Home|||||||Technical Support|

Cytohesin 3 - 212 303

A group of guanine nucleotide exchange factors (GEFs)
Polyclonal rabbit purified antibody
Cat. No.: 212 303
Amount: 50 µg
Price: $370.00
Cat. No. 212 303 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 70 from rat Cytohesin3 (UniProt Id: P97696)
Reactivity Reacts with: rat (P97696), mouse (O08967).
Other species not tested yet.
Specificity Specific for cytohesin 3.
Data sheet 212_303.pdf
Cat. No.: 212 303
Quantity: 50 µg
Price: $370.00
Background
Cytohesins are a group of guanine nucleotide exchange factors (GEFs) that contain an N-terminal coil, a central Sec-7 and a C-terminal pleckstrin homology (ph) domain.
They control the activity of ADP-ribosylation factors (Arfs) and are involved in the control of vesicular transport and organization of the actin cytoskeleton.
Cytohesins have also been reported to bind to integrins, a diverse family of heterodimeric transmembrane adhesion receptors that are present on most vertebrate cell types. These proteins are known to be involved in cell-cell or cell-matrix interactions.