Synaptic Systems

Cat. No.: 202 003

Amount: 50 µg

Price: $480.00

Cat. No. 202 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	Dot blot: 1 : 1000 up to 1 : 10000 gallery IP: yes ICC: not tested yet IHC: not tested yet IHC-P (FFPE): not tested yet ELISA: suitable for sandwich-ELISA gallery MeRIP: yes Immunodetection of target molecules spotted onto a membrane. Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section. Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section. Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section. Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Enzyme-linked immunosorbent assay (ELISA); a frequently employed method to quantify target-molecules in solution. The detection of some proteins requires special solubilization steps. For further information, please refer to the „Remarks“ section. Methylated RNA immunoprecipitation (MeRIP) sequencing is an antibody based m6A-mapping method, based on parallel sequencing of immunoisolated RNA fragments (100 -200 nt long) carrying m6A modifications.
Immunogen	N6-methyladenosine fused to BSA
Reactivity	Reacts with: human, rat, mouse, eukaryotes, prokaryotes. Other species not tested yet.
Specificity	Specific for N6-methyladenosine (m6A) with some cross-reactivity to m6Am.
Data sheet	Datasheet 202_003

References for m6A - 202 003

Epstein-Barr virus suppresses N6-Methyladenosine modification of TLR9 to promote immune evasion.
Zhang X, Li Z, Peng Q, Liu C, Wu Y, Wen Y, Zheng R, Xu C, Tian J, Zheng X, Yan Q, et al.
The Journal of biological chemistry (2024) : 107226. 202 003 Dot blot, WB, MeRIP; tested species: human

METTL3-mediated m6A modification of circGLIS3 promotes prostate cancer progression and represents a potential target for ARSI therapy.
Cheng X, Yang H, Chen Y, Zeng Z, Liu Y, Zhou X, Zhang C, Xie A, Wang G
Cellular & molecular biology letters (2024) 291: 109. 202 003 WB, MeRIP; tested species: human

The methyltransferase METTL3 regulates endothelial cell proliferation and inflammation via m6A RNA methylation-mediated TRAF1 expression.
Chen D, Xu W, Zheng H, Zhang Y, Lin Y, Han Y, Yao F, Shen H
Biochemical and biophysical research communications (2024) 732: 150399. 202 003 WB, MeRIP; tested species: human

Immuno-Northern Blotting: Detection of Modified RNA Using Gel Separation and Antibodies to Modified Nucleosides.
Mishima E, Abe T
Methods in molecular biology (Clifton, N.J.) (2019) 1870: 179-187. 202 003 WB

HIV-1 envelope proteins up-regulate N6-methyladenosine levels of cellular RNA independently of viral replication.
Tirumuru N, Wu L
The Journal of biological chemistry (2019) : . 202 003 Dot blot, WB; tested species: human

Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides.
Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, et al.
PloS one (2015) 1011: e0143756. 202 003 Dot blot, WB

N6-methyladenine DNA Modification in Glioblastoma.
Xie Q, Wu TP, Gimple RC, Li Z, Prager BC, Wu Q, Yu Y, Wang P, Wang Y, Gorkin DU, Zhang C, et al.
Cell (2018) : . 202 003 Dot blot, IHC-P (FFPE), IP, ICC; tested species: human

RBM15 promotes hyperglycemia-induced retinal endothelial cell injury by regulating FOXO3 stability via m6A modification.
Yu Y, Ren Y, Dong S, Yao J, Chen Z
Molecular and cellular biochemistry (2026) : . 202 003 Dot blot, MeRIP; tested species: human

circ_0103896/miR-432-5p/FTO feedback loop suppresses the formation and progression of intracranial aneurysm.
Lu Z, Zhu S, Wu Y, Xu F, Huang Q
Non-coding RNA research (2026) 17: 59-75. 202 003 Dot blot; tested species: human

METTL14-mediated RNA m6A modifications of TET1 and TET2 in duck myoblast differentiation.
Liu J, Wu J, Liao Z, Wang Y, Xiao X, Chai X, Wei W, Liao W, Tang C, Hu X, Xu J, et al.
Poultry science (2026) 1053: 106435. 202 003 Dot blot

Epitranscriptomic Regulation of Platinum Resistance via the METTL3-ADAM23 Axis in Ovarian Cancer.
Kim U, Li J, Matei D, Huang H
Cells (2026) 153: . 202 003 Dot blot; tested species: human

Magnesium ions facilitate osteogenic differentiation and intervertebral fusion via m6A methylation of RhoA mRNA.
Xu H, Li L, Zhang F, Shao M, Li C, Xue Y, Li D, Lin Z, Gong Z, Wu J, Luo Z, et al.
Journal of orthopaedic translation (2026) 57: 101056. 202 003 Dot blot; tested species: mouse

Phytochrome B and the methyltransferase complex coordinately regulate N6-methyladenosine RNA modification and shade avoidance responses in Arabidopsis.
Li F, Zeng Y, Wang J, Li L
Plant communications (2026) : 101789. 202 003 Dot blot, MeRIP

Integrative Multi-Analysis Identifies METTL3-Regulated FGF19 and H6PD as Candidate Targets in Diabetic Cognitive Impairment.
Fu J, Wang H, Yan J, Chen W, Wang R, Gao H, Li C
Biomolecules (2026) 163: . 202 003 Dot blot, IHC; tested species: mouse

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3.
Li R, Wang X, Du W, Li Q, Cui HP
The Kaohsiung journal of medical sciences (2026) : e70194. 202 003 Dot blot; tested species: mouse

RBM15B-mediated m6A modification of FOXM1 activates the AURKA/TPX2 axis to promote epithelial-mesenchymal transition-driven endometrial cancer progression.
Zhang L, Wu P
Cell adhesion & migration (2026) 201: 2674357. 202 003 Dot blot, MeRIP; tested species: human

Xiayuxue decoction alleviates MASH by regulating gut microbiota, bile acid metabolism, and m6A modification.
Shi J, Zhao C, Zhang D, Zhang L, Feng Q, Qi S, He X, Liu P, Mu Y, Chen G, Ma W, et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology (2026) 154: 158023. 202 003 Dot blot, MeRIP; tested species: mouse

SlYTH3 regulates tomato leaf senescence via recognition of N6-methyladenosine-modified SlHDZIV2 transcripts.
Li M, Zhang X, Si X, Sun Y, Pan C, Lu G
The Plant cell (2026) 383: . 202 003 Dot blot, MeRIP

METTL3-m6A-LOXL2 Axis Post-Transcriptionally Fine-Tunes Macrophage Migration and Invasion.
Li Z, Sa XH, Han YW, Wang P, Song XY, Sun MX
Current medical science (2026) : . 202 003 Dot blot; tested species: human

ALKBH5 aggravates scarring after glaucoma surgery via m6A-YTHDF2-mediated NLRP3 mRNA stabilization.
Yu T, Yang F, Yang J, Shu C, Zhang X, Liu Q, Liu Y, Liang X, Li M, Hu W, Ke B, et al.
Cell death and differentiation (2026) : . 202 003 Dot blot, MeRIP; tested species: human

Size-Dependent Layered Double Hydroxide Nanoparticles Promote Osteogenesis and Bone Regeneration via METTL3-Dependent N6-Methyladenosine Modification of Runx2 mRNA.
Zhu Y, Sun W, Huang Y, Li J, Jiang H, Luo C, Wan F, Zhou Z
International journal of nanomedicine (2026) 21: 611081. 202 003 Dot blot; tested species: mouse

FTO promotes bladder cancer progression and stemness-associated phenotypes.
Wu N, He X
Cytotechnology (2026) 783: 103. 202 003 Dot blot; tested species: human

m6A modification in the 3'‑leader region of EBOV genome antagonizes ISG20 to facilitate viral replication.
Zhao B, Cao Z, Zhang K, Xiao S, Shen X, Li F, Wu Y, Zhang B, Wang Q, Zhang H, Chuai X, et al.
International journal of biological macromolecules (2026) 339Pt 2: 149804. 202 003 Dot blot, MeRIP; tested species: human

N6-methyladenosine RNA modification regulates light intensity-dependent terpenoid biosynthesis in Schizonepeta tenuifolia.
Zhang M, Zhang Q, Chen Z, Wen S, Feng Y, Duan S, Wang HB, Jin HL
Plant biotechnology journal (2025) : . 202 003 Dot blot, MeRIP

Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation.
Quarto G, Li Greci A, Bizet M, Penning A, Primac I, Murisier F, Garcia-Martinez L, Borges RL, Gao Q, Cingaram PKR, Calonne E, et al.
Cell (2025) 1884: 998-1018.e26. 202 003 Dot blot, MeRIP; tested species: human,mouse

An m6A methyltransferase confers host resistance by degrading viral proteins through ubiquitination.
Guo J, Zhang T, Xie H, Hu H, Shi C, Zhao Y, Yin J, Xu G, Wu Z, Wang P, Liu J, et al.
Nature communications (2025) 161: 4821. 202 003 Dot blot, MeRIP

ALKBH5-mediated NPC2 mRNA m6A demethylation promotes resistance to oxaliplatin in colorectal cancer.
Wan P, Ren Y, Li HT
Functional & integrative genomics (2025) 251: 158. 202 003 Dot blot, MeRIP; tested species: human

IGF2BP1-mediated methylation of ABCA1 facilitates tumor progression by affecting cholesterol metabolism in lung adenocarcinoma.
Xu S, Liu K, Chen Z, Tang W, Chen Z
Amino acids (2025) 571: 42. 202 003 Dot blot; tested species: human

Heat stress responses mediated by N6-methyladenine DNA methylation in maize.
Guo W, Le L, Zhang D, Wei Z, Wang Y, Wu Y, Wuriyanghan H, Gu X, Pu L
Cell reports (2025) 448: 116058. 202 003 Dot blot, MeRIP

ALKBH5 modulates COL5A1 mRNA stability via m6A demethylation to promote tobacco carcinogen NNK-induced lung cancer occurrence and progression.
Du Y, Tu L, Zhou J, Huang H, Xu E, Chen D, Li X, Yang Q
Journal of advanced research (2025) : . 202 003 Dot blot; tested species: human

WTAP participates in the DNA damage response via an m6A-FOXM1-dependent manner in hepatocellular carcinoma.
Huang N, Bian Z, Xu C, Zhang Y, Liu L, Cui Z, Zhao S, Fan Q, Xue S, Chen Y, Pan Q, et al.
Cell death discovery (2025) 111: 397. 202 003 Dot blot; tested species: human

Symmetric adenine methylation is an essential DNA modification in the early-diverging fungus Rhizopus microsporus.
Lax C, Mondo SJ, Martínez JF, Muszewska A, Baumgart LA, Pérez-Ruiz JA, Carrillo-Marín P, LaButti K, Lipzen A, Zhang Y, Guo J, et al.
Nature communications (2025) 161: 3843. 202 003 Dot blot

Extracellular matrix stiffness reduces DNA 6 ma level to facilitate colorectal cancer progression via disrupting P53 binding to CDKN1A promoter.
Xie SA, Li X, Yin MY, Du F, Zhang ST, Zhu ST
Experimental hematology & oncology (2025) 141: 111. 202 003 Dot blot, IP, IHC, ELISA; tested species: human,mouse

BRD4 regulates m6A of ESPL1 mRNA via interaction with ALKBH5 to modulate breast cancer progression.
Zhang H, Lu L, Yi C, Jiang T, Lu Y, Yang X, Zhong K, Zhou J, Li J, Xie G, Chen Z, et al.
Acta pharmaceutica Sinica. B (2025) 153: 1552-1570. 202 003 Dot blot, MeRIP; tested species: human

IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression.
Tian Q, Dan G, Wang X, Zhu J, Chen C, Tang D, Wang Z, Chen D, Lei S, Yang C, Wang H, et al.
Cell death discovery (2025) 111: 22. 202 003 Dot blot, MeRIP; tested species: human

Characterization of the m6A Regulatory Gene Family in Phaseolus vulgaris L. and Functional Analysis of PvMTA in Response to BCMV Infection.
Wu W, Wang X, Liang X, Huang X, Nawaz MA, Jing C, Fan Y, Niu J, Wu J, Feng X
International journal of molecular sciences (2025) 266: . 202 003 Dot blot, MeRIP

Short-term and long-term high-fat diet promote metabolic disorder through reprogramming mRNA m6A in white adipose tissue by gut microbiota.
Liu Y, Liu J, Ren R, Xin Z, Luo Y, Chen Y, Huang C, Liu Y, Yang T, Wang X
Microbiome (2025) 131: 75. 202 003 Dot blot; tested species: mouse

CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia.
Qin X, Zhou K, Dong L, Yang L, Li W, Chen Z, Shen C, Han L, Li Y, Chan AKN, Pokharel SP, et al.
Theranostics (2025) 158: 3234-3256. 202 003 Dot blot; tested species: human

SARS-CoV-2 and HCoV-OC43 regulate host m6A modification via activation of the mTORC1 signalling pathway to facilitate viral replication.
Zhou S, Hui X, Wang W, Zhao C, Jin M, Qin Y, Chen M
Emerging microbes & infections (2025) 141: 2447620. 202 003 Dot blot, MeRIP; tested species: human

USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5.
Zhou X, Xia Q, Wang B, Li J, Liu B, Wang S, Huang M, Zhong R, Cheng SY, Wang X, Jiang X, et al.
Theranostics (2025) 156: 2293-2314. 202 003 Dot blot, MeRIP; tested species: human

Actl6a regulates autophagy via Sox2-dependent Atg5 and Atg7 expression to inhibit apoptosis in spinal cord injury.
Hao J, Yang Y, Xie L, Li Z, Ma B, Wang B, Chen J, Zeng Z, Zhou X
Journal of advanced research (2025) : . 202 003 Dot blot, MeRIP; tested species: mouse

Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer.
Zhang S, Zhang N, Wan T, He Y, Hao J, Liu Y, Liu Y, Chen B, Zhao W, Wang L, Luo D, et al.
Journal of experimental & clinical cancer research : CR (2025) 441: 41. 202 003 Dot blot, MeRIP; tested species: human

Reversible ALKBH5 cytosolic aggregation accelerates cellular senescence.
Chen L, Chen Z, Mo J, Xie Q, Lin W, Zheng H, Zou Y, Chen Y, Bian XW, Zhou Z, Jin G, et al.
Cell death and differentiation (2025) : . 202 003 Dot blot, ICC, MeRIP; tested species: human,mouse

m6A demethylase Fto inhibited macrophage activation and glycolysis in diabetic nephropathy via m6A/Npas2/Hif-1α axis.
Zhu S, Jiang L, Liu X, Chen C, Luo X, Jiang S, Yin J, Liu X, Wu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2025) 392: e70332. 202 003 Dot blot, MeRIP; tested species: human

Preventing postsurgical colorectal cancer relapse: A hemostatic hydrogel loaded with METTL3 inhibitor for CAR-NK cell therapy.
Tan Z, Tian L, Luo Y, Ai K, Zhang X, Yuan H, Zhou J, Ye G, Yang S, Zhong M, Li G, et al.
Bioactive materials (2025) 44: 236-255. 202 003 Dot blot; tested species: human

Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy.
Wang J, Ran Y, Li Z, Zhao T, Zhang F, Wang J, Liu Z, Chen X
Neural regeneration research (2025) 203: 887-899. 202 003 Dot blot; tested species: rat

The barley m6A demethylase HvALKBH1B undergoes phase separation to enhance immunity to a plant rhabdovirus.
Zang Y, Qiao JH, Liu DS, Gao DM, Zhang XW, Pan TT, Yang YZ, Wang XB, Gao Q
The Plant cell (2025) 379: . 202 003 Dot blot, MeRIP

Endurance exercise remodels skeletal muscle by suppressing Ythdf1-mediated myostatin expression.
Huang X, Xu C, Zhang J, Wu W, Wang Z, Pang Q, Liu Z, Liu B
Cell death & disease (2025) 161: 96. 202 003 Dot blot; tested species: mouse

Inhibition of GRK4 reduces arrhythmia susceptibility and alleviates connexin43 dysregulation after myocardial infarction.
Yu J, Zhao X, Hao Y, Tao Y, Gao Z, Li W, Wang J, Li X, Wang J, Yang Y, Liang Z, et al.
Biochemical pharmacology (2025) 239: 117035. 202 003 Dot blot, MeRIP; tested species: mouse

Epitranscriptomic reprogramming in response to low CO2 stress and m6A engineering to enhance biomass production in Nannochloropsis oceanica.
Zhu H, Wu Y, Feng M, Ouyang L, Su H, Wei L
The Plant journal : for cell and molecular biology (2025) 1243: e70566. 202 003 Dot blot, MeRIP

Acute exercise promotes WAT browning by remodeling mRNA m6A methylation.
Chen W, Liu Y, Liu J, Chen Y, Wang X
Life sciences (2025) 361: 123269. 202 003 Dot blot; tested species: mouse

Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity.
Wilkinson E, Cui YH, Yang Z, Verghese M, Yang S, Sun M, Zhu H, Peterson J, Wei J, Zhao Y, Chen M, et al.
Cell reports (2025) 4410: 116311. 202 003 Dot blot, MeRIP; tested species: human

Ovotoxicant VCD disrupts oocyte meiosis in mice by impairing m6A/IGF2BP3-mediated mRNA stability.
Li Y, Zhou Y, Liu J, Nie G, Cheng F, Yang H
Communications biology (2025) 91: 34. 202 003 Dot blot, MeRIP; tested species: mouse

Inhibition of Mettl3-mediated m6A RNA modification of HMGCS1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucoma.
Wang C, Feng L, Fang W, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W, Xia X
International journal of surgery (London, England) (2025) 11112: 9147-9165. 202 003 Dot blot, MeRIP; tested species: rat

Helicobacter pylori infection aggravates hepatic steatosis by lactylation-driven WTAP-mediated m6A modification.
Chen H, Wang Z, Wang Y, Li S, Su W, Shao Y, Zhang G, Liu Y, Ye Q, Zhou X
Gut microbes (2025) 171: 2599543. 202 003 Dot blot, MeRIP; tested species: human,mouse

Domain associated with zinc fingers-containing NF90-NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity.
Higuchi T, Morioka S, Morisawa K, Matsukawa K, Ashida S, Suzuki T, Sakamoto S
FEBS open bio (2025) : . 202 003 Dot blot; tested species: human

IGF2BP3 recognizes m6A to regulate histone-to-protamine replacement during mouse sperm development.
Wang D, Huang Z, Zhou Y, Chen P, Chang G, Ke L, Jing C, Yang H, Zhao J, Ren S, Zheng Y, et al.
The EMBO journal (2025) : . 202 003 Dot blot, MeRIP; tested species: mouse

USP25 deubiquitinates cytosolic METTL3 to impede glioma proliferation via an m6A-independent pathway.
Zhang B, Han W, Gao X, Li W, Yu J, Zhao W, He J, Qiu X, Lu Z, Zhou L, Hu Y, et al.
iScience (2025) 2812: 113918. 202 003 Dot blot; tested species: human

The N6-methyladenosine Modified EphA10 Promotes Prostate Cancer Progression by Activating the ERK/AKT Pathway.
Hu L, Tong J, Tian D, Liu Q
Biochemical genetics (2025) : . 202 003 Dot blot, MeRIP; tested species: human

Global mapping of RNA N6-methyladenosine (m6A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity.
Rønningen T, Zeng Y, Dahl MB, Wang J, Visnovska T, Tannæs TM, la Cour Poulsen L, Cayir A, Svensson SIA, Svanevik M, Hertel JK, et al.
Biomarker research (2025) 131: 146. 202 003 Dot blot; tested species: human

N6-methyladenosine within transmissible gastroenteritis virus genomic RNA inhibits its replication via efficient recognition by RNA sensor RIG-I.
Chen J, Lin S, Liu Q, Gao M, Wang Z, Tang J, Cui Y, Tan C, Liu G
Journal of virology (2025) : e0137325. 202 003 Dot blot, MeRIP; tested species: pig

Targeting N6-methyladenosine demethylase FTO overcomes osimertinib resistance by inducing G0/G1 phase arrest in an m6A-dependent manner in lung adenocarcinoma.
Chen J, Hu C, Wu J, Liang Z, Qian J, Chen C, Huang H, Zhu Y, Zhao Y, Li Y
Biochemical pharmacology (2025) 242Pt 1: 117198. 202 003 Dot blot; tested species: human

METTL14-mediated m6A methylation of pri-miR-5099 to facilitate cardiomyocyte pyroptosis in myocardial infarction.
Yu H, Li QS, Guo JN, Zhang Z, Lang XZ, Liu YN, Qin L, Su X, Zhang QW, Xue YD, Gong LL, et al.
Acta pharmacologica Sinica (2025) 466: 1639-1651. 202 003 Dot blot, MeRIP; tested species: mouse

Deacetylation of ACLY Mediates RNA M6A-Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer.
Wen J, Shen M, Zhao H, Liu L, Hua Q, Zhao X, Liu J, Feng H, Huang G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025) : e03323. 202 003 Dot blot, MeRIP; tested species: human

Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction.
Cui LG, Zhai MM, Yin JJ, Wang ZM, Wang SH, Zhou YJ, Li PP, Wang Y, Xia L, Wang P, Cha XX, et al.
European journal of pharmacology (2025) 989: 177247. 202 003 Dot blot; tested species: rat

ALKBH5 promotes cardiac fibroblasts pyroptosis after myocardial infarction through Notch1/NLRP3 pathway.
Cui LG, Wang SH, Komal S, Yin JJ, Zhai MM, Zhou YJ, Yu QW, Wang C, Wang P, Wang ZM, Zafar AM, et al.
Cellular signalling (2025) 127: 111574. 202 003 Dot blot, MeRIP; tested species: rat

m6A RNA methylation modulates autophagy by targeting Map1lc3b in bisphenol A induced Leydig cell dysfunction.
Chen Z, Chen Z, Mo J, Chen Y, Chen L, Deng C
Journal of hazardous materials (2025) 485: 136748. 202 003 Dot blot; tested species: mouse

Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes.
Zhang X, Huang DX, Xuan C, Li Y, Jiang Y, Wu X, Zhou W, Lei Y, Yang F, Ma H, Hou K, et al.
Life sciences (2025) 361: 123294. 202 003 Dot blot, MeRIP; tested species: mouse

Fto-dependent Vdac3 m6A Modification Regulates Neuronal Ferroptosis Induced by the Post-ICH Mass Effect and Transferrin.
Xu Z, Li H, Li X, Lu J, Cao C, Peng L, Li L, Zhang J, Chen G
Neuroscience bulletin (2025) 416: 970-986. 202 003 Dot blot, ICC; tested species: mouse

WD40-protein-mediated crosstalk among three epigenetic marks regulates chromatin states and yield in rice.
Yang L, Li D, Guo W, Song J, Liu C, Liu H, Li C, Gu X
Molecular plant (2025) 187: 1143-1157. 202 003 Dot blot, MeRIP

m6A-Mediated Regulation of CYP417B1 Contributes to Imidacloprid Resistance in Bemisia tabaci.
Yang J, Xue H, Huang M, Wei X, Zhang R, Guo Z, Xie W, Wang S, Wu Q, Zhang Y, Yang X, et al.
Journal of agricultural and food chemistry (2025) 7327: 16766-16777. 202 003 Dot blot, MeRIP

Discovery of a Potent and Cell-Active Inhibitor of DNA 6mA Demethylase ALKBH1.
Xiong L, Li F, Guo Y, Zhang J, Xu K, Xiong Z, Tong A, Li L, Yang S
Journal of the American Chemical Society (2024) 14610: 6992-7006. 202 003 Dot blot; tested species: human

Inhibition of METTL3 ameliorates doxorubicin-induced cardiotoxicity through suppression of TFRC-mediated ferroptosis.
Wu L, Du Y, Wang L, Zhang Y, Ren J
Redox biology (2024) 72: 103157. 202 003 Dot blot, MeRIP; tested species: mouse,rat

ALKBH5 regulates paclitaxel resistance in NSCLC via inhibiting CEMIP-mediated EMT.
Gao L, Qiao L, Li Y, Jia L, Cui W, Yang J, Wu C, Wang L
Toxicology and applied pharmacology (2024) 483: 116807. 202 003 Dot blot; tested species: human

Pulsatile Flow Increases METTL14-induced m6A modification and attenuates septic cardiomyopathy: an experimental study.
Zhu S, Wang K, Yu Z, Tang W, Zhang Y, Umar Shinge SA, Qiang Y, Liu H, Zeng J, Qiao K, Liu C, et al.
International journal of surgery (London, England) (2024) 1107: 4103-15. 202 003 Dot blot; tested species: rat

LncRNA CCRR maintains Ca2+ homeostasis against myocardial infarction through the FTO-SERCA2a pathway.
Yang H, Xuan L, Wang S, Luo H, Duan X, Guo J, Cui S, Xin J, Hao J, Li X, Chen J, et al.
Science China. Life sciences (2024) : . 202 003 Dot blot; tested species: human

FTO elicits tumor neovascularization in cancer-associated fibroblasts through eliminating m6A modifications of multiple pro-angiogenic factors.
Liao Q, Shi H, Yang J, Ge S, Jia R, Song X, Chai P, Jia R
Cancer letters (2024) 592: 216911. 202 003 Dot blot, MeRIP; tested species: human

LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase.
Zeng J, Xie C, Huang Z, Cho CH, Chan H, Li Q, Ashktorab H, Smoot DT, Wong SH, Yu J, Gong W, et al.
Nature communications (2024) 151: 669. 202 003 Dot blot, IP; tested species: human

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis.
Zhang C, Yu M, Hepperla AJ, Zhang Z, Raj R, Zhong H, Zhou J, Hu L, Fang J, Liu H, Liang Q, et al.
The Journal of clinical investigation (2024) 1348: . 202 003 Dot blot, MeRIP; tested species: human

m6A RNA methylation drives kidney fibrosis by upregulating β-catenin signaling.
Long Y, Song D, Xiao L, Xiang Y, Li D, Sun X, Hong X, Hou FF, Fu H, Liu Y
International journal of biological sciences (2024) 208: 3185-3200. 202 003 Dot blot, MeRIP; tested species: mouse

Replicative senescence and high glucose induce the accrual of self-derived cytosolic nucleic acids in human endothelial cells.
Ramini D, Giuliani A, Kwiatkowska KM, Guescini M, Storci G, Mensà E, Recchioni R, Xumerle L, Zago E, Sabbatinelli J, Santi S, et al.
Cell death discovery (2024) 101: 184. 202 003 Dot blot; tested species: human

Dynamic DNA N 6-adenine methylation (6mA) governs the encystment process, showcased in the unicellular eukaryote Pseudocohnilembus persalinus.
Liu Y, Niu J, Ye F, Solberg T, Lu B, Wang C, Nowacki M, Gao S
Genome research (2024) 342: 256-271. 202 003 Dot blot, ICC

Colchicine Blocks Abdominal Aortic Aneurysm Development by Maintaining Vascular Smooth Muscle Cell Homeostasis.
Chen M, Yang D, Zhou Y, Yang C, Lin W, Li J, Liu J, Ye J, Huang W, Ma W, Li W, et al.
International journal of biological sciences (2024) 206: 2092-2110. 202 003 Dot blot, IHC, MeRIP; tested species: mouse,human

D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation.
Pianka ST, Li T, Prins TJ, Eldred BSC, Kevan BM, Liang H, Zapanta Rinonos S, Kornblum HI, Nathanson DA, Pellegrini M, Liau LM, et al.
Cancer research communications (2024) 43: 876-894. 202 003 Dot blot, MeRIP; tested species: human

m6A RNA methylation regulates mitochondrial function.
Kahl M, Xu Z, Arumugam S, Edens B, Fischietti M, Zhu AC, Platanias LC, He C, Zhuang X, Ma YC
Human molecular genetics (2024) : . 202 003 Dot blot, IP; tested species: mouse

