Synaptic Systems

Cat. No.: 242 003

Amount: 50 µg

Price: $380.00

Cat. No. 242 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 (AP staining) gallery IP: yes ICC: 1 : 500 gallery IHC: 1 : 200 up to 1 : 500 gallery IHC-P: not tested yet EM: yes
Immunogen	Synthetic peptide corresponding to AA 567 to 585 from mouse Kv3.1b (UniProt Id: P15388)
Reactivity	Reacts with: human (P48547), rat (P25122), mouse (P15388), cow. No signal: zebrafish. Other species not tested yet.
Specificity	K.O. validated PubMed: 35510987
Matching control protein/peptide	242-0P
Data sheet	242_003.pdf

HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex.
Szegedi V, Bakos E, Furdan S, Kovács BH, Varga D, Erdélyi M, Barzó P, Szücs A, Tamás G, Lamsa K
PLoS biology (2023) 212: e3002001. 242 003 IHC; tested species: human,mouse

Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse.
Richardson A, Ciampani V, Stancu M, Bondarenko K, Newton S, Steinert JR, Pilati N, Graham BP, Kopp-Scheinpflug C, Forsythe ID
eLife (2022) 11: . 242 003 IHC; KO verified; tested species: mouse

A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses.
Holderith N, Heredi J, Kis V, Nusser Z
Cell reports (2020) 324: 107968. 242 003 IHC; tested species: rat

Cat. No.: 242 003

Amount: 50 µg

Price: $380.00

ICC

IHC

Background

Protocols

Kv3.1b antibody - 242 003 K.O.