Tailor-made Antibodies
and Tools for Life Science

Tenascin-C antibody - 217 127

Tenascin-C is a multidomain adhesion molecule
Rat monoclonal hybridoma supernatant
Cat. No.: 217 127
Amount: 200 µl
Price: $365.00
Cat. No. 217 127 200 µl hybridoma supernatant, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 500 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: yes
IHC-P: 1 : 500 up to 1 : 1000 gallery  
Clone 578
Subtype IgG2a
Immunogen Recombinant protein corresponding to AA 23 to 2210 from mouse Tenascin-C (UniProt Id: Q80YX1)
Epitop AA 1082 to 1510 from mouse Tenascin-C (UniProt Id: Q80YX1)
Reactivity Reacts with: rat, mouse (Q80YX1).
Other species not tested yet.
Specificity Specific for tenascin-C splice variants carrying the FNIII D domain.
Remarks

Tenascin-C variants detected by this antibody are downregulated during development and hardly detectable in adult animals

Data sheet 217_127.pdf

References for Tenascin-C - 217 127

Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin.
Rigato F, Garwood J, Calco V, Heck N, Faivre-Sarrailh C, Faissner A
The Journal of neuroscience : the official journal of the Society for Neuroscience (2002) 2215: 6596-609. 217 127 WB
Expression of tenascin in the developing and adult cerebellar cortex.
Bartsch S, Bartsch U, Dörries U, Faissner A, Weller A, Ekblom P, Schachner M
The Journal of neuroscience : the official journal of the Society for Neuroscience (1992) 123: 736-49. 217 127 WB, IHC
Cat. No.: 217 127
Amount: 200 µl
Price: $365.00