Non-random spatial organization of telomeres varies during the cell cycle and requires LAP2 and BAF.
Keller D, Stinus S, Umlauf D, Gourbeyre E, Biot E, Olivier N, Mahou P, Beaurepaire E, Andrey P, Crabbe L
iScience (2024) 274: 109343. 202 003 Dot blot; tested species: human

METTL16 inhibits papillary thyroid cancer tumorigenicity through m6A/YTHDC2/SCD1-regulated lipid metabolism.
Li Q, Wang Y, Meng X, Wang W, Duan F, Chen S, Zhang Y, Sheng Z, Gao Y, Zhou L
Cellular and molecular life sciences : CMLS (2024) 811: 81. 202 003 Dot blot, MeRIP; tested species: human

METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability.
Sun X, Meng X, Piao Y, Dong S, Dong Q
International journal of medical sciences (2024) 214: 664-673. 202 003 Dot blot, IP, ICC; tested species: human

HIF-1α/m6A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity.
Cong X, Li X, Xu K, Yin L, Liang G, Sun R, Pu Y, Zhang J
Environment international (2024) 184: 108493. 202 003 Dot blot; tested species: human

No significant change of N6 -methyladenosine modification landscape in mouse brain after morphine exposure.
Wu X, Wu C, Zhou T
Brain and behavior (2024) 141: e3350. 202 003 Dot blot; tested species: mouse

Exposure to bisphenol A affects transcriptome-wide N6-methyladenine methylation in ovarian granulosa cells.
Zhang Y, Yan C, Xie Q, Wu B, Zhang Y
Ecotoxicology and environmental safety (2024) 272: 116071. 202 003 Dot blot; tested species: human

Identification of potential novel N6-methyladenosine effector-related lncRNA biomarkers for serous ovarian carcinoma: a machine learning-based exploration in the framework of 3P medicine.
Ye L, Tong X, Pan K, Shi X, Xu B, Yao X, Zhuo L, Fang S, Tang S, Jiang Z, Xue X, et al.
Frontiers in pharmacology (2024) 15: 1351929. 202 003 Dot blot, MeRIP; tested species: human

The ARID1A-METTL3-m6A axis ensures effective RNase H1-mediated resolution of R-loops and genome stability.
Zhang J, Chen F, Tang M, Xu W, Tian Y, Liu Z, Shu Y, Yang H, Zhu Q, Lu X, Peng B, et al.
Cell reports (2024) 432: 113779. 202 003 Dot blot; tested species: human

Aluminum causes irreversible damage to the development of hippocampal neurons by regulating m6A RNA methylation.
Yang L, Qi G, Rao W, Cen Y, Chen L, Li W, Pang Y
Toxicology letters (2024) 399: 34-42. 202 003 Dot blot; tested species: mouse

N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H, et al.
The Journal of biological chemistry (2024) 3009: 107598. 202 003 Dot blot, MeRIP; tested species: human

Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales.
Lax C, Mondo SJ, Osorio-Concepción M, Muszewska A, Corrochano-Luque M, Gutiérrez G, Riley R, Lipzen A, Guo J, Hundley H, Amirebrahimi M, et al.
Nature communications (2024) 151: 6066. 202 003 Dot blot

METTL3-mediated m6A modification of SIRT1 mRNA affects the progression of diabetic cataracts through cellular autophagy and senescence.
Dong S, Zhang J, Fu Y, Tang G, Chen J, Sun D, Qi Y, Zhou N
Journal of translational medicine (2024) 221: 865. 202 003 Dot blot; tested species: human

METTL14-mediated m6A methylation regulates pathological retinal neovascularization by targeting autophagy.
Yu Y, Nie H, Qin X, Chen X, Li X, Yao J
Experimental cell research (2024) 4431: 114291. 202 003 Dot blot, MeRIP; tested species: mouse

FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification of EPRS.
Wang J, Li Y, Deng L, Zha Y, Zhang S
Molecular medicine (Cambridge, Mass.) (2024) 301: 213. 202 003 Dot blot; tested species: rat

Methyltransferase Like-3-Mediated N6-Methyladenosine Modification of Long Noncoding RNA Hepatocyte Nuclear Factor 1a Antisense RNA 1/Hepatocyte Nuclear Factor 4a Antisense RNA 1 Regulates Cytochrome P450 Enzyme Expression.
Yu Y, Wang J, Xiong Z, Du A, Wang X, Wang Y, Han S, Wang P, Zhang L
Drug metabolism and disposition: the biological fate of chemicals (2024) 5210: 1104-1114. 202 003 Dot blot; tested species: human

FTO activates PD-L1 promotes immunosuppression in breast cancer via the m6A/YTHDF3/PDK1 axis under hypoxic conditions.
Wang S, Zhang X, Chen Q, Wu H, Cao S, Zhao S, Li G, Wang J, Gong Y, Wang X, Pang D, et al.
Journal of advanced research (2024) : . 202 003 Dot blot, MeRIP; tested species: human

Host RNA N6-methyladenosine and incoming DNA N6-methyldeoxyadenosine modifications cooperatively elevate the condensation potential of DNA to activate immune surveillance.
Wang N, Liu Q, Wang B, Yang Z, Li S, Li R, Liang X, Fan J, Wang H, Sun Z, Dong L, et al.
Molecular therapy : the journal of the American Society of Gene Therapy (2024) : . 202 003 Dot blot; tested species: mouse

Decoding the interplay between m6A modification and stress granule stability by live-cell imaging.
Li Q, Liu J, Guo L, Zhang Y, Chen Y, Liu H, Cheng H, Deng L, Qiu J, Zhang K, Goh WSS, et al.
Science advances (2024) 1046: eadp5689. 202 003 Dot blot, ICC, MeRIP; tested species: human

Ythdf2 facilitates precursor miR-378/miR-378-5p maturation to support myogenic differentiation.
Deng K, Su Y, Liu Z, Hu S, Ren C, Wei W, Fan Y, Zhang Y, Wang F
Cellular and molecular life sciences : CMLS (2024) 811: 445. 202 003 Dot blot

The METTL3/TRAP1 axis as a key regulator of 5-fluorouracil chemosensitivity in colorectal cancer.
Kang Q, Hu X, Chen Z, Liang X, Xiang S, Wang Z
Molecular and cellular biochemistry (2024) : . 202 003 Dot blot, MeRIP; tested species: human

METTL3 prevents granulosa cells mitophagy by regulating YTHDF2-mediated BNIP3 mRNA degradation due to arsenic exposure.
Zhang T, Niu J, Ren T, Lin H, He M, Sheng Z, Tong Y, Jin B, Wu Y, Pan J, Xiao Z, et al.
Ecotoxicology and environmental safety (2024) 286: 117233. 202 003 Dot blot, MeRIP; tested species: human,mouse

C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes.
Nabeel-Shah S, Pu S, Burns JD, Braunschweig U, Ahmed N, Burke GL, Lee H, Radovani E, Zhong G, Tang H, Marcon E, et al.
Molecular cell (2024) 8419: 3810-3825.e10. 202 003 Dot blot, MeRIP; tested species: human

The novel roles of RNA m6A modification in regulating the development, infection, and oxidative DNA damage repair of Phytophthora sojae.
Zhang F, Zhang B, Cui T, Chen S, Zhang C, Wang Z, Liu X
PLoS pathogens (2024) 209: e1012553. 202 003 Dot blot, MeRIP

m6A RNA methyltransferase METTL16 induces Cr(VI) carcinogenesis and lung cancer development through glutamine biosynthesis and GLUL expression.
Xie YX, Wang L, Zhou ZH, Liu WJ, Wang W, Yang JH, He ML, Qiu JG, Jiang BH
Journal of hazardous materials (2024) 480: 136093. 202 003 Dot blot, MeRIP; tested species: human

Lymphatic-specific methyltransferase-like 3-mediated m6A modification drives vascular patterning through prostaglandin metabolism reprogramming.
Shi L, Lu S, Han X, Ye F, Li X, Zhang Z, Jiang Q, Yan B
MedComm (2024) 510: e728. 202 003 Dot blot; tested species: human

Recruitment of the m6A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48.
Nabeel-Shah S, Pu S, Burke GL, Ahmed N, Braunschweig U, Farhangmehr S, Lee H, Wu M, Ni Z, Tang H, Zhong G, et al.
Genome biology (2024) 251: 246. 202 003 Dot blot, MeRIP; tested species: human

Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity.
Li F, Xiong L, Zhang J, Guo Y, Xu K, Xiong Z, Wang Y, Ji S, Tong A, Li L, Yang S, et al.
Journal of medicinal chemistry (2024) 6717: 15456-15475. 202 003 Dot blot; tested species: human

Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N6-methyladenosine (m6A) mediated silencing of SLC7A11.
Huang H, Lin Y, Xin J, Sun N, Zhao Z, Wang H, Duan L, Zhou Y, Liu X, Fang J, Jing B, et al.
Ecotoxicology and environmental safety (2024) 283: 116816. 202 003 Dot blot; tested species: human

mTOR Signaling Promotes Rapid m6A mRNA Methylation to Regulate NK-Cell Activation and Effector Functions.
Meng M, Zhong Z, Song L, Zhang Z, Yin X, Xie X, Tian L, Wu W, Yang Y, Deng Y, Peng H, et al.
Cancer immunology research (2024) 128: 1039-1057. 202 003 Dot blot, MeRIP; tested species: human,mouse

piR-27222 mediates PM2.5-induced lung cancer by resisting cell PANoptosis through the WTAP/m6A axis.
Ma W, Xu L, Wang Y, Chen S, Li D, Huo X, Li R, Zhu X, Chen N, Jin Y, Luo J, et al.
Environment international (2024) 190: 108928. 202 003 Dot blot, MeRIP; tested species: human

Cadmium exposure induces multigenerational inheritance of germ cell apoptosis and fertility suppression in Caenorhabditis elegans.
Huang X, Ye Q, Dai W, Zheng J, Li Y, Wang C, Luo Z, Yang J, Zhuo W, Wan QL
Environment international (2024) 191: 108952. 202 003 Dot blot

YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment.
Yang Z, Wang X, Fu Y, Wu W, Hu Z, Lin Q, Peng W, Pan Y, Wang J, Chen J, Hu D, et al.
Molecular cancer (2024) 231: 186. 202 003 Dot blot; tested species: human

Characterization of the m6A gene family in switchgrass and functional analysis of PvALKBH10 during flowering.
Liu H, Lin M, Zhou D, Liu B, Li X, Wang H, Bi X
Plant physiology and biochemistry : PPB (2024) 212: 108781. 202 003 Dot blot

QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism.
Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, et al.
Cell (2023) 18615: 3208-3226.e27. 202 003 Dot blot; tested species: human

N6-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation.
Wang Y, Traugot CM, Bubenik JL, Li T, Sheng P, Hiers NM, Fernandez P, Li L, Bian J, Swanson MS, Xie M, et al.
Molecular cell (2023) 8321: 3818-3834.e7. 202 003 Dot blot; tested species: human

Kupffer cell pyroptosis mediated by METTL3 contributes to the progression of alcoholic steatohepatitis.
Pan XS, Li BW, Wang LL, Li N, Lin HM, Zhang J, Du N, Zhu YQ, Wu X, Hu CM, Wu WY, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2023) 376: e22965. 202 003 Dot blot, ICC; tested species: mouse

RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity.
Yu F, Zhu AC, Liu S, Gao B, Wang Y, Khudaverdyan N, Yu C, Wu Q, Jiang Y, Song J, Jin L, et al.
Molecular cell (2023) 8312: 2003-2019.e6. 202 003 Dot blot; tested species: human

A Neuroligin-1 mutation associated with Alzheimer's disease produces memory and age-dependent impairments in hippocampal plasticity.
Arias-Aragón F, Tristán-Clavijo E, Martínez-Gallego I, Robles-Lanuza E, Coatl-Cuaya H, Martín-Cuevas C, Sánchez-Hidalgo AC, Rodríguez-Moreno A, Martinez-Mir A, Scholl FG
iScience (2023) 266: 106868. 202 003 Dot blot

Evaluation of N 6-methyldeoxyadenosine antibody-based genomic profiling in eukaryotes.
Debo BM, Mallory BJ, Stergachis AB
Genome research (2023) 333: 427-434. 202 003 Dot blot

YTHDF2 in dentate gyrus is the m6A reader mediating m6A modification in hippocampus-dependent learning and memory.
Zhuang M, Geng X, Han P, Che P, Liang F, Liu C, Yang L, Yu J, Zhang Z, Dong W, Ji SJ, et al.
Molecular psychiatry (2023) 284: 1679-1691. 202 003 Dot blot, IHC, MeRIP

Using integrated analysis from multicentre studies to identify RNA methylation-related lncRNA risk stratification systems for glioma.
Huang F, Wang X, Zhong J, Chen H, Song D, Xu T, Tian K, Sun P, Sun N, Qin J, Song Y, et al.
Cancer cell international (2023) 231: 156. 202 003 Dot blot; tested species: human

Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.
Li L, Sun Y, Davis AE, Shah SH, Hamed LK, Wu MR, Lin CH, Ding JB, Wang S
Cell reports (2023) 426: 112596. 202 003 Dot blot, MeRIP; tested species: mouse

Downregulation of ALKBH5 rejuvenates aged human mesenchymal stem cells and enhances their therapeutic efficacy in myocardial infarction.
Gao X, Liang X, Liu B, Hong Y, He H, Shen Y, Chen J, Huang X, Hu B, Li W, Li X, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2023) 3712: e23294. 202 003 Dot blot, IP, ICC; tested species: human

m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation.
Nan Y, Liu S, Luo Q, Wu X, Zhao P, Chang W, Zhang R, Li Y, Liu Z
Cell reports (2023) 4210: 113273. 202 003 Dot blot, MeRIP; tested species: human

Genome-wide adenine N6-methylation map reveals epigenomic regulation of lipid accumulation in Nannochloropsis.
Gong Y, Wang Q, Wei L, Liang W, Wang L, Lv N, Du X, Zhang J, Shen C, Xin Y, Sun L, et al.
Plant communications (2023) : 100773. 202 003 Dot blot

N6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic-ischemic neonatal rats.
Deng J, Liao Y, Chen J, Chen A, Wu S, Huang Y, Qian H, Gao F, Wu G, Chen Y, Chen X, et al.
Cell death & disease (2023) 1412: 820. 202 003 Dot blot; tested species: rat

Deciphering m6A dynamics at a single-base level during planarian anterior-posterior axis specification.
Chen L, Zhen H, Chen Z, Huang M, Mak DW, Jin W, Zou Y, Chen M, Zheng M, Xie Q, Zhou Z, et al.
Computational and structural biotechnology journal (2023) 21: 4567-4579. 202 003 Dot blot, IHC; tested species: mouse

METTL3-Mediated RNA m6A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2.
Lin Y, Luo G, Liu Q, Yang R, Sol Reinach P, Yan D
Investigative ophthalmology & visual science (2023) 6413: 18. 202 003 Dot blot; tested species: mouse

ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression.
Ye G, Li J, Yu W, Xie Z, Zheng G, Liu W, Wang S, Cao Q, Lin J, Su Z, Li D, et al.
Experimental & molecular medicine (2023) : . 202 003 Dot blot, IP; tested species: human

Altered m6A modification is involved YAP-mediated apoptosis response in 4-vinylcyclohexene diepoxide induced ovotoxicity.
Li Y, Li M, Liu J, Nie G, Yang H
Ecotoxicology and environmental safety (2023) 262: 115192. 202 003 Dot blot, MeRIP; tested species: rat

Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner.
Wu Y, Li J, Li C, Lu S, Wei X, Li Y, Xia W, Qian C, Wang Z, Liu M, Gu Y, et al.
The Journal of biological chemistry (2023) 2996: 104783. 202 003 Dot blot; tested species: human

m6A methylation regulates hypoxia-induced pancreatic cancer glycolytic metabolism through ALKBH5-HDAC4-HIF1α positive feedback loop.
Liu X, Feng M, Hao X, Gao Z, Wu Z, Wang Y, Du L, Wang C
Oncogene (2023) : . 202 003 Dot blot; tested species: human

LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer.
Dai J, Qu T, Yin D, Cui Y, Zhang C, Zhang E, Guo R
Cell death & disease (2023) 145: 312. 202 003 Dot blot; tested species: human

METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability.
Pan Y, Liu Y, Cui D, Yu S, Zhou Y, Zhou X, Du W, Zheng L, Wan M
BMC oral health (2023) 231: 209. 202 003 IHC-P (FFPE), Dot blot, IP; tested species: mouse

Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.
Xu A, Liu M, Huang MF, Zhang Y, Hu R, Gingold JA, Liu Y, Zhu D, Chien CS, Wang WC, Liao Z, et al.
Nature communications (2023) 141: 1694. 202 003 Dot blot; tested species: human

Phenotypic and transcriptomic impact of expressing mammalian TET2 in the Drosophila melanogaster model.
Ismail JN, Mantash S, Hallal M, Jabado N, Khoueiry P, Shirinian M
Epigenetics (2023) 181: 2192375. 202 003 Dot blot; tested species: drosophila

METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Wang X, Wang J, Zhao X, Wu H, Li J, Cheng Y, Guo Q, Cao X, Liang T, Sun L, Zhang G, et al.
Journal of translational medicine (2023) 211: 407. 202 003 Dot blot; tested species: human

MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m6A-YTHDF1 Axis in Myoblast Differentiation.
Yang X, Ning Y, Abbas Raza SH, Mei C, Zan L
Frontiers in veterinary science (2022) 9: 900924. 202 003 Dot blot, IP

m6A modifications regulate intestinal immunity and rotavirus infection.
Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, Qian C, Zhang G, Li R, Wang D, Ren X, et al.
eLife (2022) 11: . 202 003 Dot blot; tested species: mouse

Gene amplification-driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A-YTHDF2-dependent in lung adenocarcinoma.
Zhang C, Sun Q, Zhang X, Qin N, Pu Z, Gu Y, Yan C, Zhu M, Dai J, Wang C, Li N, et al.
Cancer communications (London, England) (2022) : . 202 003 Dot blot, IP; tested species: human

N6-methyladenosine modification of the Aedes aegypti transcriptome and its alteration upon dengue virus infection in Aag2 cell line.
Dai Z, Etebari K, Asgari S
Communications biology (2022) 51: 607. 202 003 Dot blot, IP

Structural basis for MTA1c-mediated DNA N6-adenine methylation.
Chen J, Hu R, Chen Y, Lin X, Xiang W, Chen H, Yao C, Liu L
Nature communications (2022) 131: 3257. 202 003 Dot blot

Fusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis.
Chen S, Zhang L, Li M, Zhang Y, Sun M, Wang L, Lin J, Cui Y, Chen Q, Jin C, Li X, et al.
Nature communications (2022) 131: 1248. 202 003 Dot blot, IP; tested species: human

METTL3-m6 A methylase regulates the osteogenic potential of bone marrow mesenchymal stem cells in osteoporotic rats via the Wnt signalling pathway.
Wu T, Tang H, Yang J, Yao Z, Bai L, Xie Y, Li Q, Xiao J
Cell proliferation (2022) : e13234. 202 003 Dot blot; tested species: rat

Alkbh1-mediated DNA N6-methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging.
Cai GP, Liu YL, Luo LP, Xiao Y, Jiang TJ, Yuan J, Wang M
Cell proliferation (2022) : e13178. 202 003 Dot blot, IP; tested species: mouse

Methyltransferase-like 14 suppresses growth and metastasis of renal cell carcinoma by decreasing long noncoding RNA NEAT1.
Liu T, Wang H, Fu Z, Wang Z, Wang J, Gan X, Wang A, Wang L
Cancer science (2022) 1132: 446-458. 202 003 Dot blot, IP; tested species: human

m6 A demethylase ALKBH5 drives denervation-induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling.
Liu Y, Zhou T, Wang Q, Fu R, Zhang Z, Chen N, Li Z, Gao G, Peng S, Yang D
Journal of cachexia, sarcopenia and muscle (2022) : . 202 003 Dot blot, IP; tested species: mouse

The enhanced genomic 6 mA metabolism contributes to the proliferation and migration of TSCC cells.
Xi L, Yang Y, Xu Y, Zhang F, Li J, Liu X, Zhang Z, Du Q
International journal of oral science (2022) 141: 11. 202 003 Dot blot, IHC-P (FFPE), ICC; tested species: human

FIONA1-Mediated m6 A Modification Regulates the Floral Transition in Arabidopsis.
Xu T, Wu X, Wong CE, Fan S, Zhang Y, Zhang S, Liang Z, Yu H, Shen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2022) : e2103628. 202 003 Dot blot, IP

DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-induced Hepatic Steatosis.
Luo L, Liu Y, Nizigiyimana P, Ye M, Xiao Y, Guo Q, Su T, Luo X, Huang Y, Zhou H
Cellular and molecular gastroenterology and hepatology (2022) : . 202 003 Dot blot, IHC-P (FFPE), IP; tested species: mouse

METTL3-mediated N 6-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication.
Suo L, Liu C, Zhang QY, Yao MD, Ma Y, Yao J, Jiang Q, Yan B
Theranostics (2022) 121: 277-289. 202 003 Dot blot, IP; tested species: human

m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration.
Liu Y, Song R, Zhao L, Lu Z, Li Y, Zhan X, Lu F, Yang J, Niu Y, Cao X
Signal transduction and targeted therapy (2022) 71: 194. 202 003 Dot blot, IP; tested species: mouse

Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA.
Hao W, Dian M, Zhou Y, Zhong Q, Pang W, Li Z, Zhao Y, Ma J, Lin X, Luo R, Li Y, et al.
Nature communications (2022) 131: 5845. 202 003 Dot blot, IP, ICC; tested species: mouse

Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila.
Perlegos AE, Shields EJ, Shen H, Liu KF, Bonini NM
Nature communications (2022) 131: 5387. 202 003 Dot blot, IP; tested species: drosophila

METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets.
Hsu KW, Lai JC, Chang JS, Peng PH, Huang CH, Lee DY, Tsai YC, Chung CJ, Chang H, Chang CH, Chen JL, et al.
Genome biology (2022) 231: 249. 202 003 Dot blot, IP, IHC; tested species: human

RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice.
Cheng P, Bao S, Li C, Tong J, Shen L, Yu H
Developmental cell (2022) 572: 246-259.e4. 202 003 Dot blot, IP

Protocol for the generation of HIV-1 genomic RNA with altered levels of N 6-methyladenosine.
Phillips S, Baek A, Kim S, Chen S, Wu L
STAR protocols (2022) 33: 101616. 202 003 Dot blot; tested species: human

IGF2BP3 is an essential N6-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells.
Xu X, Cui J, Wang H, Ma L, Zhang X, Guo W, Xue X, Wang Y, Qiu S, Tian X, Miao Y, et al.
Materials today. Bio (2022) 17: 100503. 202 003 Dot blot, IP; tested species: mouse

Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA.
Zhang R, Zhang Y, Guo F, Huang G, Zhao Y, Chen B, Wang C, Cui C, Shi Y, Li S, Cui H, et al.
Cell death discovery (2022) 81: 432. 202 003 Dot blot, IP; tested species: mouse

N6-methyladenosine RNA modification regulates photosynthesis during photodamage in plants.
Zhang M, Zeng Y, Peng R, Dong J, Lan Y, Duan S, Chang Z, Ren J, Luo G, Liu B, Růžička K, et al.
Nature communications (2022) 131: 7441. 202 003 Dot blot, IP

HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma.
Quan L, Jia C, Guo Y, Chen Y, Wang X, Xu Q, Zhang Y
Journal of translational medicine (2022) 201: 537. 202 003 Dot blot, IP; tested species: human

Interactive regulation of DNA demethylase gene TET1 and m6A methyltransferase gene METTL3 in myoblast differentiation.
Yang X, Mei C, Raza SHA, Ma X, Wang J, Du J, Zan L
International journal of biological macromolecules (2022) : . 202 003 Dot blot, IP; tested species: cow

N6-methyladenosine RNA modification promotes viral genomic RNA stability and infection.
Zhang T, Shi C, Hu H, Zhang Z, Wang Z, Chen Z, Feng H, Liu P, Guo J, Lu Q, Zhong K, et al.
Nature communications (2022) 131: 6576. 202 003 Dot blot, IP

FTO-mediated autophagy promotes progression of clear cell renal cell carcinoma via regulating SIK2 mRNA stability.
Xu Y, Zhou J, Li L, Yang W, Zhang Z, Zhang K, Ma K, Xie H, Zhang Z, Cai L, Gong Y, et al.
International journal of biological sciences (2022) 1815: 5943-5962. 202 003 Dot blot, IP; tested species: human

LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis.
Yang J, Qian X, Qiu Q, Xu L, Pan M, Li J, Ren J, Lu B, Qiu T, Chen E, Ying K, et al.
Cell death & disease (2022) 1310: 877. 202 003 Dot blot, IP; tested species: human

LncNAP1L6 activates MMP pathway by stabilizing the m6A-modified NAP1L2 to promote malignant progression in prostate cancer.
Zheng Y, Qi F, Li L, Yu B, Cheng Y, Ge M, Qin C, Li X
Cancer gene therapy (2022) : . 202 003 Dot blot, IP; tested species: human

Attenuated Duck Hepatitis A Virus Infection Is Associated With High mRNA Maintenance in Duckling Liver via m6A Modification.
Wu L, Quan W, Zhang Y, Wang M, Ou X, Mao S, Sun D, Yang Q, Wu Y, Wei Y, Jia R, et al.
Frontiers in immunology (2022) 13: 839677. 202 003 Dot blot, IP

Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N6 -methyladenosine Modification.
Qin F, Cai B, Zhao J, Zhang L, Zheng Y, Liu B, Gao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2021) 815: e2100606. 202 003 Dot blot; tested species: human

The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging.
Jiang ZX, Wang YN, Li ZY, Dai ZH, He Y, Chu K, Gu JY, Ji YX, Sun NX, Yang F, Li W, et al.
Cell death & disease (2021) 128: 744. 202 003 Dot blot; tested species: human

Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools.
Kychygina A, Dall'Osto M, Allen JAM, Cadoret JC, Piras V, Pickett HA, Crabbe L
Scientific reports (2021) 111: 13195. 202 003 Dot blot; tested species: human

ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1.
Han Z, Wang X, Xu Z, Cao Y, Gong R, Yu Y, Yu Y, Guo X, Liu S, Yu M, Ma W, et al.
Theranostics (2021) 116: 3000-3016. 202 003 Dot blot, IP; tested species: human

Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.
Liu X, Wang H, Zhao X, Luo Q, Wang Q, Tan K, Wang Z, Jiang J, Cui J, Du E, Xia L, et al.
Nature communications (2021) 121: 3780. 202 003 Dot blot; tested species: mouse

N6-methyldeoxyadenine and histone methylation mediate transgenerational survival advantages induced by hormetic heat stress.
Wan QL, Meng X, Dai W, Luo Z, Wang C, Fu X, Yang J, Ye Q, Zhou Q
Science advances (2021) 71: . 202 003 Dot blot, IP

Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Tong J, Wang X, Liu Y, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, et al.
Science advances (2021) 718: . 202 003 Dot blot; tested species: mouse

N6-methyladenine demethylase ALKBH1 inhibits the differentiation of skeletal muscle.
Diao LT, Xie SJ, Yu PJ, Sun YJ, Yang F, Tan YY, Tao S, Hou YR, Zheng LL, Xiao ZD, Zhang Q, et al.
Experimental cell research (2021) 4002: 112492. 202 003 Dot blot; tested species: mouse

Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.
Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, et al.
Nature communications (2021) 121: 2183. 202 003 Dot blot, IHC-P (FFPE), IP; tested species: human

