Tailor-made Antibodies
and Tools for Life Science

Abeta38 antibody - 218 411

Abeta peptides are major components of neuritic plaques in Alzheimer's disease
Mouse monoclonal purified IgG
Cat. No.: 218 411
Amount: 100 µg
Price: $420.00
Cat. No. 218 411 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (see remarks) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 (see remarks) gallery  
IHC-P: 1 : 250 up to 1 : 2000 (see remarks) gallery  
ELISA: yes , suitable as detector and capture antibody . gallery  
Clone 67B8
Subtype IgG2a
Immunogen Synthetic peptide corresponding to AA 33 to 38 from human Abeta38 (UniProt Id: P05067)
Reactivity Reacts with: human (P05067).
Other species not tested yet.
Specificity Specific for Abeta 38
Remarks

WB: Detects specifically 1 ng of purified Abeta 38. Complex samples like brain extracts still have to be tested. Boil membrane after blotting for 3min.
IHC: Antigen retrieval with formic acid is required.
IHC-P: Antigen retrieval with formic acid is required.

Data sheet 218_411.pdf

References for Abeta38 - 218 411

A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor.
Liu L, Ding L, Rovere M, Wolfe MS, Selkoe DJ
The Journal of cell biology (2019) 2182: 644-663. 218 411 ELISA; tested species: human
Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life.
Liu L, Lauro BM, Ding L, Rovere M, Wolfe MS, Selkoe DJ
Alzheimer's & dementia : the journal of the Alzheimer's Association (2019) : . 218 411 ELISA; tested species: human
Cat. No.: 218 411
Amount: 100 µg
Price: $420.00