Cat. No.: 244 115
Amount: 50 µg
Price:
$460.00
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| Cat. No. 244 115 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not recommended IHC: not recommended IHC-P: not tested yet |
| Immunogen | Recombinant protein corresponding to AA 918 to 1470 from rat GluN2B (UniProt Id: Q00960) |
| Reactivity |
Reacts with: rat (Q00960), mouse (Q01097). Other species not tested yet. |
| Specificity | Specific for GluN 2B, no cross-reactivity to GluN 2A. |
| Data sheet | 244_115.pdf |
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GluNs (NMDA-receptors) represent a class of glutamate receptors that are of central importance in synaptic plasticity. Multiple NMDA receptor subtypes exist: GluN 1 and GluN 2 A-D. GluN 1 is the most important as it is required for activity. NMDA-receptors allow Ca2+ influx and are thought to trigger Ca2+ dependent postsynaptic processes involved in long term potentiation and depression.