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Cytohesin 1 - 212 103

A group of guanine nucleotide exchange factors (GEFs)
Polyclonal rabbit purified antibody
Cat. No.: 212 103
Amount: 50 µg
Price: $370.00
Cat. No. 212 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 66 from rat Cytohesin1 (UniProt Id: P97694)
Reactivity Reacts with: rat (P97694), mouse (Q9QX11).
Other species not tested yet.
Specificity Specific for cytohesin 1.
Data sheet 212_103.pdf
Cat. No.: 212 103
Quantity: 50 µg
Price: $370.00
Background
Cytohesins are a group of guanine nucleotide exchange factors (GEFs) that contain an N-terminal coil, a central Sec-7 and a C-terminal pleckstrin homology (ph) domain.
They control the activity of ADP-ribosylation factors (Arfs) and are involved in the control of vesicular transport and organization of the actin cytoskeleton.
Cytohesins have also been reported to bind to integrins, a diverse family of heterodimeric transmembrane adhesion receptors that are present on most vertebrate cell types. These proteins are known to be involved in cell-cell or cell-matrix interactions.