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NET antibody - 260 308

The NE transporter is involved in the termination of synaptic transmission
Guinea pig monoclonal recombinant IgG
Cat. No.: 260 308
Amount: 50 µg
Price: $415.00
Cat. No. 260 308 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 1000 up to 1 : 2000 gallery  
IHC-P: not tested yet
Clone Gp215A9
Subtype IgG2 (κ light chain)
Immunogen Synthetic peptide corresponding to residues surrounding AA 200 of rat NET. (UniProt Id: Q63380)
Reactivity Reacts with: rat (Q63380), mouse (O55192).
Other species not tested yet.
Specificity Specific for NET.
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 215A9. The constant regions of the heavy and light chains have been replaced by Guinea pig specific sequences. Therefore, the antibody can be used with standard anti-Guinea pig secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 260_308.pdf
Cat. No.: 260 308
Amount: 50 µg
Price: $415.00
Background
The norepinephrine (NE) transporter (NET), also referred to as Sodium-dependent noradrenaline transporter, is expressed on the plasma membranes of noradrenergic neurons. It is responsible for the inactivation of synaptically released NE and is a target for many antidepressants and psychostimulants.