RNA m6A Modification Functions in Larval Development and Caste Differentiation in Honeybee (Apis mellifera).
Wang M, Xiao Y, Li Y, Wang X, Qi S, Wang Y, Zhao L, Wang K, Peng W, Luo GZ, Xue X, et al.
Cell reports (2021) 341: 108580. 202 003 Dot blot, IP

METTL3-dependent N6-methyladenosine RNA modification mediates the atherogenic inflammatory cascades in vascular endothelium.
Chien CS, Li JY, Chien Y, Wang ML, Yarmishyn AA, Tsai PH, Juan CC, Nguyen P, Cheng HM, Huo TI, Chiou SH, et al.
Proceedings of the National Academy of Sciences of the United States of America (2021) 1187: . 202 003 Dot blot, IP; tested species: human,mouse

ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment.
Han Z, Xu Z, Yu Y, Cao Y, Bao Z, Gao X, Ye D, Yan G, Gong R, Xu J, Zhang L, et al.
Molecular therapy. Nucleic acids (2021) 26: 22-33. 202 003 Dot blot; tested species: human

N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages.
Chen S, Kumar S, Espada CE, Tirumuru N, Cahill MP, Hu L, He C, Wu L
PLoS pathogens (2021) 173: e1009421. 202 003 Dot blot; tested species: human

The FTO m6A demethylase inhibits the invasion and migration of prostate cancer cells by regulating total m6A levels.
Zhu K, Li Y, Xu Y
Life sciences (2021) 271: 119180. 202 003 Dot blot; tested species: human

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.
Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT, Mo S, Barin E, Velleca A, et al.
Cancer cell (2021) 397: 958-972.e8. 202 003 Dot blot; tested species: human

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, et al.
Molecular cell (2021) 815: 922-939.e9. 202 003 Dot blot, IP; tested species: human

Characterization of Long Non-coding RNAs Modified by m6A RNA Methylation in Skeletal Myogenesis.
Xie SJ, Tao S, Diao LT, Li PL, Chen WC, Zhou ZG, Hu YX, Hou YR, Lei H, Xu WY, Chen WJ, et al.
Frontiers in cell and developmental biology (2021) 9: 762669. 202 003 Dot blot, IP; tested species: human,mouse

m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection.
Xia Z, Xu J, Lu E, He W, Deng S, Gong AY, Strass-Soukup J, Martins GA, Lu G, Chen XM
Frontiers in immunology (2021) 12: 705232. 202 003 Dot blot, IP; tested species: human,mouse

Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.
Xie SJ, Lei H, Yang B, Diao LT, Liao JY, He JH, Tao S, Hu YX, Hou YR, Sun YJ, Peng YW, et al.
Frontiers in cell and developmental biology (2021) 9: 744171. 202 003 Dot blot, IP; tested species: mouse

Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, et al.
Molecular cell (2021) 8116: 3368-3385.e9. 202 003 Dot blot, IP; tested species: human

N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity.
Fernandes SB, Grova N, Roth S, Duca RC, Godderis L, Guebels P, Mériaux SB, Lumley AI, Bouillaud-Kremarik P, Ernens I, Devaux Y, et al.
Frontiers in genetics (2021) 12: 657171. 202 003 Dot blot, IHC; tested species: rat

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.
Yu F, Wei J, Cui X, Yu C, Ni W, Bungert J, Wu L, He C, Qian Z
Nucleic acids research (2021) 4910: 5779-5797. 202 003 Dot blot, IP; tested species: mouse

Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice.
Liu S, Xiu J, Zhu C, Meng K, Li C, Han R, Du T, Li L, Xu L, Liu R, Zhu W, et al.
Nature communications (2021) 121: 6937. 202 003 Dot blot; tested species: mouse

MicroRNA-501-3p inhibits the proliferation of kidney cancer cells by targeting WTAP.
He L, Chen S, Ying Y, Xie H, Li J, Ma X, Wang W, Shen H, Wang X, Zheng X, Xie L, et al.
Cancer medicine (2021) 1020: 7222-7232. 202 003 Dot blot; tested species: human

Changes in N6-Methyladenosine Modification Modulate Diabetic Cardiomyopathy by Reducing Myocardial Fibrosis and Myocyte Hypertrophy.
Ju W, Liu K, Ouyang S, Liu Z, He F, Wu J
Frontiers in cell and developmental biology (2021) 9: 702579. 202 003 Dot blot, IP; tested species: mouse

m6A modification regulates lung fibroblast-to-myofibroblast transition through modulating KCNH6 mRNA translation.
Zhang JX, Huang PJ, Wang DP, Yang WY, Lu J, Zhu Y, Meng XX, Wu X, Lin QH, Lv H, Xie H, et al.
Molecular therapy : the journal of the American Society of Gene Therapy (2021) : . 202 003 Dot blot, IP; tested species: human

Elimination of Calm1 long 3' UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice.
Bae B, Gruner HN, Lynch M, Feng T, So K, Oliver D, Mastick GS, Yan W, Pieraut S, Miura P
RNA (New York, N.Y.) (2020) : . 202 003 Dot blot; tested species: human

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Shen C, Sheng Y, Zhu AC, Robinson S, Jiang X, Dong L, Chen H, Su R, Yin Z, Li W, Deng X, et al.
Cell stem cell (2020) : . 202 003 Dot blot; tested species: human,mouse

Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, Yin R, Shan Y, Wen J, Xie X, Feng M, et al.
Cell stem cell (2020) : . 202 003 Dot blot; tested species: human

YTHDF2 promotes spermagonial adhesion through modulating MMPs decay via m6A/mRNA pathway.
Huang T, Liu Z, Zheng Y, Feng T, Gao Q, Zeng W
Cell death & disease (2020) 111: 37. 202 003 Dot blot, IP; tested species: mouse

FTO Demethylates Cyclin D1 mRNA and Controls Cell-Cycle Progression.
Hirayama M, Wei FY, Chujo T, Oki S, Yakita M, Kobayashi D, Araki N, Takahashi N, Yoshida R, Nakayama H, Tomizawa K, et al.
Cell reports (2020) 311: 107464. 202 003 Dot blot, IP; tested species: mouse

N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
Hao Z, Wu T, Cui X, Zhu P, Tan C, Dou X, Hsu KW, Lin YT, Peng PH, Zhang LS, Gao Y, et al.
Molecular cell (2020) : . 202 003 Dot blot, IP, ICC; tested species: human

Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA.
Zhang M, Yang S, Nelakanti R, Zhao W, Liu G, Li Z, Liu X, Wu T, Xiao A, Li H
Cell research (2020) : . 202 003 Dot blot

N6-methyladenine in DNA antagonizes SATB1 in early development.
Li Z, Zhao S, Nelakanti RV, Lin K, Wu TP, Alderman MH, Guo C, Wang P, Zhang M, Min W, Jiang Z, et al.
Nature (2020) : . 202 003 Dot blot, IP, ICC; tested species: mouse

Validation strategies for antibodies targeting modified ribonucleotides.
Weichmann F, Hett R, Schepers A, Ito-Kureha T, Flatley A, Slama K, Hastert F, Angstmann N, Cardoso CM, König J, Huettelmaier S, et al.
RNA (New York, N.Y.) (2020) : . 202 003 Dot blot, IP, ICC; tested species: human

METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA.
Wu Z, Shi Y, Lu M, Song M, Yu Z, Wang J, Wang S, Ren J, Yang YG, Liu GH, Zhang W, et al.
Nucleic acids research (2020) 4819: 11083-11096. 202 003 Dot blot, IP; tested species: human

Methyl Adenine Identification (MadID): High-Resolution Detection of Protein-DNA Interactions.
Umlauf D, Sobecki M, Crabbe L
Methods in molecular biology (Clifton, N.J.) (2020) 2175: 123-138. 202 003 Dot blot, IP, ICC; tested species: human

Melatonin restores the pluripotency of long-term-cultured embryonic stem cells through melatonin receptor-dependent m6A RNA regulation.
Yang L, Liu X, Song L, Su G, Di A, Bai C, Wei Z, Li G
Journal of pineal research (2020) 692: e12669. 202 003 Dot blot, IP; tested species: mouse

N6-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury.
Xu K, Mo Y, Li D, Yu Q, Wang L, Lin F, Kong C, Balelang MF, Zhang A, Chen S, Dai Q, et al.
Therapeutic advances in chronic disease (2020) 11: 2040622320916024. 202 003 Dot blot, IHC-P (FFPE), ICC; tested species: rat

FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling.
Huang H, Wang Y, Kandpal M, Zhao G, Cardenas H, Ji Y, Chaparala A, Tanner EJ, Chen J, Davuluri RV, Matei D, et al.
Cancer research (2020) 8016: 3200-3214. 202 003 Dot blot, IP; tested species: human

The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function.
Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, Xu X, Niu Y, Guo S, Zhang C, Qiu S, et al.
Redox biology (2020) 38: 101801. 202 003 Dot blot; tested species: mouse

MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.
Qiu Z, Lin AP, Jiang S, Elkashef SM, Myers J, Srikantan S, Sasi B, Cao JZ, Godley LA, Rakheja D, Lyu Y, et al.
Cell chemical biology (2020) 275: 538-550.e7. 202 003 Dot blot; tested species: human

Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, et al.
Cell research (2020) : . 202 003 Dot blot, IP; tested species: human

METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes.
Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, Jin J, Ding X, Wu S, Huang H, Yu T, et al.
Autophagy (2019) : 1-19. 202 003 Dot blot, IP; tested species: human,rat

Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site.
Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, Kankuri E, Karelson M
Cell reports (2019) 2613: 3762-3771.e5. 202 003 Dot blot; tested species: human

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, Ni T, Zhang ZS, Zhang T, Li C, Han L, et al.
Cancer cell (2019) 354: 677-691.e10. 202 003 Dot blot, IP; tested species: human

Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation.
Wang H, Hu X, Huang M, Liu J, Gu Y, Ma L, Zhou Q, Cao X
Nature communications (2019) 101: 1898. 202 003 Dot blot, IP; tested species: mouse

Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization.
Beh LY, Debelouchina GT, Clay DM, Thompson RE, Lindblad KA, Hutton ER, Bracht JR, Sebra RP, Muir TW, Landweber LF
Cell (2019) : . 202 003 Dot blot, IP

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY, et al.
Nature communications (2019) 101: 2782. 202 003 Dot blot, IP; tested species: human

Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication.
Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C
Plant physiology (2019) : . 202 003 Dot blot, IP

Meclofenamic acid represses spermatogonial proliferation through modulating m6A RNA modification.
Huang T, Guo J, Lv Y, Zheng Y, Feng T, Gao Q, Zeng W
Journal of animal science and biotechnology (2019) 10: 63. 202 003 Dot blot; tested species: mouse

Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications.
Matsuzawa S, Wakata Y, Ebi F, Isobe M, Kurosawa N
PloS one (2019) 1410: e0223197. 202 003 Dot blot

Newly identified DNA methyltransferases of Ixodes ricinus ticks.
Kotsarenko K, Vechtova P, Hammerova Z, Langova N, Malinovska L, Wimmerova M, Sterba J, Grubhoffer L
Ticks and tick-borne diseases (2019) : 101348. 202 003 Dot blot

The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells.
Zou D, Dong L, Li C, Yin Z, Rao S, Zhou Q
Cancer cell international (2019) 19: 321. 202 003 Dot blot, IP; tested species: human

m6A Methylation of Precursor-miR-320/RUNX2 Controls Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells.
Yan G, Yuan Y, He M, Gong R, Lei H, Zhou H, Wang W, Du W, Ma T, Liu S, Xu Z, et al.
Molecular therapy. Nucleic acids (2019) 19: 421-436. 202 003 Dot blot; tested species: human,mouse

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.
Elman JS, Ni TK, Mengwasser KE, Jin D, Wronski A, Elledge SJ, Kuperwasser C
Cell reports (2019) 2813: 3435-3449.e5. 202 003 Dot blot, IP; tested species: human,mouse

Transient Focal Ischemia Significantly Alters the m6A Epitranscriptomic Tagging of RNAs in the Brain.
Chokkalla AK, Mehta SL, Kim T, Chelluboina B, Kim J, Vemuganti R
Stroke (2019) : STROKEAHA119026433. 202 003 Dot blot, IP; tested species: mouse

Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons.
Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, Lin L, Wang F, Bao H, Jiao B, Lim J, et al.
Molecular cell (2018) : . 202 003 Dot blot, IP; tested species: drosophila

Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon.
Ni TK, Elman JS, Jin DX, Gupta PB, Kuperwasser C
Scientific reports (2018) 81: 1415. 202 003 Dot blot

Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels.
Li J, Meng S, Xu M, Wang S, He L, Xu X, Wang X, Xie L
Oncotarget (2018) 93: 3752-3764. 202 003 Dot blot; tested species: human

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, et al.
Nature cell biology (2018) 203: 285-295. 202 003 Dot blot, IP

Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Merkurjev D, Hong WT, Iida K, Oomoto I, Goldie BJ, Yamaguti H, Ohara T, Kawaguchi SY, Hirano T, Martin KC, Pellegrini M, et al.
Nature neuroscience (2018) : . 202 003 Dot blot, IP; tested species: mouse

A potentially abundant junctional RNA motif stabilized by m6A and Mg2.
Liu B, Merriman DK, Choi SH, Schumacher MA, Plangger R, Kreutz C, Horner SM, Meyer KD, Al-Hashimi HM
Nature communications (2018) 91: 2761. 202 003 Dot blot

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.
Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler-Reya RJ, Zhang Z, Ogawa Y, Kellis M, Duester G, Zhao JC, et al.
Nature neuroscience (2018) 212: 195-206. 202 003 Dot blot, IP

A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors.
Yan F, Al-Kali A, Zhang Z, Liu J, Pang J, Zhao N, He C, Litzow MR, Liu S
Cell research (2018) : . 202 003 Dot blot, IP; tested species: human

N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response.
Zhou J, Wan J, Shu XE, Mao Y, Liu XM, Yuan X, Zhang X, Hess ME, Brüning JC, Qian SB
Molecular cell (2018) 694: 636-647.e7. 202 003 Dot blot, IP; tested species: mouse

MadID, a Versatile Approach to Map Protein-DNA Interactions, Highlights Telomere-Nuclear Envelope Contact Sites in Human Cells.
Sobecki M, Souaid C, Boulay J, Guerineau V, Noordermeer D, Crabbe L
Cell reports (2018) 2510: 2891-2903.e5. 202 003 Dot blot, IP, ICC; tested species: human

DNA N6-Adenine Methylation in Arabidopsis thaliana.
Liang Z, Shen L, Cui X, Bao S, Geng Y, Yu G, Liang F, Xie S, Lu T, Gu X, Yu H, et al.
Developmental cell (2018) 453: 406-416.e3. 202 003 Dot blot, IP

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, et al.
Cell (2018) 1721-2: 90-105.e23. 202 003 Dot blot, IP; tested species: human

m6A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression.
Zhang P, He Q, Lei Y, Li Y, Wen X, Hong M, Zhang J, Ren X, Wang Y, Yang X, He Q, et al.
Cell death & disease (2018) 912: 1169. 202 003 Dot blot, IP; tested species: human

Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer.
Wang X, Li Z, Kong B, Song C, Cong J, Hou J, Wang S
Oncotarget (2017) 858: 98918-98930. 202 003 Dot blot

Transcriptome-wide N 6 -methyladenosine methylome profiling of porcine muscle and adipose tissues reveals a potential mechanism for transcriptional regulation and differential methylation pattern.
Tao X, Chen J, Jiang Y, Wei Y, Chen Y, Xu H, Zhu L, Tang G, Li M, Jiang A, Shuai S, et al.
BMC genomics (2017) 181: 336. 202 003 Dot blot, IP

RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, et al.
Nature (2017) 5437646: 573-576. 202 003 Dot blot, ICC

Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs.
Martínez-Pérez M, Aparicio F, López-Gresa MP, Bellés JM, Sánchez-Navarro JA, Pallás V
Proceedings of the National Academy of Sciences of the United States of America (2017) 11440: 10755-10760. 202 003 Dot blot, IP

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.
Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, Sun G, Lu Z, Huang Y, Yang CG, Riggs AD, et al.
Cell reports (2017) 1811: 2622-2634. 202 003 Dot blot; tested species: human

N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena.
Wang Y, Chen X, Sheng Y, Liu Y, Gao S
Nucleic acids research (2017) 4520: 11594-11606. 202 003 Dot blot, ICC

Mouse Maternal High-Fat Intake Dynamically Programmed mRNA m⁶A Modifications in Adipose and Skeletal Muscle Tissues in Offspring.
Li X, Yang J, Zhu Y, Liu Y, Shi X, Yang G
International journal of molecular sciences (2016) 178: . 202 003 Dot blot

DNA N6-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs.
Zhou C, Liu Y, Li X, Zou J, Zou S
Bone research (2016) 4: 16033. 202 003 Dot blot

The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation.
Zhang M, Zhang Y, Ma J, Guo F, Cao Q, Zhang Y, Zhou B, Chai J, Zhao W, Zhao R
PloS one (2015) 107: e0133788. 202 003 Dot blot; tested species: mouse

m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, et al.
Cell stem cell (2015) 163: 289-301. 202 003 Dot blot, IP

Genome-wide detection of high abundance N6-methyladenosine sites by microarray.
Li Y, Wang Y, Zhang Z, Zamudio AV, Zhao JC
RNA (New York, N.Y.) (2015) 218: 1511-8. 202 003 Dot blot

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.
Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR
Nature methods (2015) 128: 767-72. 202 003 Dot blot, IP; tested species: human,mouse

DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 Dot blot, IP

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, et al.
Cell research (2014) 2412: 1403-19. 202 003 Dot blot, IP

Methylation by NSun2 represses the levels and function of microRNA 125b.
Yuan S, Tang H, Xing J, Fan X, Cai X, Li Q, Han P, Luo Y, Zhang Z, Jiang B, Dou Y, et al.
Molecular and cellular biology (2014) 3419: 3630-41. 202 003 Dot blot

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR
Cell (2012) 1497: 1635-46. 202 003 Dot blot, MeRIP

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C, et al.
Nature chemical biology (2011) 712: 885-7. 202 003 Dot blot

Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution.
Dierks D, Garcia-Campos MA, Uzonyi A, Safra M, Edelheit S, Rossi A, Sideri T, Varier RA, Brandis A, Stelzer Y, van Werven F, et al.
Nature methods (2021) : . 202 003 IP; tested species: mouse

Correlations of m6A methylation-related mRNAs with thyroid cancer.
Jiang Z, Luo S, Lin Y, Zhang H, Yi R
Scientific reports (2026) 161: 5688. 202 003 IP; tested species: human

The AHCY-adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis.
Liao K, Cao F, Wei C, Qian ZY, Hu HR, Pan WF, Feng ZQ, Lian SM, Xiao ZX, Sheng H, Mo HY, et al.
Cell research (2026) : . 202 003 IP; tested species: human

YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis.
Yang S, Cui YH, Li H, Wei J, Park G, Sun M, Verghese M, Wilkinson E, Nam T, Lungstrom LL, Cui X, et al.
Nature communications (2025) 161: 9946. 202 003 IP; tested species: mouse

N6-methyladenosine RNA modification regulates the transcription of SLC7A11 through KDM6B and GATA3 to modulate ferroptosis.
Zhang H, Yi C, Li J, Lu Y, Wang H, Tao L, Zhou J, Tan Y, Li J, Chen Z, Asadikaram G, et al.
Journal of biomedical science (2025) 321: 8. 202 003 IP; tested species: human

METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner.
Cao F, Chen G, Xu Y, Wang X, Tang X, Zhang W, Song X, Yang X, Zeng W, Xie J
Cell death & disease (2024) 151: 43. 202 003 IP; tested species: mouse

IGF2BP3-mediated enhanced stability of MYLK represses MSC adipogenesis and alleviates obesity and insulin resistance in HFD mice.
Huang X, He W, Fan S, Li H, Ye G
Cellular and molecular life sciences : CMLS (2024) 811: 17. 202 003 IP; tested species: human

Cell type-specific regulation of m6 A modified RNAs in the aging Drosophila brain.
Perlegos AE, Byrns CN, Bonini NM
Aging cell (2024) : e14076. 202 003 IP; tested species: drosophila

A novel AML1-ETO/FTO positive feedback loop promotes leukemogenesis and Ara-C resistance via stabilizing IGFBP2 in t(8;21) acute myeloid leukemia.
Zhou W, Li S, Wang H, Zhou J, Li S, Chen G, Guan W, Fu X, Nervi C, Yu L, Li Y, et al.
Experimental hematology & oncology (2024) 131: 9. 202 003 IP; tested species: human

The m6A demethylases FTO and ALKBH5 aggravate the malignant progression of nasopharyngeal carcinoma by coregulating ARHGAP35.
Yang Z, Zhang S, Xiong J, Xia T, Zhu R, Miao M, Li K, Chen W, Zhang L, You Y, You B, et al.
Cell death discovery (2024) 101: 43. 202 003 IP; tested species: human

Dynamics of N6-methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc.
Liu L, Sun H, Zhang Y, Liu C, Zhuang Y, Liu M, Ai X, Long D, Huang B, Li C, Zhou Y, et al.
JOR spine (2024) 71: e1316. 202 003 IP; tested species: rat

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells.
Guo W, Wang Z, Zhang Y, Li Y, Du Q, Zhang T, Hu J, Yao Y, Zhang J, Xu Y, Cui X, et al.
Science bulletin (2024) 691: 82-96. 202 003 IP; tested species: mouse

Significant differences in the degree of genomic DNA N6-methyladenine modifications in Acidithiobacillus ferrooxidans with two different culture substrates.
Lin R, Liu J, Shan S, Zhang Y, Yang Y
PloS one (2024) 192: e0298204. 202 003 IP

Transcriptome-wide m6A methylation profile reveals its potential role underlying drought response in wheat (Triticum aestivum L.).
Pan Y, Jia Y, Liu W, Zhao Q, Pan W, Jia Y, Lv S, Liu X, Nie X
Planta (2024) 2603: 65. 202 003 IP

Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
Tarullo M, Fernandez Rodriguez G, Iaiza A, Venezia S, Macone A, Incocciati A, Masciarelli S, Marchioni M, Giorgis M, Lolli ML, Fornaseri F, et al.
ACS pharmacology & translational science (2024) 712: 4096-4111. 202 003 IP; tested species: human

Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production.
Su PA, Chang CH, Yen SB, Wu HY, Tung WJ, Hu YP, Chen YI, Lin MH, Shih C, Chen PJ, Tsai K, et al.
Proceedings of the National Academy of Sciences of the United States of America (2024) 12124: e2400378121. 202 003 IP; tested species: human

Enhanced HSP70 binding to m6A-methylated RNAs facilitates cold stress adaptation in mango seedlings.
Huang Y, Chen M, Chen D, Chen H, Xie Z, Dai S
BMC plant biology (2024) 241: 1114. 202 003 IP, MeRIP

The RNA m6A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J
Cell death & disease (2024) 153: 192. 202 003 IP; tested species: human

YTHDF2 governs muscle size through a targeted modulation of proteostasis.
Gilbert CJ, Rabolli CP, Golubeva VA, Sattler KM, Wang M, Ketabforoush A, Arnold WD, Lepper C, Accornero F
Nature communications (2024) 151: 2176. 202 003 IP; tested species: mouse

ALKBH5 promotes hypopharyngeal squamous cell carcinoma apoptosis by targeting TLR2 in a YTHDF1/IGF2BP2-mediated manner.
Ye J, Wu Y, Chen Y, Ren Y, Jiang X, Dong Z, Zhang J, Jin M, Chen X, Wang Z, Xiao M, et al.
Cell death discovery (2023) 91: 308. 202 003 IP; tested species: human

Single-nucleus multiomic mapping of m6A methylomes and transcriptomes in native populations of cells with sn-m6A-CT.
Hamashima K, Wong KW, Sam TW, Teo JHJ, Taneja R, Le MTN, Li QJ, Hanna JH, Li H, Loh YH
Molecular cell (2023) : . 202 003 IP; tested species: mouse

The Drosophila Nab2 RNA binding protein inhibits m6A methylation and male-specific splicing of Sex lethal transcript in female neuronal tissue.
Jalloh B, Lancaster CL, Rounds JC, Brown BE, Leung SW, Banerjee A, Morton DJ, Bienkowski RS, Fasken MB, Kremsky IJ, Tegowski M, et al.
eLife (2023) 12: . 202 003 IP; tested species: drosophila

Comprehensive analysis of m6A methylomes in idiopathic pulmonary arterial hypertension.
Huang T, Zeng Y, Yang Y, Fan H, Deng Y, Chen W, Liu J, Yang F, Li W, Xiao Y
Epigenetics (2023) 181: 2242225. 202 003 IP; tested species: human

N6-Methyladenosine Directly Regulates CD40L Expression in CD4+ T Lymphocytes.
van Vroonhoven ECN, Picavet LW, Scholman RC, van den Dungen NAM, Mokry M, Evers A, Lebbink RJ, Calis JJA, Vastert SJ, van Loosdregt J
Biology (2023) 127: . 202 003 IP; tested species: human

METTL14 mediates m6a modification on osteogenic proliferation and differentiation of bone marrow mesenchymal stem cells by regulating the processing of pri-miR-873.
Dong X, Liao B, Zhao J, Li X, Yan K, Ren K, Zhang X, Bao X, Guo W
Molecular medicine reports (2023) 283: . 202 003 IP; tested species: human

Rna M6 a Methylation Regulates Glycolysis of Beige Fat and Contributes to Systemic Metabolic Homeostasis.
Li Y, Zhang Y, Zhang T, Ping X, Wang D, Chen Y, Yu J, Liu C, Liu Z, Zheng Y, Yang Y, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023) : e2300436. 202 003 IP; tested species: mouse

The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells.
Leoni C, Bataclan M, Ito-Kureha T, Heissmeyer V, Monticelli S
Nature communications (2023) 141: 3862. 202 003 IP; tested species: mouse

The m6A reader PRRC2A is essential for meiosis I completion during spermatogenesis.
Tan X, Zheng C, Zhuang Y, Jin P, Wang F
Nature communications (2023) 141: 1636. 202 003 IP; tested species: mouse

N6-methyladenosine modification changes during the recovery processes for Paulownia witches' broom disease under the methyl methanesulfonate treatment.
Xu P, Huang S, Zhai X, Fan Y, Li X, Yang H, Cao Y, Fan G
Plant direct (2023) 77: e508. 202 003 IP

7SK methylation by METTL3 promotes transcriptional activity.
Perez-Pepe M, Desotell AW, Li H, Li W, Han B, Lin Q, Klein DE, Liu Y, Goodarzi H, Alarcón CR
Science advances (2023) 919: eade7500. 202 003 IP; tested species: human

m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations.
Ensinck I, Sideri T, Modic M, Capitanchik C, Vivori C, Toolan-Kerr P, van Werven FJ
RNA (New York, N.Y.) (2023) 295: 705-712. 202 003 IP

N6-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.
Wang X, Ding Y, Li R, Zhang R, Ge X, Gao R, Wang M, Huang Y, Zhang F, Zhao B, Liao W, et al.
Nature communications (2023) 141: 1185. 202 003 IP; tested species: human

M6A transcriptome-wide map of circRNAs identified in the testis of normal and AZ-treated Xenopus laevis.
Zhang X, Sai L, Zhang W, Kan X, Jia Q, Bo C, Yin W, Shao H, Han M, Peng C
Genes and environment : the official journal of the Japanese Environmental Mutagen Society (2023) 451: 23. 202 003 IP; tested species: frog

