|Cat. No. 214 011C3||
100 µg purified IgG, lyophilized, fluorescence-labeled with Oyster® 550
Fluorescence labeled antibodies conjugated to Oyster dyes from
Oyster dyes, Oyster-488, Oyster-500, Oyster-550, and Oyster-650 are trademarks of Luminartis GmbH, Muenster/Germany.
CyDyes, Cy2, Cy3, and Cy5 are trademarks of GE-Healthcare Ltd.
Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.The mounting agent Aquatex®(Merck Chemicals) is not compatible with Oyster dyes!
ICC: not tested yet
IHC: 1 : 200 gallery
IHC-P/FFPE: not tested yet
|Subtype||IgG1 (κ light chain)|
|Immunogen||Recombinant protein corresponding to AA 3 to 251 from human CalbindinD28k (UniProt Id: P05937)|
Epitop: AA 3 to 251 from human CalbindinD28k (UniProt Id: P05937)
Reacts with: human (P05937), rat (P07171), mouse (P12658), zebrafish.
Other species not tested yet.
|Specificity||Specific for calbindin D28k.|
|Matching control protein/peptide||214-0P|
Two isoforms of the vitamin D-dependent Ca-binding proteins have been described so far: calbindin D28k, also referred to as CALB 1, D-28k, and CAB 27, and calbindin D29k, also known as calretinin. These proteins are expressed in cells that have to handle a high calcium influx such as brain, bone, teeth, inner ear and others. Calbindins are believed to regulate cellular activity by suppressing or buffering intracellur calcium