Tailor-made Antibodies
and Tools for Life Science

GABA-A receptor gamma2 antibody extracellular - 224 011

GABA-A receptors are involved in inhibitory neurotransmission
Mouse monoclonal purified IgG
Cat. No.: 224 011
Amount: 100 µg
Price: $420.00
Cat. No. 224 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: yes
ICC: 1 : 500 (see remarks) gallery  
IHC: 1 : 500 (see remarks) gallery  
IHC-P: not tested yet
EM: yes
Clone 331A12
Subtype IgG2a (κ light chain)
Immunogen Synthetic peptide corresponding to AA 39 to 67 from mouse GABA-A receptor γ2 (UniProt Id: P22723)
Reactivity Reacts with: human (P18507), rat (P18508), mouse (P22723).
Other species not tested yet.
Specificity Specific for GABA-A receptor γ2. Does not discriminate between the L and S form.
Matching control protein/peptide 224-0P
Remarks

ICC: This antibody is also suitable for the surface staining of living cells. After washing cells with bound antibodies, they can be fixed and visualized with secondary reagents.
IHC: This antibody requires mild fixation.

Data sheet 224_011.pdf

References for GABA-A receptor gamma2 - 224 011

The TMEM132B-GABAA receptor complex controls alcohol actions in the brain.
Wang G, Peng S, Reyes Mendez M, Keramidas A, Castellano D, Wu K, Han W, Tian Q, Dong L, Li Y, Lu W, et al.
Cell (2024) 18723: 6649-6668.e35. 224 011 ICC; tested species: mouse
Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.
Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, et al.
Cell (2018) 1733: 735-748.e15. 224 011 ICC; tested species: mouse
Cat. No.: 224 011
Amount: 100 µg
Price: $420.00