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Cannabinoid receptor CB1-R antibody - 258 009

CB1-R is a G-protein coupled receptor responsive to cannabinoids
Chicken monoclonal recombinant IgY
Cat. No.: 258 009
Amount: 50 µg
Price: $415.00
Cat. No. 258 009 50 µg purified recombinant IgY, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Clone Ch289C1
Subtype IgY (λ light chain)
Immunogen Synthetic peptide corresponding to AA 450 to 473 from rat CB1-R (UniProt Id: P20272)
Reactivity Reacts with: rat (P20272), mouse (P47746), human (P21554).
Other species not tested yet.
Specificity Specific for CB1-R. K.O.
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 289C1. The constant regions of the heavy and light chains have been replaced by chicken specific sequences. Therefore, the antibody can be used with standard anti-chicken secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 258_009.pdf
Cat. No.: 258 009
Amount: 50 µg
Price: $415.00
Background
The cannabinoid receptor CB1-R is a G-protein coupled receptor (GPCR) with 7 transmembrane domains. It is responsive to tetrahydrocannabinol, the psychotropic component of marijuana.
Endogenous cannabinoids (endocannabinoids) are released from postsynaptic neurons and act onto presynaptic cannabinoid receptors where they play important physiological roles in synaptic plasticity, analgesia, appetite, and neuroprotection.