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ChT - 216 004

A high affinity choline transporter
Polyclonal Guinea pig antiserum
Cat. No.: 216 004
Amount: 100 µl
Price: 350.00 €
Cat. No. 216 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: not recommended
IHC-P/FFPE: 1 : 200 up to 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 501 to 581 from rat ChT (UniProt Id: Q9JMD7)
Reactivity Reacts with: rat (Q9JMD7).
Weaker signal: mouse (Q8BGY9).
Other species not tested yet.
Specificity Specific for the high affinity choline transporter
Data sheet 216_004.pdf
Cat. No.: 216 004
Quantity: 100 µl
Price: 350.00 €
Background
Acetylcholine (ACh) functions as a neurotransmitter in both the central and peripheral nervous systems of all vertebrates, and is the principle neurotransmitter used at the neuromuscular junction. This neurotransmitter is synthesized from choline (Ch) and acetyl-coenzyme A by choline acetyltransferase (ChAT). For this pathway choline is required, which neurons acquire through high-affinity choline transporters (ChTs). ChT have been found on the presynaptic membrane but also on ACh containing synaptic vesicles.