Home|||||||Technical Support|

GABA transporter 3 antibody - 274 302

GATs are neurotransmitter transporters involved in the termination of GABA transmission
Polyclonal rabbit antiserum
Cat. No.: 274 302
Amount: 200 µl
Price: $350.00
Cat. No. 274 302 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 612 to 627 from mouse GABA transporter3 (UniProt Id: P31650)
Reactivity Reacts with: rat (P31647), mouse (P31650).
Other species not tested yet.
Specificity Specific for GAT 3.
Matching control protein/peptide 274-3P
Remarks

WB:  GABA transporter 3 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

Data sheet 274_302.pdf
Cat. No.: 274 302
Quantity: 200 µl
Price: $350.00
Background
γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. After the release of GABA from synaptic vesicles into the synaptic cleft during neurotransmission, GABA transporters (GATs) remove extracellular GABA by reuptake into the presynaptic terminal.
Three GABA transporters are described so far of which only GAT 1 and GAT 3 are expressed in the brain.