High glucose induces tau hyperphosphorylation in hippocampal neurons via inhibition of ALKBH5-mediated Dgkh m6A demethylation: a potential mechanism for diabetic cognitive dysfunction.
Qu M, Zuo L, Zhang M, Cheng P, Guo Z, Yang J, Li C, Wu J
Cell death & disease (2023) 146: 385. 202 003 IP; tested species: human

Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response.
Zhu J, Liu S, Fang J, Cui Z, Wang B, Wang Y, Liu L, Wang Q, Cao X
Cell reports (2023) 4210: 113192. 202 003 IP; tested species: mouse

Immunotoxicity Evaluation of Trihalophenolic Disinfection By-Products in Mouse and Human Mononuclear Macrophage Systems: The Role of RNA Epitranscriptomic Modification in Mammalian Immunity.
Qin M, Huang L, Li M, Shao T, Zhang J, Jiang X, Shao C, Zhao C, Pan Y, Zhou Q, Wang Y, et al.
Environmental health perspectives (2023) 13112: 127023. 202 003 IP; tested species: mouse

Changes in m6A RNA methylation are associated with male sterility in wolfberry.
Zhao J, Zhang C, Li S, Yuan M, Mu W, Yang J, Ma Y, Guan C, Ma C
BMC plant biology (2023) 231: 456. 202 003 IP

m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.
Shan T, Liu F, Wen M, Chen Z, Li S, Wang Y, Cheng H, Zhou Y
Molecular cell (2023) 8324: 4494-4508.e6. 202 003 IP; tested species: human

Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits.
Luo G, Gong R, Ai Y, Zhu T, Ren Z
Biology (2023) 1211: . 202 003 IP; tested species: rabbit

Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A.
Gu X, Zhuang A, Yu J, Yang L, Ge S, Ruan J, Jia R, Fan X, Chai P
Nucleic acids research (2023) : . 202 003 IP; tested species: human

FTO-mediated m6A demethylation regulates GnRH expression in the hypothalamus via the PLCβ3/Ca2+/CAMK signalling pathway.
Zang S, Yin X, Li P
Communications biology (2023) 61: 1297. 202 003 IP, IHC; tested species: rat

Transcriptome-wide N6-methyladenosine methylation profile of atherosclerosis in mice.
Zheng X, Zhou B, Li Y, Zhong H, Huang Z, Gu M
BMC genomics (2023) 241: 774. 202 003 IP; tested species: mouse

dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain.
Perlegos AE, Quan X, Donnelly KM, Shen H, Shields EJ, Elashal H, Fange Liu K, Bonini NM
Scientific reports (2023) 131: 22999. 202 003 IP

NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
Feng J, Xu T, He M, Li J, Yao P, Ma C, Yang S, Xu Z, Yan K, Chen X, Wang H, et al.
PLoS pathogens (2023) 1912: e1011808. 202 003 IP; tested species: human

mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons.
Loedige I, Baranovskii A, Mendonsa S, Dantsuji S, Popitsch N, Breimann L, Zerna N, Cherepanov V, Milek M, Ameres S, Chekulaeva M, et al.
Molecular cell (2023) 8315: 2709-2725.e10. 202 003 IP; tested species: mouse

Targeting YTHDF2 inhibits tumorigenesis of diffuse large B-cell lymphoma through ACER2-mediated ceramide catabolism.
Chen X, Lu T, Ding M, Cai Y, Yu Z, Zhou X, Wang X
Journal of advanced research (2023) : . 202 003 IP; tested species: human

RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation.
Chen H, Zhao X, Yang W, Zhang Q, Hao R, Jiang S, Han H, Yu Z, Xing S, Feng C, Wang Q, et al.
Nature communications (2023) 141: 6912. 202 003 IP; tested species: mouse

m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production.
Yang P, Wang Y, Ge W, Jing Y, Hu H, Yin J, Xue M, Wang Y, Li X, Li X, Shi Y, et al.
Free radical biology & medicine (2023) : . 202 003 IP; tested species: rat

Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia.
Zhang Y, Guo X, Chen Z, Guo R
European journal of medical research (2023) 281: 466. 202 003 IP; tested species: human

CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes.
Zheng Y, Li X, Deng S, Zhao H, Ye Y, Zhang S, Huang X, Bai R, Zhuang L, Zhou Q, Li M, et al.
Nature communications (2023) 141: 6334. 202 003 IP; tested species: human

MiR-141-3p promotes malignant progression in prostate cancer through AlkB homolog 5-mediated m6A modification of protein arginine methyltransferase 6.
Li X, Liu B, Wang S, Li J, Ge X
The Chinese journal of physiology (2023) 661: 43-51. 202 003 IP; tested species: mouse

USP47 inhibits m6A-dependent c-Myc translation to maintain regulatory T cell metabolic and functional homeostasis.
Wang A, Huang H, Shi JH, Yu X, Ding R, Zhang Y, Han Q, Ni ZY, Li X, Zhao R, Zou Q, et al.
The Journal of clinical investigation (2023) : . 202 003 IP; tested species: human

The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma.
Jin S, Li M, Chang H, Wang R, Zhang Z, Zhang J, He Y, Ma H
Molecular cancer (2022) 211: 97. 202 003 IP; tested species: human

YTHDF2 promotes intrahepatic cholangiocarcinoma progression and desensitises cisplatin treatment by increasing CDKN1B mRNA degradation.
Huang CS, Zhu YQ, Xu QC, Chen S, Huang Y, Zhao G, Ni X, Liu B, Zhao W, Yin XY
Clinical and translational medicine (2022) 126: e848. 202 003 IP; tested species: human

The m6A methylation regulates gonadal sex differentiation in chicken embryo.
Li J, Zhang X, Wang X, Sun C, Zheng J, Li J, Yi G, Yang N
Journal of animal science and biotechnology (2022) 131: 52. 202 003 IP; tested species: chicken

METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis.
Xiong Q, Liu C, Zheng X, Zhou X, Lei K, Zhang X, Wang Q, Lin W, Tong R, Xu R, Yuan Q, et al.
International journal of oral science (2022) 141: 26. 202 003 IP; tested species: mouse

Bioactive peptide inhibits acute myeloid leukemia cell proliferation by downregulating ALKBH5-mediated m6A demethylation of EIF4EBP1 and MLST8 mRNA.
Zhang L, Su X
Cellular oncology (Dordrecht) (2022) : . 202 003 IP; tested species: human

The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers.
Zhang Y, Ma Z, Li C, Wang C, Jiang W, Chang J, Han S, Lu Z, Shao Z, Wang Y, Wang H, et al.
Nature communications (2022) 131: 3061. 202 003 IP; tested species: human

Methyltransferase-like 3 leads to lung injury by up-regulation of interleukin 24 through N6-methyladenosine-dependent mRNA stability and translation efficiency in mice exposed to fine particulate matter 2.5.
He X, Zhang L, Liu S, Wang J, Liu Y, Xiong A, Jiang M, Luo L, Ying X, Li G
Environmental pollution (Barking, Essex : 1987) (2022) 308: 119607. 202 003 IP; tested species: mouse

N6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis.
Ma X, Cao J, Zhou Z, Lu Y, Li Q, Jin Y, Chen G, Wang W, Ge W, Chen X, Hu Z, et al.
Nature communications (2022) 131: 4148. 202 003 IP; tested species: human

GSK3β Exacerbates Myocardial Ischemia/Reperfusion Injury by Inhibiting Myc.
Wen C, Lan M, Tan X, Wang X, Zheng Z, Lv M, Zhao X, Luo H, Liu Y, Wei P, Yue R, et al.
Oxidative medicine and cellular longevity (2022) 2022: 2588891. 202 003 IP; tested species: mouse

Effect of Humantenine on mRNA m6A Modification and Expression in Human Colon Cancer Cell Line HCT116.
Wu Y, Chen X, Bao W, Hong X, Li C, Lu J, Zhang D, Zhu A
Genes (2022) 135: . 202 003 IP; tested species: human

N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma.
Tatekawa S, Tamari K, Chijimatsu R, Konno M, Motooka D, Mitsufuji S, Akita H, Kobayashi S, Murakumo Y, Doki Y, Eguchi H, et al.
Scientific reports (2022) 121: 11074. 202 003 IP; tested species: human

LncRNA EPR-induced METTL7A1 modulates target gene translation.
Briata P, Caputo L, Zapparoli E, Marcaccini E, Passalacqua M, Brondolo L, Bordo D, Rossi A, Nicoletti C, Bucci G, Puri PL, et al.
Nucleic acids research (2022) 5013: 7608-7622. 202 003 IP; tested species: mouse

Transcriptome-wide analysis of glioma stem cell specific m6A modifications in long-non-coding RNAs.
Steponaitis G, Stakaitis R, Valiulyte I, Krusnauskas R, Dragunaite R, Urbanavičiūtė R, Tamasauskas A, Skiriute D
Scientific reports (2022) 121: 5431. 202 003 IP; tested species: human

Transcriptome-Wide N6-Methyladenosine Methylome Alteration in the Rat Spinal Cord After Acute Traumatic Spinal Cord Injury.
Yu J, Chen H, Ma H, Zhang Z, Zhu X, Wang P, Liu R, Jin X, Zhao Y
Frontiers in neuroscience (2022) 16: 848119. 202 003 IP; tested species: rat

RNA demethylase ALKBH5 inhibits TGF-β-induced EMT by regulating TGF-β/SMAD signaling in non-small cell lung cancer.
Sun Z, Su Z, Zhou Z, Wang S, Wang Z, Tong X, Li C, Wang Y, Chen X, Lei Z, Zhang HT, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2022) 365: e22283. 202 003 IP; tested species: human

The m6A(m)-independent role of FTO in regulating WNT signaling pathways.
Kim H, Jang S, Lee YS
Life science alliance (2022) 55: . 202 003 IP; tested species: human

Identification and Molecular Analysis of m6A-circRNAs from Cashmere Goat Reveal Their Integrated Regulatory Network and Putative Functions in Secondary Hair Follicle during Anagen Stage.
Hui T, Zhu Y, Shen J, Bai M, Fan Y, Feng S, Wang Z, Zhao J, Zhang Q, Liu X, Gong T, et al.
Animals : an open access journal from MDPI (2022) 126: . 202 003 IP

The essential roles of m6A RNA modification to stimulate ENO1-dependent glycolysis and tumorigenesis in lung adenocarcinoma.
Ma L, Xue X, Zhang X, Yu K, Xu X, Tian X, Miao Y, Meng F, Liu X, Guo S, Qiu S, et al.
Journal of experimental & clinical cancer research : CR (2022) 411: 36. 202 003 IP; tested species: human

The m6A RNA methyltransferase METTL3/METTL14 promotes leukemogenesis through the mdm2/p53 pathway in acute myeloid leukemia.
Sang L, Wu X, Yan T, Naren D, Liu X, Zheng X, Zhang N, Wang H, Li Y, Gong Y
Journal of Cancer (2022) 133: 1019-1030. 202 003 IP; tested species: human

New insights into the central sympathetic hyperactivity post-myocardial infarction: Roles of METTL3-mediated m6 A methylation.
Qi L, Hu H, Wang Y, Hu H, Wang K, Li P, Yin J, Shi Y, Wang Y, Zhao Y, Lyu H, et al.
Journal of cellular and molecular medicine (2022) : . 202 003 IP; tested species: rat

METTL3 promotes colorectal carcinoma progression by regulating the m6A-CRB3-Hippo axis.
Pan J, Liu F, Xiao X, Xu R, Dai L, Zhu M, Xu H, Xu Y, Zhao A, Zhou W, Dang Y, et al.
Journal of experimental & clinical cancer research : CR (2022) 411: 19. 202 003 IP; tested species: human

METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m6A modification.
Xu Y, Lv D, Yan C, Su H, Zhang X, Shi Y, Ying K
Cancer cell international (2022) 221: 11. 202 003 IHC-P (FFPE), IP; tested species: human

m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis.
Gao M, Qi Z, Feng W, Huang H, Xu Z, Dong Z, Xu M, Han J, Kloeber JA, Huang J, Lou Z, et al.
The Journal of biological chemistry (2022) : 101563. 202 003 IP; tested species: human

FIONA1 is an RNA N6-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering.
Wang C, Yang J, Song P, Zhang W, Lu Q, Yu Q, Jia G
Genome biology (2022) 231: 40. 202 003 IP

Global profiling reveals common and distinct N6-methyladenosine (m6A) regulation of innate immune responses during bacterial and viral infections.
Feng J, Zhang T, Sorel O, Meng W, Zhang X, Lai Z, Yuan W, Chen Y, Huang Y, Gao SJ
Cell death & disease (2022) 133: 234. 202 003 IP; tested species: mouse

N6-methyladenosine modification regulates imatinib resistance of gastrointestinal stromal tumor by enhancing the expression of multidrug transporter MRP1.
Xu K, Zhang Q, Chen M, Li B, Wang N, Li C, Gao Z, Zhang D, Yang L, Xu Z, Li X, et al.
Cancer letters (2022) 530: 85-99. 202 003 IP; tested species: human

AS3MT facilitates NLRP3 inflammasome activation by m6A modification during arsenic-induced hepatic insulin resistance.
Qiu T, Wu C, Yao X, Han Q, Wang N, Yuan W, Zhang J, Shi Y, Jiang L, Liu X, Yang G, et al.
Cell biology and toxicology (2022) : . 202 003 IP; tested species: mouse

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Endometrioid Ovarian Cancer.
Yang L, Chen X, Qian X, Zhang J, Wu M, Yu A
Frontiers in oncology (2022) 12: 844613. 202 003 IP; tested species: human

ALKBH5-mediated m6A modification of lncRNA KCNQ1OT1 triggers the development of LSCC via upregulation of HOXA9.
Li Y, Yan B, Wang X, Li Q, Kan X, Wang J, Sun Y, Wang P, Tian L, Liu M
Journal of cellular and molecular medicine (2022) 262: 385-398. 202 003 IP; tested species: human

Reducing N6AMT1-mediated 6mA DNA modification promotes breast tumor progression via transcriptional repressing cell cycle inhibitors.
Chen J, Zhuang Y, Wang P, Ning J, Liu W, Huang Y, Lin X, Peng L, Zhang D
Cell death & disease (2022) 133: 216. 202 003 IP; tested species: human

YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m6A-dependent manner.
Lin Y, Jin X, Nie Q, Chen M, Guo W, Chen L, Li Y, Chen X, Zhang W, Chen H, Jiang M, et al.
Annals of translational medicine (2022) 102: 83. 202 003 IP; tested species: human

N6-methyladenosine (m6A) methyltransferase METTL3 regulates sepsis-induced myocardial injury through IGF2BP1/HDAC4 dependent manner.
Shen H, Xie K, Li M, Yang Q, Wang X
Cell death discovery (2022) 81: 322. 202 003 IP; tested species: rat

METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m6A-YTHDF2-dependent manner.
Li J, Yao H, Huang J, Li C, Zhang Y, Xu R, Wang Z, Long Z, Tang J, Wang L
Cell death & disease (2022) 138: 723. 202 003 IP; tested species: rat

The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer.
Huang J, Zhou W, Hao C, He Q, Tu X
PLoS genetics (2022) 1810: e1010366. 202 003 IP; tested species: human

Endothelial CYP2J2 overexpression restores the BRB via METTL3-mediated ANXA1 upregulation.
Zhao B, Huang J, Lou X, Yao K, Ye M, Mou Q, Wen Z, Duan Q, Zhang H, Zhao Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2022) 3611: e22619. 202 003 IP; tested species: rat

Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression.
Timcheva K, Dufour S, Touat-Todeschini L, Burnard C, Carpentier MC, Chuffart F, Merret R, Helsmoortel M, Ferré S, Grézy A, Couté Y, et al.
Cell reports (2022) 4111: 111784. 202 003 IP; tested species: human

The alteration of N6-methyladenosine (m6A) modification at the transcriptome-wide level in response of heat stress in bovine mammary epithelial cells.
Qi Y, Zhang Y, Zhang J, Wang J, Li Q
BMC genomics (2022) 231: 829. 202 003 IP; tested species: cow

High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome.
Chen LQ, Zhang Z, Chen HX, Xi JF, Liu XH, Ma DZ, Zhong YH, Ng WH, Chen T, Mak DW, Chen Q, et al.
Cell discovery (2022) 81: 138. 202 003 IP; tested species: human

Coordinated transcriptional and post-transcriptional epigenetic regulation during skeletal muscle development and growth in pigs.
Zhang D, Wu S, Zhang X, Ren S, Tang Z, Gao F
Journal of animal science and biotechnology (2022) 131: 146. 202 003 IP; tested species: mouse,pig

Chronic allergic asthma alters m6A epitranscriptomic tagging of mRNAs and lncRNAs in the lung.
Ni X, Li X, Hu B, Wang L
Bioscience reports (2022) 4212: . 202 003 IP; tested species: mouse

Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes (2022) 141: . 202 003 IP; tested species: human

Long Noncoding RNA and mRNA m6A Modification Analyses of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment Exposed to Static Mechanical Strain.
Sun W, Liu J, Zhang X, Zhang X, Gao J, Chen X, Wang X, Qin W, Jin Z
Stem cells international (2022) 2022: 6243004. 202 003 IP; tested species: human

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.
Niu F, Han P, Zhang J, She Y, Yang L, Yu J, Zhuang M, Tang K, Shi Y, Yang B, Liu C, et al.
eLife (2022) 11: . 202 003 IP, IHC; tested species: mouse

METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4.
Li M, Ye J, Xia Y, Li M, Li G, Hu X, Su X, Wang D, Zhao X, Lu F, Li J, et al.
Leukemia (2022) 3611: 2586-2595. 202 003 IP; tested species: human

circRERE regulates the expression of GBX2 through miR-1299 and ZC3H13/N6-methyladenosine (m6A) to promote growth and invasion of hepatocellular carcinoma cells.
Lin YH, Zhang BY, Chen ZS
Journal of biosciences (2022) 47: . 202 003 IP; tested species: human

Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis.
Xu W, He C, Kaye EG, Li J, Mu M, Nelson GM, Dong L, Wang J, Wu F, Shi YG, Adelman K, et al.
Molecular cell (2022) 826: 1156-1168.e7. 202 003 IP; tested species: human,mouse

METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability.
Chen L, Zhang C, Ma W, Huang J, Zhao Y, Liu H
Nucleic acids research (2022) : . 202 003 IP; tested species: human

m6A Methylation Analysis Reveals Networks and Key Genes Underlying the Coarse and Fine Wool Traits in a Full-sib Merino Family.
Hua G, Yang X, Ma Y, Li T, Wang J, Deng X
Biology (2022) 1111: . 202 003 IP; tested species: sheep

m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation.
Boo SH, Ha H, Kim YK
Cell reports (2022) 4010: 111317. 202 003 IP; tested species: human

FTO Prevents Thyroid Cancer Progression by SLC7A11 m6A Methylation in a Ferroptosis-Dependent Manner.
Ji FH, Fu XH, Li GQ, He Q, Qiu XG
Frontiers in endocrinology (2022) 13: 857765. 202 003 IP; tested species: human

RNA m6A Modification Changes in Postmortem Nucleus Accumbens of Subjects with Alcohol Use Disorder: A Pilot Study.
Liu Y, Zhang H
Genes (2022) 136: . 202 003 IP; tested species: human

Transcriptome-Wide m6A Methylome and m6A-Modified Gene Analysis in Asthma.
Sun D, Cai X, Shen F, Fan L, Yang H, Zheng S, Zhou L, Chen K, Wang Z
Frontiers in cell and developmental biology (2022) 10: 799459. 202 003 IP; tested species: mouse

N6-Methyladenosine Methylome Profiling of Muscle and Adipose Tissues Reveals Methylase-mRNA Metabolic Regulatory Networks in Fat Deposition of Rex Rabbits.
Luo G, Wang S, Ai Y, Li J, Ren Z
Biology (2022) 117: . 202 003 IP; tested species: rabbit

Identification and characterization of N6-methyladenosine circular RNAs in the spinal cord of morphine-tolerant rats.
Xing M, Deng M, Shi Y, Dai J, Ding T, Song Z, Zou W
Frontiers in neuroscience (2022) 16: 967768. 202 003 IP; tested species: rat

M 6A RNA Methylation-Based Epitranscriptomic Modifications in Plasticity-Related Genes via miR-124-C/EBPα-FTO-Transcriptional Axis in the Hippocampus of Learned Helpless Rats.
Roy B, Ochi S, Dwivedi Y
The international journal of neuropsychopharmacology (2022) : . 202 003 IP; tested species: rat

METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Li Y, He X, Lu X, Gong Z, Li Q, Zhang L, Yang R, Wu C, Huang J, Ding J, He Y, et al.
Nature communications (2022) 131: 6350. 202 003 IP; tested species: human

METTL3 regulates m6A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma.
Zhang ZW, Teng X, Zhao F, Ma C, Zhang J, Xiao LF, Wang Y, Chang M, Tian Y, Li C, Zhang Z, et al.
Cell reports (2022) 414: 111530. 202 003 IP; tested species: human,mouse

METTL3 promotes colorectal cancer metastasis by promoting the maturation of pri-microRNA-196b.
Huang L, Liang D, Zhang Y, Chen X, Chen J, Wen C, Liu H, Yang X, Yang X, Lin S
Journal of cancer research and clinical oncology (2022) : . 202 003 IP; tested species: human

METTL14 is required for exercise-induced cardiac hypertrophy and protects against myocardial ischemia-reperfusion injury.
Wang L, Wang J, Yu P, Feng J, Xu GE, Zhao X, Wang T, Lehmann HI, Li G, Sluijter JPG, Xiao J, et al.
Nature communications (2022) 131: 6762. 202 003 IP; tested species: mouse

HNRNPC impedes m6A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma.
Huang XT, Li JH, Zhu XX, Huang CS, Gao ZX, Xu QC, Zhao W, Yin XY
Cancer letters (2021) 518: 196-206. 202 003 IP; tested species: human

Vitamin B12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.
Mosca P, Robert A, Alberto JM, Meyer M, Kundu U, Hergalant S, Umoret R, Coelho D, Guéant JL, Leheup B, Dreumont N, et al.
Molecular nutrition & food research (2021) 6517: e2100206. 202 003 IP; tested species: mouse

Cigarette smoking induces aberrant N6-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Jin M, Li G, Liu W, Wu X, Zhu J, Zhao D, Zeng Z, Xiong M, Song Y, He X, Zhang Q, et al.
Cancer letters (2021) 518: 214-229. 202 003 IP; tested species: human

Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits.
Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, et al.
Nature metabolism (2021) 37: 940-953. 202 003 IP; tested species: mouse

A deep learning approach to automate whole-genome prediction of diverse epigenomic modifications in plants.
Wang Y, Zhang P, Guo W, Liu H, Li X, Zhang Q, Du Z, Hu G, Han X, Pu L, Tian J, et al.
The New phytologist (2021) 2322: 880-897. 202 003 IP

OsEDM2L mediates m6 A of EAT1 transcript for proper alternative splicing and polyadenylation regulating rice tapetal degradation.
Ma K, Han J, Zhang Z, Li H, Zhao Y, Zhu Q, Xie Y, Liu YG, Chen L
Journal of integrative plant biology (2021) 6311: 1982-1994. 202 003 IP

Integrated analysis of mRNA-m6A-protein profiles reveals novel insights into the mechanisms for cadmium-induced urothelial transformation.
Wu B, Jiang X, Huang Y, Ying X, Zhang H, Liu B, Li Z, Qi D, Ji W, Cai X
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2021) 266: 499-507. 202 003 IP; tested species: human

Analysis and verification of N6-methyladenosine-modified genes as novel biomarkers for clear cell renal cell carcinoma.
Yang Z, Peng B, Pan Y, Gu Y
Bioengineered (2021) : . 202 003 IP; tested species: human

Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells.
Li C, Shangguan Y, Zhu P, Dai W, Tang D, Ou M, Dai Y
Hereditas (2021) 1581: 40. 202 003 IP; tested species: human

The m6 A reader MhYTP2 regulates MdMLO19 mRNA stability and antioxidant genes translation efficiency conferring powdery mildew resistance in apple.
Guo T, Liu C, Meng F, Hu L, Fu X, Yang Z, Wang N, Jiang Q, Zhang X, Ma F
Plant biotechnology journal (2021) : . 202 003 IP

ADSCs enhance VEGFR3-mediated lymphangiogenesis via METTL3-mediated VEGF-C m6A modification to improve wound healing of diabetic foot ulcers.
Zhou J, Wei T, He Z
Molecular medicine (Cambridge, Mass.) (2021) 271: 146. 202 003 IP; tested species: mouse

N1-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.
Wang Y, Wang J, Li X, Xiong X, Wang J, Zhou Z, Zhu X, Gu Y, Dominissini D, He L, Tian Y, et al.
Nature communications (2021) 121: 6314. 202 003 IP; tested species: human

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis.
Kim H, Lee YS, Kim SM, Jang S, Choi H, Lee JW, Kim TD, Kim VN
Developmental cell (2021) 568: 1118-1130.e6. 202 003 IP; tested species: mouse

METTL3 regulates skeletal muscle specific miRNAs at both transcriptional and post-transcriptional levels.
Diao LT, Xie SJ, Lei H, Qiu XS, Huang MC, Tao S, Hou YR, Hu YX, Sun YJ, Zhang Q, Xiao ZD, et al.
Biochemical and biophysical research communications (2021) 552: 52-58. 202 003 IP; tested species: mouse

m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype.
Liu P, Li F, Lin J, Fukumoto T, Nacarelli T, Hao X, Kossenkov AV, Simon MC, Zhang R
Nature cell biology (2021) 234: 355-365. 202 003 IP; tested species: human

m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity.
Qin Y, Li B, Arumugam S, Lu Q, Mankash SM, Li J, Sun B, Li J, Flavell RA, Li HB, Ouyang X, et al.
Cell reports (2021) 376: 109968. 202 003 IP; tested species: human

Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in infant rhesus macaques after multiple sevoflurane anesthesia.
Chen X, Shi L, Zhang L, Cheng Y, Xue Z, Yan J, Jiang H
Neuroscience (2021) : . 202 003 IP; tested species: monkey

N6 -methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression.
Deng J, Zhang J, Ye Y, Liu K, Zeng L, Huang J, Pan L, Li M, Bai R, Zhuang L, Huang X, et al.
Cancer research (2021) 8120: 5268-5283. 202 003 IP; tested species: human,mouse

Dynamic regulation of N6,2'-O-dimethyladenosine (m6Am) in obesity.
Ben-Haim MS, Pinto Y, Moshitch-Moshkovitz S, Hershkovitz V, Kol N, Diamant-Levi T, Beeri MS, Amariglio N, Cohen HY, Rechavi G
Nature communications (2021) 121: 7185. 202 003 IP; tested species: mouse

Profiling of N6-Methyladenosine (m6A) Modification Landscape in Response to Drought Stress in Apple (Malus prunifolia (Willd.) Borkh).
Mao X, Hou N, Liu Z, He J
Plants (Basel, Switzerland) (2021) 111: . 202 003 IP

N6 -methyladenosine modification of circular RNA circ-ARL3 facilitates Hepatitis B virus-associated hepatocellular carcinoma via sponging miR-1305.
Rao X, Lai L, Li X, Wang L, Li A, Yang Q
IUBMB life (2021) 732: 408-417. 202 003 IP; tested species: human

METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome.
Shi W, Yang F, Dai R, Sun Y, Chu Y, Liao S, Hao B
Frontiers in cell and developmental biology (2021) 9: 621374. 202 003 IP; tested species: human

m6A mRNA Methylation Regulates LKB1 to Promote Autophagy of Hepatoblastoma Cells through Upregulated Phosphorylation of AMPK.
Li G, Deng L, Huang N, Cui Z, Wu Q, Ma J, Pan Q, Sun F
Genes (2021) 1211: . 202 003 IP; tested species: human

Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
McFadden MJ, McIntyre ABR, Mourelatos H, Abell NS, Gokhale NS, Ipas H, Xhemalçe B, Mason CE, Horner SM
Cell reports (2021) 349: 108798. 202 003 IP; tested species: human

Transcriptome-wide m6A methylation profile reveals regulatory networks in roots of barley under cadmium stress.
Su T, Fu L, Kuang L, Chen D, Zhang G, Shen Q, Wu D
Journal of hazardous materials (2021) 423Pt A: 127140. 202 003 IP

Regulation of AR mRNA translation in response to acute AR pathway inhibition.
Somasekharan SP, Saxena N, Zhang F, Beraldi E, Huang JN, Gentle C, Fazli L, Thi M, Sorensen PH, Gleave M
Nucleic acids research (2021) : . 202 003 IP; tested species: human

Specific Regulation of m6A by SRSF7 Promotes the Progression of Glioblastoma.
Cun Y, An S, Zheng H, Lan J, Chen W, Luo W, Yao C, Li X, Huang X, Sun X, Wu Z, et al.
Genomics, proteomics & bioinformatics (2021) : . 202 003 IP; tested species: human

ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling.
He Y, Yue H, Cheng Y, Ding Z, Xu Z, Lv C, Wang Z, Wang J, Yin C, Hao H, Chen C, et al.
Cell death & disease (2021) 1212: 1121. 202 003 IP; tested species: human

Alteration of the m6A methylation landscape in a mouse model of scleroderma.
Shen L, Yu Y, Jiang M, Zhao J
Epigenomics (2021) : . 202 003 IP; tested species: mouse

Genome-wide identification and characterization of circular RNA m6A modification in pancreatic cancer.
Ye Y, Feng W, Zhang J, Zhu K, Huang X, Pan L, Su J, Zheng Y, Li R, Deng S, Bai R, et al.
Genome medicine (2021) 131: 183. 202 003 IP; tested species: human

RNA m6 A methylation regulates virus-host interaction and EBNA2 expression during Epstein-Barr virus infection.
Zheng X, Wang J, Zhang X, Fu Y, Peng Q, Lu J, Wei L, Li Z, Liu C, Wu Y, Yan Q, et al.
Immunity, inflammation and disease (2021) 92: 351-362. 202 003 IP; tested species: human

N6-methyladenosine regulates ATM expression and downstream signaling.
Zhang X, Liu P, Zheng X, Wang J, Peng Q, Li Z, Wei L, Liu C, Wu Y, Wen Y, Yan Q, et al.
Journal of Cancer (2021) 1223: 7041-7051. 202 003 IP; tested species: human

Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease.
Ruan H, Yang F, Deng L, Yang D, Zhang X, Li X, Pang L
Scientific reports (2021) 111: 20478. 202 003 IP; tested species: human

Quantitative profiling of N6-methyladenosine at single-base resolution in stem-differentiating xylem of Populus trichocarpa using Nanopore direct RNA sequencing.
Gao Y, Liu X, Wu B, Wang H, Xi F, Kohnen MV, Reddy ASN, Gu L
Genome biology (2021) 221: 22. 202 003 IP

The N6-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6.
Li Z, Wang P, Li J, Xie Z, Cen S, Li M, Liu W, Ye G, Zheng G, Ma M, Wang S, et al.
Cell death & disease (2021) 126: 578. 202 003 IP; tested species: mouse

WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis.
Yang X, Shao F, Guo D, Wang W, Wang J, Zhu R, Gao Y, He J, Lu Z
Cell death & disease (2021) 125: 462. 202 003 IP; tested species: human

The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Zong X, Xiao X, Shen B, Jiang Q, Wang H, Lu Z, Wang F, Jin M, Min J, Wang F, Wang Y, et al.
Nucleic acids research (2021) : . 202 003 IP; tested species: human

Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Yang R, Lee EE, Kim J, Choi JH, Kolitz E, Chen Y, Crewe C, Salisbury NJH, Scherer PE, Cockerell C, Smith TR, et al.
PLoS pathogens (2021) 175: e1009582. 202 003 IP; tested species: human

Sec62 promotes stemness and chemoresistance of human colorectal cancer through activating Wnt/β-catenin pathway.
Liu X, Su K, Sun X, Jiang Y, Wang L, Hu C, Zhang C, Lu M, Du X, Xing B
Journal of experimental & clinical cancer research : CR (2021) 401: 132. 202 003 IP; tested species: human

Transcriptome-wide study revealed m6A regulation of embryonic muscle development in Dingan goose (Anser cygnoides orientalis).
Xu T, Xu Z, Lu L, Zeng T, Gu L, Huang Y, Zhang S, Yang P, Wen Y, Lin D, Xing M, et al.
BMC genomics (2021) 221: 270. 202 003 IP; tested species: muscle

Mettl14-mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis.
Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, Shao M, Zhou Y, Chen M, Gong Y, Li C, et al.
Cellular and molecular gastroenterology and hepatology (2021) : . 202 003 IP; tested species: mouse

Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing.
Mendel M, Delaney K, Pandey RR, Chen KM, Wenda JM, Vågbø CB, Steiner FA, Homolka D, Pillai RS
Cell (2021) 18412: 3125-3142.e25. 202 003 IP; tested species: human,mouse

R-loop resolution promotes co-transcriptional chromatin silencing.
Xu C, Wu Z, Duan HC, Fang X, Jia G, Dean C
Nature communications (2021) 121: 1790. 202 003 IP

Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
Dai DL, Li X, Wang L, Xie C, Jin Y, Zeng MS, Zuo Z, Xia TL
The Journal of biological chemistry (2021) : 100547. 202 003 IP; tested species: human

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression.
Regué L, Zhao L, Ji F, Wang H, Avruch J, Dai N
Molecular metabolism (2021) : 101209. 202 003 IP; tested species: mouse

Comprehensive analysis of the transcriptome-wide m6A methylome in invasive malignant pleomorphic adenoma.
Han Z, Yang B, Wang Q, Hu Y, Wu Y, Tian Z
Cancer cell international (2021) 211: 142. 202 003 IP; tested species: human

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.
Xu F, Li J, Ni M, Cheng J, Zhao H, Wang S, Zhou X, Wu X
Molecular cancer (2021) 201: 45. 202 003 IP; tested species: mouse

Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels HH, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, et al.
The EMBO journal (2021) : e104975. 202 003 IP

RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.
Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, et al.
Cell research (2021) : . 202 003 IP; tested species: human

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding.
Wang W, Shao F, Yang X, Wang J, Zhu R, Yang Y, Zhao G, Guo D, Sun Y, Wang J, Xue Q, et al.
Nature communications (2021) 121: 3803. 202 003 IP; tested species: human

Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1.
Zhou P, Qi Y, Fang X, Yang M, Zheng S, Liao C, Qin F, Liu L, Li H, Li Y, Ravindran E, et al.
iScience (2021) 246: 102645. 202 003 IP; tested species: mouse

FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.
Ruan DY, Li T, Wang YN, Meng Q, Li Y, Yu K, Wang M, Lin JF, Luo LZ, Wang DS, Lin JZ, et al.
Oncogene (2021) : . 202 003 IP; tested species: human

m6A mRNA methylation regulates the development of gestational diabetes mellitus in Han Chinese women.
Wang J, Wang K, Liu W, Cai Y, Jin H
Genomics (2021) 1133: 1048-1056. 202 003 IP; tested species: human

Transcriptome-wide m6A profiling reveals mRNA post-transcriptional modification of boar sperm during cryopreservation.
Qin Z, Wang W, Ali MA, Wang Y, Zhang Y, Zhang M, Zhou G, Yang JD, Zeng C
BMC genomics (2021) 221: 588. 202 003 IP; tested species: pig

Decreased m6A Modification of CD34/CD276(B7-H3) Leads to Immune Escape in Colon Cancer.
Zhou Y, Zhou H, Shi J, Guan A, Zhu Y, Hou Z, Li R
Frontiers in cell and developmental biology (2021) 9: 715674. 202 003 IP; tested species: human

Transcriptome-wide m6A methylome during osteogenic differentiation of human adipose-derived stem cells.
Sun W, Song Y, Xia K, Yu L, Huang X, Zhao Z, Liu J
Stem cell research & therapy (2021) 121: 489. 202 003 IP; tested species: human

METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1.
Lu Z, Liu H, Song N, Liang Y, Zhu J, Chen J, Ning Y, Hu J, Fang Y, Teng J, Zou J, et al.
Cell death & disease (2021) 1210: 881. 202 003 IP; tested species: mouse

Alpha-ketoglutarate-dependent dioxygenase homolog 10B, an N6 -methyladenosine mRNA demethylase, plays a role in salt stress and abscisic acid responses in Arabidopsis thaliana.
Shoaib Y, Hu J, Manduzio S, Kang H
Physiologia plantarum (2021) : . 202 003 IP

Comprehensive profiling analysis of the N6-methyladenosine-modified circular RNA transcriptome in cultured cells infected with Marek's disease virus.
Sun A, Wang R, Yang S, Zhu X, Liu Y, Teng M, Zheng L, Luo J, Zhang G, Zhuang G
Scientific reports (2021) 111: 11084. 202 003 IP; tested species: chicken

YTHDF2 inhibit the tumorigenicity of endometrial cancer via downregulating the expression of IRS1 methylated with m6A.
Hong L, Pu X, Gan H, Weng L, Zheng Q
Journal of Cancer (2021) 1213: 3809-3818. 202 003 IP; tested species: human

m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity.
Zhou J, Zhang X, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, et al.
Science advances (2021) 725: . 202 003 IP; tested species: mouse

Hepatitis B virus X protein recruits methyltransferases to affect cotranscriptional N6-methyladenosine modification of viral/host RNAs.
Kim GW, Siddiqui A
Proceedings of the National Academy of Sciences of the United States of America (2021) 1183: . 202 003 IP; tested species: human

m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2.
Qian B, Wang P, Zhang D, Wu L
Cell death discovery (2021) 71: 157. 202 003 IP, ICC; tested species: mouse

N6-methyladenosine modification of HCV RNA genome regulates cap-independent IRES-mediated translation via YTHDC2 recognition.
Kim GW, Siddiqui A
Proceedings of the National Academy of Sciences of the United States of America (2021) 11810: . 202 003 IP; tested species: human

RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes.
Meng Y, Zhang Q, Wang K, Zhang X, Yang R, Bi K, Chen W, Diao H
Cell death & disease (2021) 128: 732. 202 003 IP; tested species: human

N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses.
Terajima H, Lu M, Zhang L, Cui Q, Shi Y, Li J, He C
PLoS biology (2021) 197: e3001292. 202 003 IP; tested species: human

TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2.
Cen S, Li J, Cai Z, Pan Y, Sun Z, Li Z, Ye G, Zheng G, Li M, Liu W, Yu W, et al.
EBioMedicine (2020) 54: 102722. 202 003 IP; tested species: human

METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Zhang C, Chen L, Peng D, Jiang A, He Y, Zeng Y, Xie C, Zhou H, Luo X, Liu H, Chen L, et al.
Molecular cell (2020) : . 202 003 IP, ICC; tested species: human

Alteration of N6-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy.
Li X, Fan X, Yin X, Liu H, Yang Y
Epigenomics (2020) : . 202 003 IP; tested species: mouse

m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.
Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, et al.
Immunity (2020) : . 202 003 IP; tested species: mouse

Deoxycholic acid modulates the progression of gallbladder cancer through N6-methyladenosine-dependent microRNA maturation.
Lin R, Zhan M, Yang L, Wang H, Shen H, Huang S, Huang X, Xu S, Zhang Z, Li W, Liu Q, et al.
Oncogene (2020) : . 202 003 IP; tested species: human

Dynamic landscape and evolution of m6A methylation in human.
Zhang H, Shi X, Huang T, Zhao X, Chen W, Gu N, Zhang R
Nucleic acids research (2020) : . 202 003 IP; tested species: human

Antibody-free enzyme-assisted chemical approach for detection of N6-methyladenosine.
Wang Y, Xiao Y, Dong S, Yu Q, Jia G
Nature chemical biology (2020) : . 202 003 IP; tested species: human,mouse

Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration.
Wang X, Chen N, Du Z, Ling Z, Zhang P, Yang J, Khaleel M, Khoury AN, Li J, Li S, Huang H, et al.
Epigenomics (2020) : . 202 003 IP; tested species: rat

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification.
Parker MT, Knop K, Sherwood AV, Schurch NJ, Mackinnon K, Gould PD, Hall AJ, Barton GJ, Simpson GG
eLife (2020) 9: . 202 003 IP

Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver.
Jabs S, Biton A, Bécavin C, Nahori MA, Ghozlane A, Pagliuso A, Spanò G, Guérineau V, Touboul D, Giai Gianetto Q, Chaze T, et al.
Nature communications (2020) 111: 1344. 202 003 IP; tested species: mouse

Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification.
Yoneda R, Ueda N, Uranishi K, Hirasaki M, Kurokawa R
The Journal of biological chemistry (2020) : . 202 003 IP; tested species: human

METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway.
Yang DD, Chen ZH, Yu K, Lu JH, Wu QN, Wang Y, Ju HQ, Xu RH, Liu ZX, Zeng ZL
Frontiers in oncology (2020) 10: 115. 202 003 IP; tested species: human

SFPQ Is an FTO-Binding Protein that Facilitates the Demethylation Substrate Preference.
Song H, Wang Y, Wang R, Zhang X, Liu Y, Jia G, Chen PR
Cell chemical biology (2020) : . 202 003 IP; tested species: human

Transcriptome-wide map of m6A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension.
Su H, Wang G, Wu L, Ma X, Ying K, Zhang R
BMC genomics (2020) 211: 39. 202 003 IP; tested species: rat

Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury.
Zhao TX, Wang JK, Shen LJ, Long CL, Liu B, Wei Y, Han LD, Wei YX, Wu SD, Wei GH
Environmental pollution (Barking, Essex : 1987) (2020) 259: 113911. 202 003 IP; tested species: rat

Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing.
Zhang Z, Wang Q, Zhang M, Zhang W, Zhao L, Yang C, Wang B, Jiang K, Ye Y, Shen Z, Wang S, et al.
Epigenetics (2020) : 1-11. 202 003 IP; tested species: human

Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.
Rong B, Zhang Q, Wan J, Xing S, Dai R, Li Y, Cai J, Xie J, Song Y, Chen J, Zhang L, et al.
Cell reports (2020) 3312: 108544. 202 003 IP; tested species: human

Zbtb7b suppresses aseptic inflammation by regulating m6A modification of IL6 mRNA.
Zhao J, Han DX, Wang CB, Wang XL
Biochemical and biophysical research communications (2020) 5301: 336-341. 202 003 IP; tested species: human

METTL14 regulates M6A methylation-modified primary miR-19a to promote cardiovascular endothelial cell proliferation and invasion.
Zhang BY, Han L, Tang YF, Zhang GX, Fan XL, Zhang JJ, Xue Q, Xu ZY
European review for medical and pharmacological sciences (2020) 2412: 7015-7023. 202 003 IP; tested species: human

Integrated analysis of the transcriptome-wide m6A methylome in preeclampsia and healthy control placentas.
Wang J, Gao F, Zhao X, Cai Y, Jin H
PeerJ (2020) 8: e9880. 202 003 IP; tested species: human

Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W, et al.
Science advances (2020) 634: eaba0647. 202 003 IP; tested species: human

A defined N6-methyladenosine (m6A) profile conferred by METTL3 regulates muscle stem cell/myoblast state transitions.
Gheller BJ, Blum JE, Fong EHH, Malysheva OV, Cosgrove BD, Thalacker-Mercer AE
Cell death discovery (2020) 6: 95. 202 003 IP; tested species: mouse

N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
Abakir A, Giles TC, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Li M, Eleftheriou M, Crutchley J, Flatt L, et al.
Nature genetics (2020) 521: 48-55. 202 003 IP, ICC; tested species: mouse

TRADES: Targeted RNA Demethylation by SunTag System.
Mo J, Chen Z, Qin S, Li S, Liu C, Zhang L, Ran R, Kong Y, Wang F, Liu S, Zhou Y, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2020) 719: 2001402. 202 003 IP; tested species: human

Identification and functional annotation of m6A methylation modification in granulosa cells during antral follicle development in pigs.
Cao Z, Zhang D, Wang Y, Tong X, Avalos LFC, Khan IM, Gao D, Xu T, Zhang L, G Knott J, Zhang Y, et al.
Animal reproduction science (2020) 219: 106510. 202 003 IP; tested species: pig

Joint analysis of lncRNA m6A methylome and lncRNA/mRNA expression profiles in gastric cancer.
Lv Z, Sun L, Xu Q, Xing C, Yuan Y
Cancer cell international (2020) 20: 464. 202 003 IP; tested species: human

METTL3 contributes to renal ischemia-reperfusion injury by regulating Foxd1 methylation.
Meng F, Liu Y, Chen Q, Ma Q, Gu S, Cui R, Cao R, Zhao M
American journal of physiology. Renal physiology (2020) : . 202 003 IP; tested species: rat

m6A RNA modification modulates PI3K/Akt/mTOR signal pathway in Gastrointestinal Cancer.
Zhao Q, Zhao Y, Hu W, Zhang Y, Wu X, Lu J, Li M, Li W, Wu W, Wang J, Du F, et al.
Theranostics (2020) 1021: 9528-9543. 202 003 IP; tested species: human

Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP.
Kim B, Arcos S, Rothamel K, Jian J, Rose KL, McDonald WH, Bian Y, Reasoner S, Barrows NJ, Bradrick S, Garcia-Blanco MA, et al.
Molecular cell (2020) 784: 624-640.e7. 202 003 IP; tested species: human

The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues.
Pandey RR, Delfino E, Homolka D, Roithova A, Chen KM, Li L, Franco G, Vågbø CB, Taillebourg E, Fauvarque MO, Pillai RS, et al.
Cell reports (2020) 327: 108038. 202 003 IP; tested species: mouse

Profiling of RNA N6-methyladenosine methylation during follicle selection in chicken ovary.
Fan Y, Zhang C, Zhu G
Poultry science (2019) : . 202 003 IP; tested species: chicken

The subunit of RNA N6-methyladenosine methyltransferase OsFIP regulates early degeneration of microspores in rice.
Zhang F, Zhang YC, Liao JY, Yu Y, Zhou YF, Feng YZ, Yang YW, Lei MQ, Bai M, Wu H, Chen YQ, et al.
PLoS genetics (2019) 155: e1008120. 202 003 IP

The m6A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants.
Pontier D, Picart C, El Baidouri M, Roudier F, Xu T, Lahmy S, Llauro C, Azevedo J, Laudié M, Attina A, Hirtz C, et al.
Life science alliance (2019) 23: . 202 003 IP

m6A modification of a 3' UTR site reduces RME1 mRNA levels to promote meiosis.
Bushkin GG, Pincus D, Morgan JT, Richardson K, Lewis C, Chan SH, Bartel DP, Fink GR
Nature communications (2019) 101: 3414. 202 003 IP; tested species: fission yeast

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma.
Li T, Hu PS, Zuo Z, Lin JF, Li X, Wu QN, Chen ZH, Zeng ZL, Wang F, Zheng J, Chen D, et al.
Molecular cancer (2019) 181: 112. 202 003 IP; tested species: human

Genome-wide identification of mRNA 5-methylcytosine in mammals.
Huang T, Chen W, Liu J, Gu N, Zhang R
Nature structural & molecular biology (2019) 265: 380-388. 202 003 IP; tested species: human

Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling.
Garcia-Campos MA, Edelheit S, Toth U, Safra M, Shachar R, Viukov S, Winkler R, Nir R, Lasman L, Brandis A, Hanna JH, et al.
Cell (2019) : . 202 003 IP; tested species: human,mouse

Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, Li S, Tan L, Mai D, Li G, Pan L, et al.
Nature communications (2019) 101: 1858. 202 003 IP; tested species: human,mouse

Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice.
Wang Y, Mao J, Wang X, Lin Y, Hou G, Zhu J, Xie B
Epigenomics (2019) : . 202 003 IP; tested species: mouse

The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.
Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, Chen M, Li D, Han P, Ji SJ
Nucleic acids research (2019) : . 202 003 IP; tested species: mouse

FTO controls reversible m6Am RNA methylation during snRNA biogenesis.
Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, et al.
Nature chemical biology (2019) : . 202 003 IP; tested species: mouse

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network.
Cheng M, Sheng L, Gao Q, Xiong Q, Zhang H, Wu M, Liang Y, Zhu F, Zhang Y, Zhang X, Yuan Q, et al.
Oncogene (2019) : . 202 003 IP; tested species: human,mouse

Single-molecule sequencing detection of N6-methyladenine in microbial reference materials.
McIntyre ABR, Alexander N, Grigorev K, Bezdan D, Sichtig H, Chiu CY, Mason CE
Nature communications (2019) 101: 579. 202 003 IP; tested species: e. coli

RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening.
Zhou L, Tian S, Qin G
Genome biology (2019) 201: 156. 202 003 IP

YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, Shen Q, Xu P, Zeng L, Zhou Y, Huang Y, et al.
Nature communications (2019) 101: 4892. 202 003 IP; tested species: mouse

N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer.
Jin H, Ying X, Que B, Wang X, Chao Y, Zhang H, Yuan Z, Qi D, Lin S, Min W, Yang M, et al.
EBioMedicine (2019) : . 202 003 IP; tested species: mouse

The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs.
Hsu PJ, Shi H, Zhu AC, Lu Z, Miller N, Edens BM, Ma YC, He C
The Journal of biological chemistry (2019) : . 202 003 IP; tested species: mouse

m6A Methylation Analysis of Differentially Expressed Genes in Skin Tissues of Coarse and Fine Type Liaoning Cashmere Goats.
Wang Y, Zheng Y, Guo D, Zhang X, Guo S, Hui T, Yue C, Sun J, Guo S, Bai Z, Cai W, et al.
Frontiers in genetics (2019) 10: 1318. 202 003 IP

Distinct m6A methylome profiles in poly(A) RNA from Xenopus laevis testis and that treated with atrazine.
Sai L, Li Y, Zhang Y, Zhang J, Qu B, Guo Q, Han M, Jia Q, Yu G, Li K, Bo C, et al.
Chemosphere (2019) 245: 125631. 202 003 IP; tested species: frog

m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma.
Liu L, Wang J, Sun G, Wu Q, Ma J, Zhang X, Huang N, Bian Z, Gu S, Xu M, Yin M, et al.
Molecular cancer (2019) 181: 188. 202 003 IP; tested species: human

Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication.
Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C
Plant physiology (2019) : . 202 003 Dot blot, IP

m6A RNA modification modulates gene expression and cancer-related pathways in clear cell renal cell carcinoma.
Chen Y, Zhou C, Sun Y, He X, Xue D
Epigenomics (2019) : . 202 003 IP; tested species: human

Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes.
Koh CWQ, Goh YT, Goh WSS
Nature communications (2019) 101: 5636. 202 003 IP; tested species: human

Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.
Berulava T, Buchholz E, Elerdashvili V, Pena T, Islam MR, Lbik D, Mohamed BA, Renner A, von Lewinski D, Sacherer M, Bohnsack KE, et al.
European journal of heart failure (2019) : . 202 003 IP; tested species: human

m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation.
Jia R, Chai P, Wang S, Sun B, Xu Y, Yang Y, Ge S, Jia R, Yang YG, Fan X
Molecular cancer (2019) 181: 161. 202 003 IP; tested species: human

TNF-α suppresses sweat gland differentiation of MSCs by reducing FTO-mediated m6A-demethylation of Nanog mRNA.
Wang Y, Wang R, Yao B, Hu T, Li Z, Liu Y, Cui X, Cheng L, Song W, Huang S, Fu X, et al.
Science China. Life sciences (2019) : . 202 003 IP; tested species: mouse

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, Lin J
Molecular and cellular biochemistry (2019) : . 202 003 IP; tested species: human

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.
Chen RX, Chen X, Xia LP, Zhang JX, Pan ZZ, Ma XD, Han K, Chen JW, Judde JG, Deas O, Wang F, et al.
Nature communications (2019) 101: 4695. 202 003 IP; tested species: human

N6-Methyladenosine Modification Controls Circular RNA Immunity.
Chen YG, Chen R, Ahmad S, Verma R, Kasturi SP, Amaya L, Broughton JP, Kim J, Cadena C, Pulendran B, Hur S, et al.
Molecular cell (2019) : . 202 003 IP; tested species: mouse

Distinct methylation levels of mature microRNAs in gastrointestinal cancers.
Konno M, Koseki J, Asai A, Yamagata A, Shimamura T, Motooka D, Okuzaki D, Kawamoto K, Mizushima T, Eguchi H, Takiguchi S, et al.
Nature communications (2019) 101: 3888. 202 003 IP; tested species: mouse

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, et al.
Genes & development (2018) 325-6: 415-429. 202 003 IP; tested species: mouse

Refined RIP-seq protocol for epitranscriptome analysis with low input materials.
Zeng Y, Wang S, Gao S, Soares F, Ahmed M, Guo H, Wang M, Hua JT, Guan J, Moran MF, Tsao MS, et al.
PLoS biology (2018) 169: e2006092. 202 003 IP; tested species: human

Identification and analysis of adenine N6-methylation sites in the rice genome.
Zhou C, Wang C, Liu H, Zhou Q, Liu Q, Guo Y, Peng T, Song J, Zhang J, Chen L, Zhao Y, et al.
Nature plants (2018) 48: 554-563. 202 003 IP

Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion.
Li Z, Qian P, Shao W, Shi H, He XC, Gogol M, Yu Z, Wang Y, Qi M, Zhu Y, Perry JM, et al.
Cell research (2018) : . 202 003 IP; tested species: mouse

Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
Koranda JL, Dore L, Shi H, Patel MJ, Vaasjo LO, Rao MN, Chen K, Lu Z, Yi Y, Chi W, He C, et al.
Neuron (2018) 992: 283-292.e5. 202 003 IP; tested species: mouse

METTL3-mediated m6A modification is required for cerebellar development.
Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, et al.
PLoS biology (2018) 166: e2004880. 202 003 IP; tested species: mouse

Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, et al.
Molecular cell (2018) 696: 1028-1038.e6. 202 003 IP; tested species: mouse

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function.
Du Y, Hou G, Zhang H, Dou J, He J, Guo Y, Li L, Chen R, Wang Y, Deng R, Huang J, et al.
Nucleic acids research (2018) : . 202 003 IP; tested species: human

N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential.
Yang D, Qiao J, Wang G, Lan Y, Li G, Guo X, Xi J, Ye D, Zhu S, Chen W, Jia W, et al.
Nucleic acids research (2018) : . 202 003 IP; tested species: mouse

Viral and cellular N6-methyladenosine and N6,2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle.
Tan B, Liu H, Zhang S, da Silva SR, Zhang L, Meng J, Cui X, Yuan H, Sorel O, Zhang SW, Huang Y, et al.
Nature microbiology (2018) 31: 108-120. 202 003 IP

Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, et al.
Neuron (2018) 972: 313-325.e6. 202 003 IP; tested species: mouse

FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications.
Martin Carli JF, LeDuc CA, Zhang Y, Stratigopoulos G, Leibel RL
Journal of lipid research (2018) 598: 1446-1460. 202 003 IP; tested species: mouse

mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes.
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, Liu Q, Shi H, Feng J, Wang Y
International journal of obesity (2005) (2018) : . 202 003 IP; tested species: pig

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.
Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, et al.
Cell stem cell (2018) 222: 191-205.e9. 202 003 IP

Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mendel M, Chen KM, Homolka D, Gos P, Pandey RR, McCarthy AA, Pillai RS
Molecular cell (2018) : . 202 003 IP; tested species: mouse

MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism.
Jiang Q, Sun B, Liu Q, Cai M, Wu R, Wang F, Yao Y, Wang Y, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2018) : fj201801393RRR. 202 003 IP; tested species: pig

RNA Modification Level Estimation with pulseR.
Boileau E, Dieterich C
Genes (2018) 912: . 202 003 IP; tested species: human

N6-Methyladenosine Inhibits Local Ribonucleolytic Cleavage to Stabilize mRNAs in Arabidopsis.
Anderson SJ, Kramer MC, Gosai SJ, Yu X, Vandivier LE, Nelson ADL, Anderson ZD, Beilstein MA, Fray RG, Lyons E, Gregory BD, et al.
Cell reports (2018) 255: 1146-1157.e3. 202 003 IP

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
Tsai K, Courtney DG, Cullen BR
PLoS pathogens (2018) 142: e1006919. 202 003 IP

N6-Methyladenine DNA Modification in the Human Genome.
Xiao CL, Zhu S, He M, Chen , Zhang Q, Chen Y, Yu G, Liu J, Xie SQ, Luo F, Liang Z, et al.
Molecular cell (2018) 712: 306-318.e7. 202 003 IP; tested species: human

The Role of m6A/m-RNA Methylation in Stress Response Regulation.
Engel M, Eggert C, Kaplick PM, Eder M, Röh S, Tietze L, Namendorf C, Arloth J, Weber P, Rex-Haffner M, Geula S, et al.
Neuron (2018) 992: 389-403.e9. 202 003 IP; tested species: mouse

Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome.
Koh CWQ, Goh YT, Toh JDW, Neo SP, Ng SB, Gunaratne J, Gao YG, Quake SR, Burkholder WF, Goh WSS
Nucleic acids research (2018) : . 202 003 IP; tested species: human

N6-methyldeoxyadenosine directs nucleosome positioning in Tetrahymena DNA.
Luo GZ, Hao Z, Luo L, Shen M, Sparvoli D, Zheng Y, Zhang Z, Weng X, Chen K, Cui Q, Turkewitz AP, et al.
Genome biology (2018) 191: 200. 202 003 IP

Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.
Wu Y, Xie L, Wang M, Xiong Q, Guo Y, Liang Y, Li J, Sheng R, Deng P, Wang Y, Zheng R, et al.
Nature communications (2018) 91: 4772. 202 003 IP; tested species: mouse

Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
Zhong X, Yu J, Frazier K, Weng X, Li Y, Cham CM, Dolan K, Zhu X, Hubert N, Tao Y, Lin F, et al.
Cell reports (2018) 257: 1816-1828.e4. 202 003 IP; tested species: mouse

The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation.
Kudou K, Komatsu T, Nogami J, Maehara K, Harada A, Saeki H, Oki E, Maehara Y, Ohkawa Y
Open biology (2017) 79: . 202 003 IP

Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.
Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, et al.
Cell (2017) 1714: 877-889.e17. 202 003 IP; tested species: human

m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.
Zhang S, Zhao BS, Zhou A, Lin K, Zheng S, Lu Z, Chen Y, Sulman EP, Xie K, Bögler O, Majumder S, et al.
Cancer cell (2017) 314: 591-606.e6. 202 003 IP; tested species: human

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.
Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, et al.
Molecular cell (2017) 661: 22-37.e9. 202 003 IP; tested species: mouse

The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.
Pendleton KE, Chen B, Liu K, Hunter OV, Xie Y, Tu BP, Conrad NK
Cell (2017) 1695: 824-835.e14. 202 003 IP; tested species: human

Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs.
Zhou C, Molinie B, Daneshvar K, Pondick JV, Wang J, Van Wittenberghe N, Xing Y, Giallourakis CC, Mullen AC
Cell reports (2017) 209: 2262-2276. 202 003 IP

m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome.
Molinie B, Wang J, Lim KS, Hillebrand R, Lu ZX, Van Wittenberghe N, Howard BD, Daneshvar K, Mullen AC, Dedon P, Xing Y, et al.
Nature methods (2016) 138: 692-8. 202 003 IP

Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation.
Koziol MJ, Bradshaw CR, Allen GE, Costa AS, Frezza C
Bio-protocol (2016) 621: . 202 003 IP

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications.
Koziol MJ, Bradshaw CR, Allen GE, Costa ASH, Frezza C, Gurdon JB
Nature structural & molecular biology (2016) 231: 24-30. 202 003 IP

The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.
Lin S, Choe J, Du P, Triboulet R, Gregory RI
Molecular cell (2016) 623: 335-345. 202 003 IP; tested species: human

Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
Liu J, Zhu Y, Luo GZ, Wang X, Yue Y, Wang X, Zong X, Chen K, Yin H, Fu Y, Han D, et al.
Nature communications (2016) 7: 13052. 202 003 IP, ICC; tested species: zebrafish,pig

Decomposition of RNA methylome reveals co-methylation patterns induced by latent enzymatic regulators of the epitranscriptome.
Liu L, Zhang SW, Zhang YC, Liu H, Zhang L, Chen R, Huang Y, Meng J
Molecular bioSystems (2015) 111: 262-74. 202 003 IP

N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas.
Fu Y, Luo GZ, Chen K, Deng X, Yu M, Han D, Hao Z, Liu J, Lu X, Dore LC, Weng X, et al.
Cell (2015) 1614: 879-892. 202 003 IP

N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T
Nature (2015) 5187540: 560-4. 202 003 IP

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.
Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour AA, Kol N, Salmon-Divon M, Hershkovitz V, Peer E, Mor N, Manor YS, Ben-Haim MS, et al.
Science (New York, N.Y.) (2015) 3476225: 1002-6. 202 003 IP

Widespread occurrence of N6-methyladenosine in bacterial mRNA.
Deng X, Chen K, Luo GZ, Weng X, Ji Q, Zhou T, He C
Nucleic acids research (2015) 4313: 6557-67. 202 003 IP; tested species: e. coli

N6-adenosine methylation in MiRNAs.
Berulava T, Rahmann S, Rademacher K, Klein-Hitpass L, Horsthemke B
PloS one (2015) 102: e0118438. 202 003 IP

Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.
Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET
Journal of the American Chemical Society (2015) 1375: 2107-15. 202 003 IP

DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 Dot blot, IP

N6-methyladenosine marks primary microRNAs for processing.
Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF
Nature (2015) 5197544: 482-5. 202 003 IP

Unique features of the m6A methylome in Arabidopsis thaliana.
Luo GZ, MacQueen A, Zheng G, Duan H, Dore LC, Lu Z, Liu J, Chen K, Jia G, Bergelson J, He C, et al.
Nature communications (2014) 5: 5630. 202 003 IP

Transcriptome-wide N⁶-methyladenosine profiling of rice callus and leaf reveals the presence of tissue-specific competitors involved in selective mRNA modification.
Li Y, Wang X, Li C, Hu S, Yu J, Song S
RNA biology (2014) 119: 1180-8. 202 003 IP

Transcriptome-wide mapping of N(6)-methyladenosine by m(6)A-seq based on immunocapturing and massively parallel sequencing.
Dominissini D, Moshitch-Moshkovitz S, Salmon-Divon M, Amariglio N, Rechavi G
Nature protocols (2013) 81: 176-89. 202 003 IP

DNA binding of the cell cycle transcriptional regulator GcrA depends on N6-adenosine methylation in Caulobacter crescentus and other Alphaproteobacteria.
Fioravanti A, Fumeaux C, Mohapatra SS, Bompard C, Brilli M, Frandi A, Castric V, Villeret V, Viollier PH, Biondi EG
PLoS genetics (2013) 95: e1003541. 202 003 IP

A link between FTO, ghrelin, and impaired brain food-cue responsivity.
Karra E, O'Daly OG, Choudhury AI, Yousseif A, Millership S, Neary MT, Scott WR, Chandarana K, Manning S, Hess ME, Iwakura H, et al.
The Journal of clinical investigation (2013) 1238: 3539-51. 202 003 IP

DamIP: using mutant DNA adenine methyltransferase to study DNA-protein interactions in vivo.
Xiao R, Moore DD
Current protocols in molecular biology (2011) Chapter 21: Unit21.21. 202 003 IP

Antibodies specific for N6-methyladenosine react with intact snRNPs U2 and U4/U6.
Bringmann P, Lührmann R
FEBS letters (1987) 2132: 309-15. 202 003 IP

A distinct subclade of AlkB family demethylases in ciliates safeguards the positional fidelity of eukaryotic N6-methyladenine (6mA).
Niu J, Yu H, Liu Y, Nie L, Nan B, Zhang W, Song N, Rong S, Zhou D, Gao S
Proceedings of the National Academy of Sciences of the United States of America (2026) 12310: e2526398123. 202 003 ICC

N6-methyladenosine (m6A) dysregulation contributes to network excitability in temporal lobe epilepsy.
Mathoux J, Wilson MM, Srinivas S, Litovskich G, Villalba Benito L, Tran C, Kesavan J, Harnett A, Auer T, Sanz-Rodriguez A, Kh A E Alkhayyat M, et al.
JCI insight (2025) 1014: . 202 003 ICC, MeRIP; tested species: human,mouse

Multichrome encoding-based multiplexed, spatially resolved imaging reveals single-cell RNA epigenetic modifications heterogeneity.
Mao D, Tang X, Zhang R, Hu S, Gou H, Zhang P, Li W, Pan Q, Shen B, Zhu X
Nature communications (2025) 161: 958. 202 003 ICC, IHC, MeRIP; tested species: human,mouse

Methyl-dependent auto-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila.
Duan L, Li H, Ju A, Zhang Z, Niu J, Zhang Y, Diao J, Liu Y, Song N, Ma H, Kataoka K, et al.
Nucleic acids research (2025) 533: . 202 003 ICC, MeRIP

Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage response.
Gonzalez-Leal C, Cai J, de Groot BAFJ, Wegerer A, Preisser J, Luijsterburg MS, Ladurner AG
Nucleic acids research (2025) 537: . 202 003 ICC; tested species: human

N6-methyladenosine in DNA promotes genome stability.
Conti BA, Novikov L, Tong D, Xiang Q, Vigil S, McLellan TJ, Nguyen C, De La Cruz N, Veettil RT, Pradhan P, Sahasrabudhe P, et al.
eLife (2025) 13: . 202 003 ICC; tested species: human

The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids.
Sun Y, Zhang H, Li S, Zhang J, Lyu B, Kang L, Teng X, Yin M, Peng W, Wang J, Chu Z, et al.
Cell reports (2025) 4410: 116438. 202 003 ICC; tested species: human

Multiplexed In Situ Imaging of Site-Specific m6A Methylation with Proximity Hybridization Followed by Primer Exchange Amplification (m6A-PHPEA).
Song M, Wang J, Hou J, Fu T, Feng Y, Lv W, Ge F, Peng R, Han D, Tan W
ACS nano (2024) 1840: 27537-27546. 202 003 ICC; tested species: human

Mitochondrial epigenetics brings new perspectives on doubly uniparental inheritance in bivalves.
Leroux É, Khorami HH, Angers A, Angers B, Breton S
Scientific reports (2024) 141: 31544. 202 003 ICC

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions.
Park J, Wu Y, Shao W, Gendron TF, van der Spek SJF, Sultanakhmetov G, Basu A, Castellanos Otero P, Jones CJ, Jansen-West K, Daughrity LM, et al.
Cell reports (2023) 428: 112822. 202 003 ICC; tested species: human

Potential role of N6-adenine DNA methylation in alternative splicing and endosymbiosis in Paramecium bursaria.
Pan B, Ye F, Li T, Wei F, Warren A, Wang Y, Gao S
iScience (2023) 265: 106676. 202 003 ICC, MeRIP

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, et al.
Molecular cell (2021) 8120: 4209-4227.e12. 202 003 ICC, IHC; tested species: human,mouse

METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.
Zhao F, Xu Y, Gao S, Qin L, Austria Q, Siedlak SL, Pajdzik K, Dai Q, He C, Wang W, O'Donnell JM, et al.
Molecular neurodegeneration (2021) 161: 70. 202 003 IHC-P (FFPE), ICC; tested species: human,mouse,rat

Treatment of cancer cells with Lapatinib negatively regulates general translation and induces stress granules formation.
Adjibade P, Simoneau B, Ledoux N, Gauthier WN, Nkurunziza M, Khandjian EW, Mazroui R
PloS one (2020) 155: e0231894. 202 003 ICC; tested species: human

A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription.
Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, Pan B, Qiao Y, Liu Y, Gao S
Nucleic acids research (2019) : . 202 003 ICC

Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development.
Kwon J, Jo YJ, Namgoong S, Kim NH
Scientific reports (2019) 91: 8640. 202 003 ICC; tested species: mouse

Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals.
de Wit E, Greil F, van Steensel B
Genome research (2005) 159: 1265-73. 202 003 ICC; tested species: drosophila

Mitochondrial DNA 6 mA methylation by METTL4 drives neuroinflammation via cGAS-STING activation in vascular cognitive impairment.
Gong Z, Chen Z, Sang S, Yang L, Qin H, Li Q, Jia Y
Free radical biology & medicine (2026) 246: 1-16. 202 003 IHC; tested species: rat

Drugs targeting synaptic RNA m6A methylation regulate synaptic transmission and plasticity in the rat hippocampus.
Keskinen R, Rhee JK, Teino I, Renzi B, Saarma M, Lauri SE
Experimental neurology (2026) 402: 115802. 202 003 IHC; tested species: rat

A skin-hypothalamus axis couples heat stress and metabolic dysfunction.
Zhou HY, Feng X, Wen J, Xiao Y, Wang LW, Chen LY, Xie GQ, Zhao JJ, Huang Y, Luo XH
Cell (2026) : . 202 003 IHC; tested species: mouse

Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications.
Chen Y, Zhu H, Guo F, Wang L, Zhang W, Liu R, Zhang X, Dai X
Clinical epigenetics (2025) 171: 20. 202 003 IHC; tested species: mouse

Emerging role of N6-methyladenosine (m6A) epitranscriptomic changes in adult anxiety after adolescent alcohol exposure.
Malovic E, Tandukar J, Zhang H, Venkareddy LK, Gao R, Pandey SC
Neuropharmacology (2025) 285: 110777. 202 003 IHC; tested species: rat

Ythdc1-p300-Klf5 Complex-Mediated Golgi Dysfunction Promotes Aortic Aneurysm.
Wang WL, Song ZX, Bu SM, Liu YM, Li Q, Zhang WX, Sun XR, Zhang X, Xiao YX, Bo D, Miao XB, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025) : e12116. 202 003 IHC; tested species: human

Astrocytic Mettl14 depletion enhances cognitive function by attenuating astrogliosis via the DUSP1/MAPK pathway in APP/PS1 mice: targeting neuroinflammation in Alzheimer's disease.
Teng Y, Xu J, He S, Yi J, Li M, Tang Q, Chen X, Wei F, Liu Y, Jiang H, Xiang Y, et al.
Molecular psychiatry (2025) : . 202 003 IHC; tested species: mouse

Hepatitis B Virus-mediated m6A demethylation increases hepatocellular carcinoma stemness and immune escape.
Meng Y, Shu Z, Wang X, Hong L, Wang B, Jiang J, He K, Cao Q, Shi F, Wang H, Gong L, et al.
Molecular cancer research : MCR (2024) : . 202 003 IHC, MeRIP; tested species: human

Arginase 1 does not affect RNA m6A methylation in mouse fetal lung.
Sui X, Sui Y, Long P, Wang Y, Chen Y, Zhai W, Gao L
Birth defects research (2024) 1162: e2318. 202 003 IHC; tested species: mouse

m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.
Niu F, Che P, Yang Z, Zhang J, Yang L, Zhuang M, Ou X, Ji SJ
iScience (2022) 259: 104908. 202 003 IHC; tested species: mouse

Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington's disease mice.
Pupak A, Singh A, Sancho-Balsells A, Alcalá-Vida R, Espina M, Giralt A, Martí E, Ørom UAV, Ginés S, Brito V
Cellular and molecular life sciences : CMLS (2022) 798: 416. 202 003 IHC; tested species: mouse

Drosophila Tet is required for maintaining glial homeostasis in developing and adult fly brains.
Frey F, Sandakly J, Ghannam M, Doueiry C, Hugosson F, Berlandi J, Ismail JN, Gayden T, Hasselblatt M, Jabado N, Shirinian M, et al.
eNeuro (2022) : . 202 003 IHC; tested species: drosophila

202 003 IHC; tested species: mouse

ALKBH5-mediated m6A regulates the alternative splicing events of SRSF10 in ovarian cancer.
Li K, Pei Y, Dong X, Wu Y, Lou X, Li Y, Liang S, Wu Y, Xu D, Li B, Cui W, et al.
Cancer gene therapy (2025) 325: 584-594. 202 003 IHC-P (FFPE); tested species: human

METTL3-mediated N6-methyladenosine modification of LEPR is critical for fetal growth restriction.
Li D, Jiang J, Zhong Y, Luo M, Chen J, Li J, Chen X, Li M, Zhong M, Zhang Y
Placenta (2026) 175: 54-65. 202 003 MeRIP; tested species: human

Screening of M6a methylated genes associated with preovulatory follicle development in Bashang long-tailed chicken.
Duan X, Xie J, Yin S, Zhang L, Liu Y
Poultry science (2026) 1057: 106892. 202 003 MeRIP; tested species: chicken

Dysregulation of PCSK9 via m6A-dependent epitranscriptomic programs fosters hepatocellular carcinoma progression.
Wang WL, Yen CC, Yen CS, Huang YH, Huang HY, Chen JF, Liu YY, Wang ST, Liu YT, Hung MC, Yen CJ, et al.
Cancer letters (2026) 640: 218255. 202 003 MeRIP; tested species: human

YTHDF2-orchestrated m6A methylation of BECN1 induces Scoparone-mediated hepatic stellate cell ferroptosis to attenuate liver fibrosis.
Sun Y, Zhuang Y, Cheng K, Wei Y, Li M, Xuan J, Zheng S, Guo M, Zhang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology (2026) 153: 157912. 202 003 MeRIP; tested species: mouse

METTL3-mediated N6-methyladenosine modification of Dnajb1 modulates cardiomyocyte ferroptosis during myocardial infarction.
Zhang S, Xiang B, Zhao Y, Chen L, Meng D, Zhou X
Proceedings of the National Academy of Sciences of the United States of America (2026) 12310: e2529187123. 202 003 MeRIP; tested species: mouse

H3K18 lactylation promotes osteogenic differentiation of periodontal ligament stem cells via IGF2BP1/m6A/BMP2.
Wang Z, Weng B, Qian J, Guo H
Biochemical pharmacology (2026) 249: 117899. 202 003 MeRIP; tested species: mouse

Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.
Chakrabarty RP, Van Vranken JG, Aoi Y, Poor TA, McElroy GS, Vasan K, Soliman SHA, Iwanaszko M, Grant RA, Howard BC, Reczek CR, et al.
Nature (2026) : . 202 003 MeRIP; tested species: mouse

Cold storage delays peach fruit softening via m6A reader PpYTHDFE1 liquid-liquid phase separation-mediated degradation of cell wall-loosening transcript PpEXP3.
Wang H, Bian H, Wu X, Chen K, Grierson D, Zhang B
Molecular horticulture (2026) 61: . 202 003 MeRIP

m6A mRNA methylation initiated by METTL14 promotes STK11 translation and increases STK11 activity to induce anti-HER2 therapy resistance in breast cancer.
Yang F, Ma P, He Y, Li Y, Liang Y, Li W, Huang X, Sun C, Yan X, Hua Y, Gong J, et al.
Biochimica et biophysica acta. Molecular basis of disease (2026) 18721: 168029. 202 003 MeRIP; tested species: human

IGF2BP3 promotes gastric cancer progression by inhibiting ferroptosis through ETV4-mediated regulation of GCH1.
Li K, Wei H, Li F, Zheng Y, Zhou Y
Cancer biology & therapy (2026) 271: 2664967. 202 003 MeRIP; tested species: human

FTO-mediated m6A depletion drives prenatal prednisone exposure-induced cortical neurogenesis deficits and long-term anxiety-depression-like behaviors in offspring.
Qi C, Guo J, Zhu S, Liu K, Liu Y, Luo M, Jin X, Dai G, Yang P, Wang S, Chen X, et al.
Acta pharmaceutica Sinica. B (2026) 164: 2375-2395. 202 003 MeRIP; tested species: rat

RBM15 drives bladder cancer progression through YTHDF2-dependent m6A-mediated regulation of ZO2.
He Y, Gong Y, Wu Y, He S, Wang Y, Gao W, Tian T, Xu X, Zhou L, Shi Z, Han C, et al.
Journal of experimental & clinical cancer research : CR (2026) 451: . 202 003 MeRIP; tested species: human

M6A-dependent regulation of microRNAs from CKD stage 5 patients: insights from epigenetic modification analysis.
Yang Z, Liu F, Ye M, Yan Q, Zeng Z, Ma J, Li H, Ma H, Zhang X, Zhu X, Dai Y, et al.
Epigenetics (2026) 211: 2653962. 202 003 MeRIP; tested species: human

Histological and epigenetic alterations in vaginal relaxation syndrome: evidence from m6A-Seq, RNA-Seq, and animal models.
Cui D, Cui C, Yang M, Zhang L, Dai Y, Luo X
Folia morphologica (2026) 85: e01726037. 202 003 MeRIP; tested species: human,rat

Brain neuronal CG9593/ANGPTL4 activation mediates paternally acquired motor disorders.
Zhang J, Wei T, Xiong YW, Guan SZ, Zhou H, Fan LL, Nie YH, Yuan Z, Li H, Wang KW, Chang W, et al.
Science advances (2026) 1212: eaea8321. 202 003 MeRIP; tested species: human,mouse

Methyltransferase like 3 promotes thyroid folliculogenesis via coordinating cell differentiation and polarization.
Jiang R, Zhu Q, Zhang Z, He X, Liu Y, Kan R, He X, Guan H
Journal of translational internal medicine (2026) 141: 96-107. 202 003 MeRIP; tested species: human

PiR48444 inhibits MSC osteogenic differentiation and bone regeneration via targeting METTL7A/eIF4E-mediated BMP2 m6A methylation.
Zheng Z, Li X, Qin W, Yu S, Xu T, Cheng H, Xie W, Fu Z, Pan G, Zhang Y, Huang W, et al.
Communications biology (2026) 91: . 202 003 MeRIP; tested species: human

METTL3 Methylation Induces Decay of Endogenous Retroelement Transcripts to Promote Tumor Immune Evasion.
She X, Lan J, Zhang H, Lu G, Xu J, Zhang J, Zhan W, Feng S, Rao Z, Yu C, Han B, et al.
Cancer research (2026) : . 202 003 MeRIP; tested species: human

3'-Methoxypuerarin Ameliorates Myocardial Ischemia/Reperfusion-Induced Pyroptosis via Regulating IGF2BP1/m6A/NLRP3 Pathway.
Zhou H, Zhou H, Li C, Fatima S, Qiao L, Lu D, Li W
Antioxidants & redox signaling (2026) 441-3: 103-117. 202 003 MeRIP; tested species: rat

N6-methyladenosine (m6A) modification of TXNIP in 3'UTR instigates abdominal aorta aneurysm in mice.
Hantelys F, Yin W, Zou MH
iScience (2026) 292: 114630. 202 003 MeRIP; tested species: human

Fuzheng Shengbai Decoction Enhances Antitumor Immunity via YTHDC2-Dependent Stabilization of CLCA2 mRNA in Colorectal Cancer.
Wang Y, Zhao Y, Ding K, Zhang B, Li M, Chen J, Yuan W, Zheng Q, Fang M, Wang S
Journal of ethnopharmacology (2026) : 121280. 202 003 MeRIP; tested species: mouse

Subtype-Specific m6A circRNA Methylation Patterns Identify Epigenetic Biomarker Candidates of Potential Diagnostic and Prognostic Significance in Breast Cancer.
Qattan A, Alkhayal W, Suleman K, Al-Tweigeri T, Tulbah A
International journal of molecular sciences (2026) 271: . 202 003 MeRIP; tested species: human

Potyviruses recruit host eIF4A3 to block m6A-mediated RNA decay by steric hindrance of viral RNA methylation in plants.
Peng D, Dong L, Wang P, Zang L, Xie J, Wang H, Li X, Fan Z, Zhou T, Du K
Nucleic acids research (2026) 541: . 202 003 MeRIP

Periplocin and bufalin induce cardiotoxicity by regulating AMPK/SIRT1/PGC-1α pathway to inhibit energy metabolism and trigger autophagy.
Gao X, Zhang J, Lin Y, Tian K, Tu J, Wu Z, Lv X, Hu H, Liu X, Lin S, Zhu A, et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology (2026) 150: 157688. 202 003 MeRIP; tested species: rat

Betaine mediated m6A methylation: a strategy for improving tolerance in pepper seedlings to low temperature combined with low light stress.
Li N, Li J, Xie J, Rui W, Gao Y, Pu K, Zhang M, Wang T, Ma Y, Zhang J
International journal of biological macromolecules (2026) 344Pt 2: 150495. 202 003 MeRIP

The LkMTA2/LkMTB8-LkERF1-LkEXPA8 cascade regulates xylem cell expansion in larch.
Lyu Z, Xie Y, Zhang K, Han H, Zhang S, Sun X
The New phytologist (2026) 2503: 1535-1550. 202 003 MeRIP

Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability.
Zhao X, Wang X, Liu K, Fang Q, Wang C, Mei G, Qu L, Zhang J, Feng J, Yang W, Zhu J, et al.
PLoS pathogens (2026) 225: e1014007. 202 003 MeRIP; tested species: mouse

The YTHDC1-m6A-GADD45B axis promotes chondrogenesis of hPDLSCs via suppressing senescence through p53/p21 signalling pathway.
Tan D, Tao Q, Ye L, Long X, Ye Q, Li Q, Song J, Xiao J
International journal of oral science (2026) 181: . 202 003 MeRIP; tested species: human

Prevalence of N6-methyladenosine (m6A) in mycoplasma mRNA:Epitranscriptomic regulation in minimal genomes.
Zhang S, Zhang Y, Luo Y, Zhang S, Song Y, Li B, Zheng F, Gao P, Xu J, Chu Y
Microbial pathogenesis (2026) 210: 108127. 202 003 MeRIP

N6-methyladenosine reader YTHDF3-mediated Lcn2 mRNA stability promotes the hepatotoxicity of crizotinib.
Liu R, Liu H, Chen H, An K, Wei J, Zhang J, Du Y, Wang Y, Tian X
Toxicological sciences : an official journal of the Society of Toxicology (2026) 2091: . 202 003 MeRIP; tested species: human

N6-methyladenosine epitranscriptomic remodeling: Dynamic landscape and functional analysis of host RNA methylation induced by PRRSV infection.
Zhang M, Wen W, Wang W, Zhu Z, Li X
Veterinary microbiology (2026) 312: 110819. 202 003 MeRIP; tested species: monkey

Pseudane V alleviates ox-LDL-induced macrophage M1 polarization by inhibiting m6A modification of PPARGC1A.
Li T, Pang Q, Pan J, Gao Y, Huang Y, Tian W, Ran J, Zhu Z, Liu Y, Li K
Experimental cell research (2026) 4542: 114842. 202 003 MeRIP; tested species: human

circCNN2 drives endometrial cancer progression through ALKBH5/YTHDF2-mediated m6A regulation and miR-615-5p sponging.
Cai C, Peng X, Han Y, Zhu Y
Life sciences (2026) 385: 124118. 202 003 MeRIP; tested species: human

17-AAG promotes the degradation of HSP90 client METTL3 to suppress MYC RNA m6A modification and expression in colorectal cancer.
Meng H, Jalal M, Wang H, Wang Y, Feng Y, Zheng P, Liu X, Huang S
International journal of biological macromolecules (2026) 337Pt 1: 149421. 202 003 MeRIP; tested species: human

