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CNGA3 antibody - 267 003

CNGA3 is a cyclic nucleotide-gated channel
Rabbit polyclonal purified antibody
Cat. No.: 267 003
Amount: 50 µg
Price: $370.00
Cat. No. 267 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 5000 gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 653 to 670 from rat CNGA3 (UniProt Id: Q9ER33)
Reactivity Reacts with: rat (Q9ER33), mouse (Q9JJZ8).
Other species not tested yet.
Specificity Specific for CNGA3. K.O.
Data sheet 267_003.pdf
Cat. No.: 267 003
Amount: 50 µg
Price: $370.00
Background
In the mammalian retina two types of photoreceptors, rods and cones, occur. Their response to light is mediated by the closure of a cyclic nucleotide-gated (CNG) cation channel in the plasma membrane, causing hyperpolarization and a decrease of glutamate release.
In rods the CNG channel is formed by the subunits CNGA1 and CNGB1 and in cones by CNGA3 and CNGB3. Accordingly CNGA3 knockout mice lack any cone-mediated photoresponse.
This antibody is a useful marker for photoreceptors.