Synaptic Systems

Cat. No.: 248 003

Amount: 50 µg

Price: $380.00

Cat. No. 248 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 gallery IP: not tested yet ICC: 1 : 200 up to 1 : 500 gallery IHC: 1 : 100 gallery IHC-P: not tested yet DNA-PAINT: yes (see remarks)
Immunogen	Recombinant protein corresponding to AA 1 to 266 from rat Mover (UniProt Id: A8WCF8)
Reactivity	Reacts with: rat (A8WCF8), mouse (Q9DBS2). Other species not tested yet.
Specificity	Specific for mover. Shows some cross-reactivity to Ribeye K.O. validated PubMed: 31787876
Remarks	DNA-PAINT: This antibody has been successfully used for DNA-PAINT application (see Unterauer et al., 2024; PMID: 38552614).
Data sheet	248_003.pdf

The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting.
Akula AK, Zhang X, Viotti JS, Nestvogel D, Rhee JS, Ebrecht R, Reim K, Wouters F, Liepold T, Jahn O, Bogeski I, et al.
Frontiers in molecular neuroscience (2019) 12: 249. 248 003 WB, ICC; KO verified; tested species: mouse

Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover.
Körber C, Horstmann H, Venkataramani V, Herrmannsdörfer F, Kremer T, Kaiser M, Schwenger DB, Ahmed S, Dean C, Dresbach T, Kuner T, et al.
Neuron (2015) 873: 521-33. 248 003 WB, IHC; KD verified

Cat. No.: 248 003

Amount: 50 µg

Price: $380.00

ICC

IHC

Background

Protocols

Mover antibody - 248 003 K.O.