytochrome C oxidase or Complex 4 is a large heterooligomeric enzyme consisting of 13 subunits. It is localized to the inner mitochondrial membrane. It catalyzes the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane. The resulting proton gradient finaly drives ATP synthesis.