Shenqi Tiaoshen formula attenuates COPD through METTL16-dependent m6A regulation of MALT1-NF-κB.
Chen K, Xu B, Xue Q, Ma X, Tong J, Zhu J, Yang Q, Li Z
Journal of ethnopharmacology (2026) 358: 121036. 202 003 MeRIP; tested species: rat

FTO demethylates Cyclin E1/D1 mRNA and inhibits non-small cell lung cancer cell EMT and proliferation.
Sun Z, Shi L, Wang Y, Zhou Z, Liu J
Cellular signalling (2026) 145: 112615. 202 003 MeRIP; tested species: human

IGF2BP2 condensates stabilize DOK3 to negatively regulate inflammatory responses.
Chen J, Chen W, Shan X, Lu P, Sun Z, Chen S, Liu B, Wu C, Lu B
Journal of immunology (Baltimore, Md. : 1950) (2026) 2154: . 202 003 MeRIP; tested species: human

Hepatic Stellate Cell-Specific METTL3 Deficiency Promotes Hepatocellular Carcinoma Progression via BMP10-SMAD1/5/8 Signaling.
Yu S, Zhang Y, Li Y, Pan L, Liang X, Meng W, Dong S, Sun Y, Liu X, Ye L, Zhang Q, et al.
Cancer research communications (2026) 65: 1109-1122. 202 003 MeRIP; tested species: human

Neuronal YTHDF2 suppresses innate immune activation in Aβ pathology by promoting m6A-dependent decay of cytosolic mitochondrial mRNAs.
Pan W, Yang L, Zhang Y, Chen Y, Xu Y, Li Y, Fu Y, Ma C, Liu C, Li Q, Liu H, et al.
Science advances (2026) 1225: eadz0887. 202 003 MeRIP; tested species: mouse

Oleanolic acid modulates neuronal regeneration through KLF5-mediated FGF13 mRNA degradation to alleviate Alzheimer's disease-like cognitive dysfunction.
Ren D, Xu J, Xiao L, Zhang T, Li B, Li R, Zhu H
Journal of molecular medicine (Berlin, Germany) (2026) 1041: . 202 003 MeRIP; tested species: rat

Environmental cadmium drives placental senescence and fetal growth restriction via activating CLPP-dependent mitochondrial stress.
Pan R, Zhang J, Wu LL, Sun CF, Zhang XX, Wu YX, Yin XA, Luo YX, Liu ST, Bao ZJ, Chang W, et al.
Journal of hazardous materials (2026) 512: 142400. 202 003 MeRIP; tested species: human

HFPO-TA inhibits testosterone synthesis by triggering FTO-mediated m6A modification to drive NCOA4-associated ferroptosis.
Tian M, Gao H, Wu Y, Tian M, Cao H, Zhu L, Geng Y, Li G
Journal of hazardous materials (2026) 514: 142733. 202 003 MeRIP; tested species: mouse

G-quadruplex/m6A-regulated BCL2 pre-mRNA alternative splicing and comparative characterization of its two isoforms.
Yang C, Wu S, Wang H, Li G, Xing Y, Ma B, Shi J, Li D, Sui G
International journal of biological macromolecules (2026) 338Pt 1: 149670. 202 003 MeRIP; tested species: human

Diapause termination alters the m6A methylation profiles and regulates gene expression associated with early embryonic development in the silkworm (Bombyx mori).
Huang ZH, Yang JY, Hou CP, Liu SH, Li B, Wang J, Huang SJ, Xu JP
Journal of insect physiology (2026) 169: 104944. 202 003 MeRIP

m6A RNA modifications in neurosystem genes as early markers for osteoporosis with iron accumulation.
Liu B, Wang Y, Zheng M, Huang K, Qin J, Zhai Q, Xu Y
Molecular biology reports (2026) 531: . 202 003 MeRIP; tested species: mouse

Biomembrane-coated Nanoparticles Targeting circHIF1α Suppress Ovarian Cancer Metastasis and Cisplatin Resistance by Mediating System Xc⁻ Inactivation via SLC7A11/SLC3A2 to Induce Ferroptosis in Cancer Stem Cells.
Chang Y, Wang J, Ma L, Liu Y, Zhu Y, Yi Y, Zhang D, Zhao Z, Sun L, Song Y
International journal of biological sciences (2026) 2210: 5525-5547. 202 003 MeRIP; tested species: human

WTAP tetramer ensures m6A writer assembly and faithful mitosis.
Zhang S, Ye J, Zhang M, Cao J, Li Y, Hu R, Chen D, Li T, Chen J, Zhu W, Jiang W, et al.
EMBO reports (2026) : . 202 003 MeRIP; tested species: human

METTL3-regulated m6A modification modulates autophagy of placental mesenchymal stem/stromal cell by YTHDF3-mediated degradation of LncRNA GAS5 in preeclampsia.
Zhang Y, Wu D, Zou L, Cheng X, Liu X
Placenta (2026) 176: 31-42. 202 003 MeRIP; tested species: human

IGF2BP2/ISG15/c-Myc axis promotes the excessive proliferation of granulosa cells in polycystic ovary syndrome.
Han L, Miao H, Li N, Miao C
Molecular and cellular endocrinology (2026) 611: 112666. 202 003 MeRIP; tested species: human

Clinical and prognostic significance of m6A hypomethylation and IGF2BP3 overexpression in gastric cancer: an integrated epigenomic-transcriptomic analysis.
Hu X, Wang Z, Kou Y, Huang Y
Human genomics (2025) 191: 95. 202 003 MeRIP; tested species: human

Role of N6-methyladenosine methylation in transverse aortic constriction-induced cardiac fibrosis: insights from MeRIP-seq analysis.
Liu S, Liu H, Bai Q, Wei Z, Zhao P, Chen H, Song B, Yu C
Molecular biology reports (2025) 521: 850. 202 003 MeRIP; tested species: mouse

Analysis of Non-Coding RNAs and N6-Methyladenosine-Modified Genes in Response to flg22 in Grape Immunity.
Duan R, Feng Y, Zhang R, Lu W, Xie Q, Duan D
Plant biotechnology journal (2025) : . 202 003 MeRIP

Construction of RNA m6A profiles in liver tissue of mice in sepsis-induced liver injury based on m6A MeRIP-seq and RNA-seq.
Li L, Li P, He Y, Xu Z, Fan Y, Jia X, Liu Y, Qin L
European journal of medical research (2025) 301: 723. 202 003 MeRIP; tested species: mouse

Recessive epistasis of a synonymous mutation confers cucumber domestication through epitranscriptomic regulation.
Xin T, Zhang Z, Zhang Y, Li X, Wang S, Wang G, Li H, Wang B, Zhang M, Li W, Tian H, et al.
Cell (2025) : . 202 003 MeRIP

YTHDF2 alleviates the radioresistance of rectal cancer cells by targeting methylated MYC.
Fang Y, Shang S, Chen G, Chen D, Yu J
Journal of radiation research (2025) : . 202 003 MeRIP; tested species: human

The m6A demethylase FTO regulates TNF-α expression in human macrophages following Toxoplasma gondii infection.
Qin M, Gao N, Sun J, Lin S, Hu T, Liu X, Zhang R, Wang Y, Qiu J
PLoS neglected tropical diseases (2025) 197: e0013289. 202 003 MeRIP; tested species: human

FTO promotes breast cancer development via inhibiting CYP27B1 /1,25-dihydroxyvitamin D3 asis in m6A-dependent manner.
Qin Y, Zeng H, Dong Z, Zhu C, Bian Q, Zhai X, Tang H, Zhou F, Yang L, Zhang J
International journal of biological macromolecules (2025) 319Pt 3: 145464. 202 003 MeRIP; tested species: human

Cancer-associated fibroblasts-secreted lactate promotes RNA polymerase III subunit G-mediated epithelial-mesenchymal transition in non-small cell lung cancer by increasing m6A modification of zinc finger protein 384.
Li P, Yang X, Tang H, Zhou Z, Liu B
Journal of cell communication and signaling (2025) 193: e70037. 202 003 MeRIP; tested species: human

YTHDF3 recognizes DNA N6-methyladenine and recruits ALKBH1 for 6mA removal from genomic DNA.
Chen XH, Wang ZL, Yang J, Chen M, Zhao SY, Guo KX, Zheng X, Zhao Z, Chen X, Li J, Zhang MM, et al.
The EMBO journal (2025) : . 202 003 MeRIP; tested species: human

Stabilization of OLFML1 via m6A Reader IGF2BP3 Drives CSC Characteristics Through Hedgehog Pathway Activation in CRC.
Zhong Y, Liu J, Lin W, Peng T, Gao L, Shen L, Wang P, Hu Z, Long T, Li Z, Liu J, et al.
International journal of biological sciences (2025) 2110: 4334-4352. 202 003 MeRIP; tested species: human

WTAP-induced m6A Methylation of Atoh8 Promotes Cell Proliferation and Fibrosis in Diabetic Nephropathy.
Wang S, Zhang H, Fei B, Zhang M
Cell biochemistry and biophysics (2025) : . 202 003 MeRIP; tested species: mouse

Stage-specific requirement for METTL3-dependent m6A epitranscriptomic regulation during myogenesis.
Tan YY, Ou YW, Zuo Q, Luo Y, Chen WC, Chen WX, Zhi XW, Lin PW, Lu JX, Liu P, Liang SM, et al.
Communications biology (2025) 81: 1317. 202 003 MeRIP; tested species: mouse

Evolutionary insights and poly(I:C)-induced changes in expression and m6A modifications of il17ra and il17rc in Miichthysmiiuy.
Tian R, Geng S, Lv X, Li W, Xu T, Sun Y
Fish & shellfish immunology (2025) 162: 110343. 202 003 MeRIP

FTO Promotes Osteogenic Differentiation of Human BMSCs via Demethylation of TGFB2 m6A Modifications.
Li X, Chen W, Zhong W, Tan L, Deng K, Cao W, Zhu M, Wu A, Zhang Z, Hei Y, Jiang S, et al.
Oral diseases (2025) 318: 2505-2517. 202 003 MeRIP; tested species: human

Engineering a nano-drug delivery system to regulate m6A modification and enhance immunotherapy in gastric cancer.
Li Z, Zhang X, Liu C, Wu Y, Wen Y, Zheng R, Xu C, Tian J, Peng Q, Zheng X, Wang J, et al.
Acta biomaterialia (2025) 191: 412-427. 202 003 MeRIP; tested species: human

CTCF enhances pancreatic cancer progression via FLG-AS1-dependent epigenetic regulation and macrophage polarization.
Liu Y, Liu P, Duan S, Lin J, Qi W, Yu Z, Gao X, Sun X, Liu J, Lin J, Zhai S, et al.
Cell death and differentiation (2025) 324: 745-762. 202 003 MeRIP; tested species: human

Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development.
Liu Y, Lin J, Yu Z, Li X, Lv X, Liu P, Sun X, Zhang Z, Gao X, Sun K, Li D, et al.
Cell metabolism (2025) 379: 1907-1925.e14. 202 003 MeRIP; tested species: human,mouse

The m6A modification-mediated upregulation of ETS2 translation drives arsenic-induced spermatogonial senescence.
Zhang XY, Zhang YH, Liang NN, Xu SS, Li QS, Song YP, Zhang WW, Wang B, Wang H, Huang YC, Xu DX, et al.
Free radical biology & medicine (2025) : . 202 003 MeRIP; tested species: mouse

ALKBH5 deficiency suppresses hepatocarcinogenesis in mice via m6A-dependent STAT1 restoration.
Wang KT, Yang S, Zhao ZH, Rui CH, Shen SY, Cao D, Guo LN, Tang SH, Chen L, Wang HY, Qiu XY, et al.
Acta pharmacologica Sinica (2025) : . 202 003 MeRIP; tested species: human

METTL3-dependent epigenetic regulation of ULK2 autophagy in hypertrophic scarring.
Li X, Chen WW, Wu JJ, Yuan ZD, Yuan FL, Chen J
International journal of biological macromolecules (2025) 315Pt 1: 144507. 202 003 MeRIP; tested species: rabbit

Targeting YTHDF2 with pH-responsive siRNA nanoparticles suppresses MYC m6A modification and restores antitumor immunity in hepatocellular carcinoma.
Guo Z, Huang Q, Cui Z, Yang C, Yang L
Journal of nanobiotechnology (2025) 231: 469. 202 003 MeRIP; tested species: mouse

m6A modification profiles of the CHO cells with differential recombinant protein expression using MeRIP-seq/RNA-seq.
Wang W, Wang HT, Guo Y, Zhao Q, Lu JT, Cui ZM, Zhang X, Qiu LL, Wang XY, Wang TY, Jia YL, et al.
International journal of biological macromolecules (2025) 310Pt 4: 143429. 202 003 MeRIP

NERD-dependent m6A modification of the nascent FLC transcript regulates flowering time in Arabidopsis.
Shao Y, Ma J, Zhang S, Xu Y, Yu H
Nature plants (2025) 113: 468-482. 202 003 MeRIP

Unraveling the protective role of m6A methylation in SLC22A3 expression for breast Cancer intervention.
Xiao Y, Cao C, Zhang Y, Zhao C, Liu Y
Biochimica et biophysica acta. Molecular basis of disease (2025) 18717: 167962. 202 003 MeRIP; tested species: mouse

Comprehensive Analysis of Differences in N6-Methyladenosine RNA Methylation Groups in CVB3-Induced Viral Myocarditis and Identification of the Anti-Apoptotic Role of RBM15B.
Hu Y, Lin J, Yi L, Cheng S, You G, Chang H, Liu H, Yang Z, Chen S
Journal of inflammation research (2025) 18: 7933-7949. 202 003 MeRIP; tested species: mouse

USP10-stabilized IGF2BP3 promotes tumor growth via m6A-modified SKP2 mRNA in non-small-cell lung cancer.
Wang C, Hou X, Guan Q, Zhou H, Luo Y, Jin W, Bai F, Liu L, Wang J, Xie L, Li F, et al.
International journal of biological macromolecules (2025) 329Pt 1: 147753. 202 003 MeRIP; tested species: human

Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1.
Si W, Wang CL, Zeng LH, Zhao QY, Xie YT, Yang Y, Diao HT, Song JL, Wu H, Zhang F, Wang Z, et al.
Acta pharmacologica Sinica (2025) : . 202 003 MeRIP; tested species: mouse

N6-Methyladenosine Modification Regulates Prunus Necrotic Ringspot Virus Infection in Cucumis sativus.
Dong Z, Liu N, Zhang Z, Wang H, Li S, Zhan B
Journal of agricultural and food chemistry (2025) : . 202 003 MeRIP

Chinese sacbrood virus mediates m6A modification to target and suppress the expression of hemolymph maintenance gene AF9, exacerbating bee infections.
Bai H, Ma Y, Qiu H, Qi Y, Huang Y, Guo Y, Sun L, Li M, Fei D, Ma M, Liu Y, et al.
Journal of virology (2025) 993: e0211724. 202 003 MeRIP

KRAS mutants confer platinum resistance by regulating ALKBH5 posttranslational modifications in lung cancer.
Yu F, Zheng S, Yu C, Gao S, Shen Z, Nar R, Liu Z, Huang S, Wu L, Gu T, Qian Z, et al.
The Journal of clinical investigation (2025) 1356: . 202 003 MeRIP; tested species: human

TRIM21-mediated METTL3 degradation promotes PDAC ferroptosis and enhances the efficacy of Anti-PD-1 immunotherapy.
Mao W, Jiang Q, Feng Y, Peng C, Peng H, Li X, Jiao L, Zhang L, Ma L, Sun T
Cell death & disease (2025) 161: 240. 202 003 MeRIP; tested species: human

Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea.
Lan J, Wang Y, Liu C, Chen H, Chen Q
BMC pulmonary medicine (2025) 251: 158. 202 003 MeRIP; tested species: mouse

Integrated m6A RNA methylation and transcriptomic analysis of Apostichopus japonicus under combined high-temperature and hypoxia stress.
Wang Q, Zhang S, He X, Li S, Xu X, Feng Y, Yang J, Sun G
BMC genomics (2025) 261: 363. 202 003 MeRIP

FTO controls CD8+ T cell survival and effector response by modulating m6A methylation of Fas.
Sun L, Zhang T, Ge Y, Yao Z, Su Y, Wang Q, Chen Y, He B, Ding R, Zhang C, Lan L, et al.
Cell death & disease (2025) 161: 301. 202 003 MeRIP; tested species: mouse

Nuclear accumulation of YTHDF1 regulates mRNA splicing in the DNA damage response.
Hou J, Gao Y, Han B, Yan S, Wei S, Gao X
Science advances (2025) 1116: eado7660. 202 003 MeRIP; tested species: human

Curdione inhibits the proliferation of human uterine leiomyomas by targeting YTHDF1.
Yang X, Zuo J, Qiu T, Ren H, Qian R, Luo W, Chen Z, Li D
Phytomedicine : international journal of phytotherapy and phytopharmacology (2025) 144: 156938. 202 003 MeRIP; tested species: human

The role of IGF2BP2 in macrophage-mediated NLRP3 inflammasome activation in the pathogenesis of dry AMD.
Zhao Y, Zhang Y, Li J, Zhang Y, Qu Y
Biology direct (2025) 201: 57. 202 003 MeRIP; tested species: mouse

Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1.
Liu Z, Gu S, Peng Z, Wang Y, Li H, Zeng X, Wang H, Lv P, Wu Y, Zhou Y, Zhang Y, et al.
Cell death & disease (2025) 161: 345. 202 003 MeRIP; tested species: human

Comprehensive comparison of the third-generation sequencing tools for bacterial 6mA profiling.
Lu B, Guo Z, Liu X, Ni Y, Xu L, Huang J, Li T, Feng T, Li R, Deng X
Nature communications (2025) 161: 3982. 202 003 MeRIP; tested species: e. coli

BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner.
Liu X, Zeng S, Meng J, Zhou Q, Cao F, Chu B, Wu C, Wang Y, Feng H, Bi X, Chen X, et al.
Theranostics (2025) 1511: 5481-5498. 202 003 MeRIP; tested species: human

Transcriptome-wide study of mRNAs modified by m6A RNA methylation in the testis development of dairy goats.
Ren X, Qu Y, Shari A, Li G
Animal biotechnology (2025) 361: 2496641. 202 003 MeRIP

The motor neuron m6A repertoire governs neuronal homeostasis and FTO inhibition mitigates ALS symptom manifestation.
Yen YP, Lung TH, Liau ES, Wu CC, Huang GL, Hsu FY, Chang M, Yang ZD, Huang CY, Zheng Z, Zhao W, et al.
Nature communications (2025) 161: 4063. 202 003 MeRIP; tested species: mouse

The cardiac METTL3/m6A pathway regulates the systemic response to Western diet.
Rabolli C, Longenecker JZ, Naarmann-de Vries IS, Serrano J, Petrosino JM, Kyriazis GA, Dieterich C, Accornero F
JCI insight (2025) 1011: . 202 003 MeRIP; tested species: mouse

H3K18 lactylation-mediated Ythdf2 activation restrains mouse female germline stem cell proliferation via promoting Ets1 mRNA degradation.
Wu Y, Xu B, Peng Y, Lin S, Du W, Liu R, Zhang S, Wu J, Zou K, Zhao X
Clinical epigenetics (2025) 171: 84. 202 003 MeRIP; tested species: mouse

Rewired m6A of promoter antisense RNAs in Alzheimer's disease regulates neuronal genes in 3D nucleome.
Hu B, Shi Y, Xiong F, Chen YT, Zhu X, Carrillo E, Wen X, Drolet N, Rajpurohit CS, Xu X, Lee DF, et al.
Nature communications (2025) 161: 5251. 202 003 MeRIP; tested species: human

A novel mechanism of radiation-induced lung injury: METTL3 mediates fibrogenesis through N6-methyladenosine modification of YY1.
Xu W, Yi J, Wei X, Wang M, Zhao M, Zhao M, Wang X, Shen Y, Wang Z, Jin S
Journal of translational medicine (2025) 231: 629. 202 003 MeRIP; tested species: human,mouse

YTHDF3 regulates IL32 mRNA stability to promote osteogenic differentiation of bone mesenchymal stem cells in ankylosing spondylitis.
Zhou B, Feng X, Han C, Wu Y, Qiao J, Tong W, Xu W
Journal of translational medicine (2025) 231: 604. 202 003 MeRIP; tested species: human

CircSLC22A3 inhibits the invasion and metastasis of ESCC via the miR-19b-3p/TRAK2 axis and by reducing the stability of m6A-modified ACSBG1 mRNA.
Pan Y, Yang H, Zhang J, Zhang R, Liu Y, Bie J, Chen Q, Qiao Y, Liu K, Song G
BMC cancer (2025) 251: 971. 202 003 MeRIP; tested species: human

cIAP2-mediated IGF2BP2 ubiquitination and degradation regulate cardiomyocyte apoptosis via stabilizing m6A-modified BAX mRNA in myocardial infarction.
Wang C, Liu J, Hou X, Guan Q, Zhou H, Luo Y, Jin W, Bai F, Liu L, Wang J, Xie L, et al.
Cell biology and toxicology (2025) 411: 92. 202 003 MeRIP; tested species: human

METTL14-mediated miR-122-5p maturation stimulated tumor progression by targeting KAT2A in hepatocellular carcinoma.
Fan X, Qiao W, Guo X, Wang J, Zhao L
Scientific reports (2025) 151: 17884. 202 003 MeRIP; tested species: human

Development of a brain-penetrant G9a methylase inhibitor to target Alzheimer's disease-associated proteopathology.
Xie L, Sheehy RN, Muneer A, Xiong Y, Wrobel JA, Zhang F, Park KS, Velez J, Liu J, Luo YJ, Asrican B, et al.
Nature communications (2025) 161: 4222. 202 003 MeRIP; tested species: mouse

m6A modification is incorporated into bacterial mRNA without specific functional benefit.
Szydlo K, Santos L, Christian TW, Maharjan S, Dorsey A, Masuda I, Jia J, Wu Y, Tang W, Hou YM, Ignatova Z, et al.
Nucleic acids research (2025) 5310: . 202 003 MeRIP; tested species: e. coli

FSP1 Acts in Parallel with GPX4 to Inhibit Ferroptosis in Chronic Obstructive Pulmonary Disease.
Yang Y, Shen W, Zhang Z, Dai Y, Zhang Z, Liu T, Yu J, Huang S, Ding Y, You R, Wang Z, et al.
American journal of respiratory cell and molecular biology (2025) 725: 551-562. 202 003 MeRIP; tested species: human

METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation.
Zhao C, Hu B, Wang Z, Zhang Z, Luo W, Li H, Zhang X
Poultry science (2025) 1047: 105216. 202 003 MeRIP; tested species: chicken

Cardiovascular Mettl3 Deficiency Causes Congenital Cardiac Defects and Postnatal Lethality in Mice.
Feng Q, Qi L, Huang J, Dong Z, Yu F, Zhang J, Zhan J, Zhang H, Wang W, Zhou Y, Yang Z, et al.
International journal of biological sciences (2025) 216: 2430-2445. 202 003 MeRIP; tested species: mouse

K88 acetylation of FTO increases its RNA m6A demethylation and promotes tumorigenesis.
Li J, Zhang X, Zhao SY, Ran L, Zhang M, Xie S, Zhu H, Yan GR
Oncogene (2025) 4433: 3014-3024. 202 003 MeRIP; tested species: human

The significance of m6A-circFOXK2 in CD4+T cells from patients with rheumatoid arthritis and circFOXK2 correlates with Th17 % and autophagy.
Luo Q, Wu Z, Xiao Q, Lan M, Wang S, Fu P, Fu B, Huang Z, Li J
Journal of translational autoimmunity (2025) 11: 100326. 202 003 MeRIP; tested species: human

The m6A reader SlYTH1 regulates flavor-related volatiles biosynthesis via affecting mRNA stability and translation in tomato fruit.
Gao Y, Bian H, Wang H, Wang J, Ye B, Zhang C, Xu M, Pan Y, Deng Z, Li Z, Chen K, et al.
Plant physiology (2025) 1983: . 202 003 MeRIP

N6-methyladenosine reader YTHDF1 mediates neuronal apoptosis induced by aluminum via m6A/Bcl-2 manner.
Song J, Ding X, Li M, Xin Y, Lu Y, Yang X, Lu X
Ecotoxicology and environmental safety (2025) 306: 119270. 202 003 MeRIP; tested species: rat

Single-base m6A epitranscriptomics reveals novel HIV-1 host interaction targets in primary CD4+ T cells.
Huang S, Zhao Y, Phillips S, Warrick JE, Kearse MG, He C, Wu L
Journal of virology (2025) : e0153625. 202 003 MeRIP; tested species: human

METTL3 Exacerbates Intimal Hyperplasia by Facilitating m6A-YTHDC1-Dependent SGK1 Gene Transcription.
Huang J, Feng Q, Dong Z, Li Z, Liu Y, Xu R, Liu Z, Ding Q, Yang X, Yu F, Jia Y, et al.
Arteriosclerosis, thrombosis, and vascular biology (2025) 459: e437-e453. 202 003 MeRIP; tested species: rat

Multi-omics analysis reveals the crosstalk of epigenetic regulatory networks in cutaneous squamous cell carcinoma progression.
Sun YZ, Zou DD, Li XJ, Wang XL, Feng JH, Liu JY, He K, He YT, Lai XX, Li X, Jiang X, et al.
Journal of translational medicine (2025) 231: 1281. 202 003 MeRIP; tested species: human

Mechanism of METTL14-mediated RAD21 mRNA epigenetic transcriptome modification in inhibiting thyroid cancer development.
Ge Y, Qin C, Xiao M
World journal of surgical oncology (2025) 231: 434. 202 003 MeRIP; tested species: human

M6A-ALKBH5-dependent RBMS3-AS3 down-regulation suppresses ferroptosis to promote lung adenocarcinoma progression through HNRNPDL/ZEB1/GPX4 axis.
Ge W, Wang Q, Wang H, Zhang W, Chen L, Li Z, Wu W
NPJ precision oncology (2025) 91: 356. 202 003 MeRIP; tested species: human

A comprehensive analysis of differential RNA m6A methylation modifications across the entire transcriptome in PTSD through high-throughput MeRIP sequencing.
Yang L, Lu J, Lu K, Hu M, Zhang G
Brain research bulletin (2025) 233: 111665. 202 003 MeRIP; tested species: human

FKBP9 enhances IGF2BP1-mediated m6A recognition to promote hepatocellular carcinoma progression.
Yang F, Si A, Chi C, Ma W, Gu Y, Pan Y, Zhu J, He Y, Tang X, Yu Q, Chen Y, et al.
JHEP reports : innovation in hepatology (2025) 712: 101584. 202 003 MeRIP; tested species: human

Synergistic function of RNA modifications in Arabidopsis and rice.
Ma A, Wang S, He X, Qu Y, Xie S, Gao J, Peng Y, Shen L, Pu W, He C
aBIOTECH (2025) 64: 803-815. 202 003 MeRIP

The ZFP36-FTO axis is a key regulator of macrophage activation and a druggable therapeutic target of sepsis.
Sarkar R, Wang L, Du J, Blackshear PJ, Li YC
iScience (2025) 2812: 114060. 202 003 MeRIP; tested species: mouse

Tumor-associated macrophage-derived exosomes modulate the immunotherapeutic sensitivity of SHH-medulloblastoma by targeting m6A-modified FOXD1.
Liu Y, Peng Y, Song C, Liu Z, Yang X, Bian S, Xiao X, Li H, Wang J, Sun Z, Liu X, et al.
Neuro-oncology (2025) : . 202 003 MeRIP; tested species: human

