Tailor-made Antibodies
and Tools for Life Science

Abeta42 antibody - 218 703

Abeta peptides are major components of neuritic plaques in Alzheimer's disease
Rabbit polyclonal purified antibody
Cat. No.: 218 703
Amount: 50 µg
Price: $385.00
Cat. No. 218 703 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (ECL detection) (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 100 up to 1 : 500 (see remarks) gallery  
IHC-P: 1 : 100 (see remarks) gallery  
ELISA: yes suitable only as capture antibody, cat. no. 218 211 is recommended detector antibody for gallery  
Immunogen Synthetic peptide corresponding to AA 37 to 42 from human Abeta42 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067), rat (P08592), mouse (P12023).
Other species not tested yet.
Specificity Specific for Abeta 42 with weak cross-reactivity to Abeta 40 in westernblots that is not apparent in ELISA tests.
Remarks

WB: Detects purified Abeta 42. Complex samples like brain extracts still have to be tested. Nitrocellulose membrane is recommended for blotting. Boil membrane after blotting for 3min.
IHC: Antigen retrieval with formic acid is required.
IHC-P: Antigen retrieval with formic acid is required.

Data sheet 218_703.pdf

References for Abeta42 - 218 703

Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease.
Al-Atrache Z, Lopez DB, Hingley ST, Appelt DM
BMC neuroscience (2019) 201: 6. 218 703 ICC; tested species: human
Cat. No.: 218 703
Amount: 50 µg
Price: $385.00