YTHDC1-Mediated m6A Modification of MAGI3 mRNA Regulates Proliferation and Differentiation of Myoblasts.
Chen Q, He S, Xue X, Zhang W, Li H, He X, Pu Y, Ma Y, Jiang L, Zhao Y, Zhao Q, et al.
Journal of agricultural and food chemistry (2025) : . 202 003 MeRIP; tested species: sheep

METTL3/RBM15 augments the stability of Kdm6b mRNA and promotes STAT1-mediated macrophage activation and atherosclerosis.
Huangfu N, Li F, Wang C, Jin S, Zheng X, Wang Y, Fang T, Shen J, Yu Y, Jian L, Qi D, et al.
Experimental & molecular medicine (2025) : . 202 003 MeRIP; tested species: mouse

RNA m6A-binding protein YTHDF2 regulates neoblast proliferation in planarian regeneration by targeting ASTACIN Signaling.
Zheng H, Wang D, Li L, Xu Q, Cheng M, Chen J, Zhu S, Lin D, Lin R, Xue W, Liu S, et al.
Journal of advanced research (2025) : . 202 003 MeRIP

USP5 promotes glycolysis of fibroblast-like synoviocytes by stabilizing the METTL14/m6A/GLUT1 axis in rheumatoid arthritis.
Li X, Ling M, Wen Z, Jiang C, Tan X
Cell death discovery (2025) 121: 32. 202 003 MeRIP; tested species: human

N6-Methyladenosine (m6A) Methylation-Mediated Transcriptional Regulation in Maize Root Response to Salt Stress.
Ta W, Zhuang Z, Bian J, Ren Z, Hao X, Zhang L, Peng Y
Plants (Basel, Switzerland) (2025) 151: . 202 003 MeRIP

m 6 A-mediated gluconeogenic enzyme PCK1 upregulation protects against hepatic ischemia-reperfusion injury.
Yu S, Liu X, Xu Y, Pan L, Zhang Y, Li Y, Dong S, Tu D, Sun Y, Zhang Y, Zhou Z, et al.
Hepatology (Baltimore, Md.) (2025) 811: 94-110. 202 003 MeRIP; tested species: mouse

The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint.
Flaherty JN, Sivasudhan E, Tegowski M, Xing Z, McGinnis MM, Hunter OV, Featherston KM, Sethia K, Tu BP, Meyer KD, Conrad NK, et al.
Cell reports (2025) 447: 115966. 202 003 MeRIP; tested species: human

Landscape and m6A post-transcriptional regulation of soybean proteome.
Yang Q, Hou ZY, Li L, Wang L, Li ST, Li Y, Zhang X, Huang H, Ke Y, Ma X, Wu Z, et al.
Cell genomics (2025) 59: 100926. 202 003 MeRIP

Heat shock protein 70 regulates m6A modification in response to heat shock in esophageal squamous cell carcinoma.
Du B, Wang J, Ma J, Wang P
Biochimica et biophysica acta. Molecular cell research (2025) 18728: 120027. 202 003 MeRIP; tested species: human

Evolutionary analysis and immune-induced expression and m6A modification of RIPK1 and RIPK2 in the miiuy croaker.
Xing Q, Geng S, Lv X, Sun Y, Xu T
Fish & shellfish immunology (2025) 167: 110903. 202 003 MeRIP

ECT10 is an m6A reader that negatively regulates the drought stress response in Arabidopsis by modulating mRNA stability.
Han R, Nguyen TKH, Yang Z, Kang H
The Plant journal : for cell and molecular biology (2025) 1245: e70637. 202 003 MeRIP

FTO Modulates m6A RNA Methylation of STC1 to Regulate Inflammation and Oxidative Stress in Diabetic Nephropathy.
Pan S, Li D, Cao F, Zhou S, Liu F, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2025) 3923: e71299. 202 003 MeRIP; tested species: human

Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation.
Xiao M, Wang X, Xiao E, Ming Q
Functional & integrative genomics (2025) 251: 17. 202 003 MeRIP; tested species: mouse

CRTC2 Forms Co-Condensates with YTHDF2 That Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
Wang M, Zou F, Wang S, Yang Y, Xia C, Chen L, Liu B, Li L, Li MJ, Li H, Song W, et al.
Cancer research (2025) 8511: 2046-2066. 202 003 MeRIP; tested species: human

P4HA2 interacted with ATAD3A to modulate PINK1/parkin-dependent mitophagy and 125I brachytherapy sensitization in esophageal carcinoma.
Yao X, Feng C, Huang X, Wu S, Lu S, Gao Y, Sun T, Bai X, Li C, Jia K, Han X, et al.
Cell death & disease (2025) 161: 685. 202 003 MeRIP; tested species: human

METTL5-mediated m6A modification of UBE3C promotes osteosarcoma progression by suppressing ferroptosis via inducing AHNAK ubiquitination.
Chen N, Zhang Z, Shen F, Lu D
Journal of molecular histology (2025) 564: 235. 202 003 MeRIP; tested species: human

HnRNPA2B1 promotes cardiac ferroptosis via m6A-dependent stabilization of PFN2 mRNA in myocardial ischemia-reperfusion injury.
Shi S, Chen Q, Yang Y, Li Z, Zheng R, Zhang R, Liu Z, Cheng Y
Free radical biology & medicine (2025) 232: 231-243. 202 003 MeRIP; tested species: human

Silencing YTHDF2 Induces Apoptosis of Neuroblastoma Cells In a Cell Line-Dependent Manner via Regulating the Expression of DLK1.
Hua Z, Gong B, Li Z
Molecular neurobiology (2025) 627: 8121-8134. 202 003 MeRIP; tested species: human

ZNF384 and m6A methylation promote the progression of hepatocellular carcinoma by regulating the interaction between LINC00342 and DAPK1.
Kong S, Li J, Pan X, Zhao C, Li Y
Cellular signalling (2025) 129: 111666. 202 003 MeRIP; tested species: human

Heat stress enhances the expression of METTL3 to mediate N6-methyladenosine modification of SOS2 and NLRP3 inflammasome activation in boar Sertoli cells.
Zhang X, Tang Y, Wang J, Yang M, Jiang J, Xue H, Wang Y, Zhang J, Wang X
Journal of hazardous materials (2025) 488: 137432. 202 003 MeRIP; tested species: pig

Feedback regulation of m6A modification creates local auxin maxima essential for rice microsporogenesis.
Cheng P, Zhao H, Zhang S, Zong Z, Li C, Ming L, Xie W, Yu H
Developmental cell (2025) 6010: 1454-1466.e4. 202 003 MeRIP

Redox modification of m6A demethylase SlALKBH2 in tomato regulates fruit ripening.
Zhou L, Gao G, Tang R, Liu J, Wang Y, Liang Z, Tian S, Qin G
Nature plants (2025) 112: 218-233. 202 003 MeRIP

Nanopore RNA direct sequencing identifies that m6A modification is essential for sorbitol-controlled resistance to Alternaria alternata in apple.
Song Z, Yang Q, Dong B, Wang S, Xue J, Liu N, Zhou X, Li N, Dandekar AM, Cheng L, Meng D, et al.
Developmental cell (2025) 6010: 1439-1453.e5. 202 003 MeRIP

ADAP-METTL3 modulates the inflammatory responses of macrophages via m6A modification of Spry1.
Dong A, Zhang P, Yang F, Wang Y, Liu H
Cell death & disease (2025) 161: 708. 202 003 MeRIP; tested species: mouse

Arginine methylation-dependent METTL14-SMN interaction regulates RNA m6A homeostasis.
Zhang Y, Shen L, Ren L, Wei J, Pham HQH, Tao X, Guo J, Wang Z, Shen B, Su R, He C, et al.
EMBO reports (2025) : . 202 003 MeRIP; tested species: human

METTL14 alleviates sepsis-induced acute kidney injury by targeting Hmox1-mediated ferroptosis through m6A modification.
Yang C, Zhao L, Di J, Zhou X
Journal of molecular histology (2025) 564: 240. 202 003 MeRIP; tested species: human

Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity.
Zhang S, Cui Z, Zhang D, Zhang D, Jin K, Li Z, Li B, Cong B, Liu J, Wang L, Wen M, et al.
Cell metabolism (2025) 372: 413-428.e7. 202 003 MeRIP; tested species: mouse

ALKBH5-IGF2BP2 axis mediates prostate cancer progression and docetaxel resistance via m6A-stabilized CLSPN RNA.
Chen Y, Li Y, Liang Z, Yang Z, Ren H, Wei W, Niu Y, Shang Z
iScience (2025) 2810: 113520. 202 003 MeRIP; tested species: human

VIRMA-mediated SHQ1 m6A modification enhances liver regeneration through an HNRNPA2B1-dependent mechanism.
Chen H, Wang H, Huang J, Qiu G, Zhang Z, Xu L, Ma X, Wang Z, Chen X, Zeng Y
Acta pharmaceutica Sinica. B (2025) 1510: 5212-5230. 202 003 MeRIP; tested species: mouse

Intranuclear paraspeckle-circular RNA TACC3 assembly forms RNA-DNA hybrids to facilitate MASH-related hepatocellular carcinoma growth in an m6A-dependent manner.
Fu J, Wei Y, Yang Y, Yang X, Ouyang T, Wang X, Chen S, Liu Z, Su Y, Fu J, Yu M, et al.
Cancer communications (London, England) (2025) : . 202 003 MeRIP; tested species: human

Atorvastatin Alleviates Sepsis-Induced Cardiomyopathy by Targeting the METTL3/IGF2BP1/CXCL2 Pathway.
Zhang L, Yin Y, Zheng L, Wang Y, Zhao J, Mu F, Jin F, Gong R, Wang J
Journal of inflammation research (2025) 18: 14609-14628. 202 003 MeRIP; tested species: mouse

mRNA m6A regulates gene expression via H3K4me3 shift in 5' UTR.
Yang Y, Huang Y, Wang T, Li S, Jiang J, Chen S, Chen F, Wang L
Genome biology (2025) 261: 54. 202 003 MeRIP

METTL3-mediated m6A modification promotes ferroptosis in adenomyosis through GPX4 in a YTHDF1-dependent manner.
Tang Y, Li Z, Zhao X, Niu X, Ning S, Liu L, Liu Z, Zhang J, Zhao Q, Han L
Reproduction (Cambridge, England) (2025) 1704: . 202 003 MeRIP; tested species: human

Zinc nanoparticles from oral supplements accumulate in renal tumours and stimulate antitumour immune responses.
Zeng X, Wang Z, Zhao A, Wu Y, Wang Z, Wu A, Wang Q, Xia X, Chen X, Zhao W, Li B, et al.
Nature materials (2025) 242: 287-296. 202 003 MeRIP; tested species: human

N6-methyladenosine improves porcine longissimus dorsi muscle quality by regulating myofiber differentiation.
Yin C, Yang S, Huang Y, Zhou Z, Huang J, Yang B, Huang L
BMC genomics (2025) 261: 850. 202 003 MeRIP; tested species: pig

Methyltransferase-like 3-catalysed N6-methyladenosine methylation facilitates the contribution of vascular smooth muscle cells to atherosclerosis.
Dong Z, Jin Y, Shen Y, Huang J, Tan J, Feng Q, Gong Z, Zhu S, Chen H, Yu F, Li W, et al.
Cardiovascular research (2025) 1214: 568-584. 202 003 MeRIP; tested species: mouse

Dam-dependent epigenetic memory regulates prophage reintegration in Salmonella.
Yang J, Son Y, Park J, Park W
Nucleic acids research (2025) 5318: . 202 003 MeRIP

Integrative epitranscriptomic and transcriptomic characterization in human colorectal cancer.
Gong T, Rai SK, Zhu Y, Wang Y, Chen Y, Ma L, Wei X, Ling Z, Pandey A, Qin Y, Huo M, et al.
Journal of advanced research (2025) : . 202 003 MeRIP; tested species: human

Integrated multi-omics analysis identifies potential therapeutic targets for Alzheimer's disease.
Li H, Kang J, Liang Z, Wang X, Zhu L, Tang H, Peng W
Neural regeneration research (2025) : . 202 003 MeRIP; tested species: mouse

IGF2BP1-Mediates m6A Modification of KLF4 and Upregulates ADRM1 to Affect EndMT in Diabetic Atherosclerosis.
Zhang Z, Guo Q, Zhao Z, Nie M, Shi Q, Li E, Liu K, Yu H, Rao L, Li M
Acta Cardiologica Sinica (2025) 415: 598-611. 202 003 MeRIP; tested species: human

METTL3-m6A-mediated TGF-β signaling promotes Fuchs endothelial corneal dystrophy via regulating corneal endothelial-to-mesenchymal transition.
Qiu J, Zhang X, Shi Q, Yang Y, Zhou R, Xiang J, Gu J, Xu J, Hong J, Shan K
Cell death discovery (2025) 111: 104. 202 003 MeRIP; tested species: human

Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia.
Sun T, Yu H, Zhang D, Zhang D, Li D, Fu J
Redox biology (2025) 82: 103586. 202 003 MeRIP; tested species: human

Comprehensive characterization of lncRNA N6-methyladenosine modification dynamics throughout bovine skeletal muscle development.
Mao C, You W, Yang Y, Cheng H, Hu X, Lan X, Song E
Journal of animal science and biotechnology (2025) 161: 36. 202 003 MeRIP; tested species: cow

METTL14-mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.
Liu Z, Sun T, Zhang Z, Piao C, Kong C, Zhang X
Clinical and translational medicine (2025) 152: e70232. 202 003 MeRIP; tested species: human

ALKBH3-Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation.
Tu L, Gu S, Xu R, Yang E, Huang X, Liang H, Luo S, Li H, Zhao Y, Zan T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025) : e2417067. 202 003 MeRIP; tested species: human

WTAP regulates Mitochondrial damage and Lipid oxidation in HCC by NOA1 mediated m6A modification.
Liu S, Shang M, Gong J, Sun H, Hu B
Journal of Cancer (2025) 161: 315-330. 202 003 MeRIP; tested species: human

Comparative analysis of improved m6A sequencing based on antibody optimization for low-input samples.
Lu J, Xia W, Li J, Zhang L, Qian C, Li H, Huang B
Scientific reports (2025) 151: 1058. 202 003 MeRIP; tested species: human,mouse

Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV.
Miao Q, Jiang J, Huang S, Gao J, Liu Q, Zheng R, Kang Y, Guo C, He J, Xie J
BMC genomics (2025) 261: 22. 202 003 MeRIP

ALKBH5 suppresses gastric cancer tumorigenesis and metastasis by inhibiting the translation of uncapped WRAP53 RNA isoforms in an m6A-dependent manner.
Zheng Z, Lin F, Zhao B, Chen G, Wei C, Chen X, Nie R, Zhang R, Zhao Z, Zhou Z, Li Y, et al.
Molecular cancer (2025) 241: 19. 202 003 MeRIP; tested species: human

Methyltransferase-like 3 mediates m6A modification of heme oxygenase 1 mRNA to induce ferroptosis of renal tubular epithelial cells in acute kidney injury.
Lv L, Hu M, Li J, Guo R, He M, Zhou P, Lei Y, Chen M, Liu Z, Zhou S
Free radical biology & medicine (2025) : . 202 003 MeRIP; tested species: mouse

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation-Associated Microglial Response.
Zhang N, Lin R, Gao W, Xu H, Li Y, Huang X, Wang Y, Jing X, Meng W, Xie Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025) : e2405263. 202 003 MeRIP; tested species: mouse

Epitranscriptome profiles reveal participation of the RNA methyltransferase gene OsMTA1 in rice seed germination and salt stress response.
Li Y, Yin M, Wang J, Zhao X, Xu J, Wang W, Fu B
BMC plant biology (2025) 251: 115. 202 003 MeRIP

Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Peng C, Wang M, Zheng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety (2025) 291: 117913. 202 003 MeRIP; tested species: human

A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner.
Ding XY, Zhang HY, Chen JH, Yang MJ, Huang ZX, Lei YH, Sun QK, Bai JB, Lin DC, Lan JF, Ren LL, et al.
Molecular medicine (Cambridge, Mass.) (2025) 311: 78. 202 003 MeRIP; tested species: human

DRAIC mediates hnRNPA2B1 stability and m6A-modified IGF1R instability to inhibit tumor progression.
Wen Y, Yang X, Li Y, Zhao X, Ding A, Song D, Duan L, Cheng S, Zhu X, Peng B, Chang X, et al.
Oncogene (2024) : . 202 003 MeRIP; tested species: mouse

Increased m6A modification of BDNF mRNA via FTO promotes neuronal apoptosis following aluminum-induced oxidative stress.
Song J, Hao J, Lu Y, Ding X, Li M, Xin Y
Environmental pollution (Barking, Essex : 1987) (2024) 349: 123848. 202 003 MeRIP; tested species: rat

Hsa_circ_0007590/PTBP1 complex reprograms glucose metabolism by reducing the stability of m6A-modified PTEN mRNA in pancreatic ductal adenocarcinoma.
Zheng D, Chen W, Peng J, Huang X, Zhang S, Zhuang Y
Cancer gene therapy (2024) : . 202 003 MeRIP; tested species: human

Identification of key differentially methylated genes in regulating muscle development and intramuscular fat deposition in chickens.
Yu B, Cai Z, Liu J, Zhang T, Feng X, Wang C, Li J, Gu Y, Zhang J
International journal of biological macromolecules (2024) 264Pt 2: 130737. 202 003 MeRIP; tested species: chicken

Identification of AtALKBH1A and AtALKBH1D as DNA N6-adenine demethylases in Arabidopsis thaliana.
Li D, Du J, Gao M, He C
Plant science : an international journal of experimental plant biology (2024) 342: 112055. 202 003 MeRIP

Transcriptome-Wide N6-Methyladenosine Alternations in Pulmonary Arteries of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats and Novel Therapeutic Targets.
Feng Y, Yu Z, Tang M, Li J, Peng B, Juaiti M, Tang Y, Liang B, Ouyang M, Liu Q, Song J, et al.
Biomedicines (2024) 122: . 202 003 MeRIP; tested species: rat

METTL3 inhibitor STM2457 impairs tumor progression and enhances sensitivity to anlotinib in OSCC.
Liu L, Zhao T, Zheng S, Tang D, Han H, Yang C, Zheng X, Wang J, Ma J, Wei W, Wang Z, et al.
Oral diseases (2024) : . 202 003 MeRIP; tested species: human

Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program.
Gao L, Lee H, Goodman JH, Ding L
Cell (2024) 18711: 2801-2816.e17. 202 003 MeRIP; tested species: mouse

METTL3-mediated m6A modification of NORAD inhibits the ferroptosis of vascular smooth muscle cells to attenuate the aortic dissection progression in an YTHDF2-dependent manner.
Liao M, Zou S, Wu J, Bai J, Liu Y, Zhi K, Qu L
Molecular and cellular biochemistry (2024) : . 202 003 MeRIP; tested species: human,mouse

Characterizing Post-transcriptional Modifications of circRNAs to Investigate Biogenesis and Translation.
Di Timoteo G, Dattilo D, Bozzoni I
Methods in molecular biology (Clifton, N.J.) (2024) 2765: 263-296. 202 003 MeRIP

The m6A reader IGF2BP1 attenuates the stability of RPL36 and cell proliferation to mediate benzene hematotoxicity by recognizing m6A modification.
Wang J, Guo X, Chen Y, Zhang W, Ren J, Gao A
Toxicology (2024) 503: 153758. 202 003 MeRIP; tested species: human,mouse

N6-methyladenosine analysis unveils key mechanisms underlying long-term salt stress tolerance in switchgrass (Panicum virgatum).
Liu H, Lin M, Wang H, Li X, Zhou D, Bi X, Zhang Y
Plant science : an international journal of experimental plant biology (2024) 342: 112023. 202 003 MeRIP

Nicotine-derived NNK promotes CRC progression through activating TMUB1/AKT pathway in METTL14/YTHDF2-mediated m6A manner.
Jiang M, Han J, Ma Q, Chen X, Xu R, Wang Q, Zheng J, Wang W, Song J, Huang Y, Chen Y, et al.
Journal of hazardous materials (2024) 467: 133692. 202 003 MeRIP; tested species: human

Drought-induced circular RNAs in maize roots: separating signal from noise.
Xu J, Wang Q, Tang X, Feng X, Zhang X, Liu T, Wu F, Wang Q, Feng X, Tang Q, Lisch D, et al.
Plant physiology (2024) : . 202 003 MeRIP

m6A modification of lncRNA PHKA1-AS1 enhances Actinin Alpha 4 stability and promotes non-small cell lung cancer metastasis.
Guo QR, Zhang GB, Zhou WM, Lu Y, Chen XZ, Deng ZF, Li JS, Bi H, Wu MS, Xie MR, Yan YY, et al.
MedComm (2024) 56: e547. 202 003 MeRIP; tested species: human

N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension.
Kang K, Xiang J, Zhang X, Xie Y, Zhou M, Zeng L, Zhuang J, Kuang J, Lin Y, Hu B, Xiong Q, et al.
Cellular & molecular biology letters (2024) 291: 69. 202 003 MeRIP; tested species: human,mouse

The m6A methyltransferase RBM15 affects tumor cell stemness and progression of cervical cancer by regulating the stability of lncRNA HEIH.
Quan Y, Zhou M, Li J, Yang Y, Guo J, Tang T, Liu P
Experimental cell research (2024) 4362: 113924. 202 003 MeRIP; tested species: human

RNA demethylase FTO participates in malignant progression of gastric cancer by regulating SP1-AURKB-ATM pathway.
Zeng X, Lu Y, Zeng T, Liu W, Huang W, Yu T, Tang X, Huang P, Li B, Wei H
Communications biology (2024) 71: 800. 202 003 MeRIP; tested species: human

Unveiling blood pressure-associated genes in aortic cells through integrative analysis of GWAS and RNA modification-associated variants.
Zhang H, Chen Y, Xu P, Liu D, Wu N, Wang L, Mo X
Chronic diseases and translational medicine (2024) 102: 118-129. 202 003 MeRIP; tested species: human

N6-methyladenosine-driven miR-143/145-KLF4 circuit orchestrates the phenotypic switch of pulmonary artery smooth muscle cells.
Kang K, Sun C, Li H, Liu X, Deng J, Chen S, Zeng L, Chen J, Liu X, Kuang J, Xiang J, et al.
Cellular and molecular life sciences : CMLS (2024) 811: 256. 202 003 MeRIP; tested species: human

Alteration of RNA m6A methylation mediates aberrant RNA binding protein expression and alternative splicing in condyloma acuminatum.
Liu X, Xie B, Wang S, Wu Y, Zhang Y, Ruan L
PeerJ (2024) 12: e17376. 202 003 MeRIP; tested species: human

Morphine-Driven m6A Epitranscriptomic Neuroadaptations in Primary Cortical Cultures.
Dabrowski KR, Daws SE
Molecular neurobiology (2024) : . 202 003 MeRIP; tested species: rat

FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC.
Li R, Yan X, Xiao C, Wang T, Li X, Hu Z, Liang J, Zhang J, Cai J, Sui X, Liu Q, et al.
Nature communications (2024) 151: 4760. 202 003 MeRIP; tested species: human,mouse

BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation.
Zhang P, Zhang W, Wang X, Li L, Lin Y, Wu N, Mao R, Lin J, Kang M, Ding C
Cancer letters (2024) 591: 216874. 202 003 MeRIP; tested species: human

The m6A reader HNRNPC promotes glioma progression by enhancing the stability of IRAK1 mRNA through the MAPK pathway.
Chen JJ, Lu TZ, Wang T, Yan WH, Zhong FY, Qu XH, Gong XC, Li JG, Tou FF, Jiang LP, Han XJ, et al.
Cell death & disease (2024) 156: 390. 202 003 MeRIP; tested species: mouse

20(R)-Panaxatriol enhances METTL3-mediated m6A modification of STUB1 to inhibit autophagy and exert antitumor effects in Triple-Negative Breast Cancer cells.
Li Y, Luo B, Lin X, Bai D, Li L, Gao D, Li X, Zhong X, Wei Y, Yang L, Zhu X, et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology (2024) 130: 155537. 202 003 MeRIP; tested species: human

YTHDF1 is pivotal for maintenance of cardiac homeostasis.
Golubeva VA, Das AS, Rabolli CP, Dorn LE, van Berlo JH, Accornero F
Journal of molecular and cellular cardiology (2024) 193: 25-35. 202 003 MeRIP; tested species: mouse

Antiretroviral Therapy Suppresses RNA N6-Methyladenosine Modification in Peripheral Blood Mononuclear Cells from HIV-1-Infected Individuals.
Mishra T, Phillips S, Maldonado C, Stapleton JT, Wu L
AIDS research and human retroviruses (2024) : . 202 003 MeRIP; tested species: human

FTO-mediated regulation of m6A methylation is closely related to apoptosis induced by repeated UV irradiation.
Lin Y, Sun Y, Hou W, Chen X, Zhou F, Xu Q, Zheng Y
Journal of dermatological science (2024) : . 202 003 MeRIP; tested species: human

m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure.
Ouyang KW, Wang TT, Wang H, Luo YX, Hu YF, Zheng XM, Ling Q, Wang KW, Xiong YW, Zhang J, Chang W, et al.
The Science of the total environment (2024) 931: 172938. 202 003 MeRIP; tested species: mouse

N6-methyladenosine mRNA methylation positively regulated the response of poplar to salt stress.
Zhao Y, Han KJ, Tian YT, Jia KH, El-Kassaby YA, Wu Y, Liu J, Si HY, Sun YH, Li Y
Plant, cell & environment (2024) 475: 1797-1812. 202 003 MeRIP

Genome-wide screening of m6A profiling of cutaneous wound healing in diabetic mice.
Shen J, Chen H, Dai J
Molecular biology reports (2024) 511: 175. 202 003 MeRIP; tested species: mouse

RNA N6-Methyladenosine Affects Copper-Induced Oxidative Stress Response in Arabidopsis thaliana.
Sharma B, Govindan G, Li Y, Sunkar R, Gregory BD
Non-coding RNA (2024) 101: . 202 003 MeRIP

LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling.
Luo F, Zhang M, Sun B, Xu C, Yang Y, Zhang Y, Li S, Chen G, Chen C, Li Y, Feng H, et al.
Molecular cancer (2024) 231: 60. 202 003 MeRIP; tested species: human

Foot-and-mouth disease virus VP1 degrades YTHDF2 through autophagy to regulate IRF3 activity for viral replication.
Liu H, Xue Q, Yang F, Cao W, Liu P, Liu X, Zhu Z, Zheng H
Autophagy (2024) : 1-19. 202 003 MeRIP; tested species: mouse

WTAP-induced N6-methyladenosine of PD-L1 blocked T-cell-mediated antitumor activity under hypoxia in colorectal cancer.
Liu QZ, Zhang N, Chen JY, Zhou MJ, Zhou DH, Chen Z, Huang ZX, Xie YX, Qiao GL, Tu XH
Cancer science (2024) : . 202 003 MeRIP; tested species: human

PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.
Zhang Y, Song Z, Wu R, Kong X, Zhang H, Li S, Gong X, Gong S, Cheng J, Yuan F, Wu H, et al.
Cell reports (2024) 433: 113930. 202 003 MeRIP; tested species: mouse

ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m6A-dependent manner.
Wang H, Zhao S, Liu H, Liu Y, Zhang Z, Zhou Z, Wang P, Qi S, Xie J
International journal of biological sciences (2024) 205: 1729-1743. 202 003 MeRIP; tested species: human

Hypoxia-induced ALKBH5 aggravates synovial aggression and inflammation in rheumatoid arthritis by regulating the m6A modification of CH25H.
Fan D, Geng Q, Wang B, Wang X, Xia Y, Yang L, Zhang Q, Deng T, Xu Y, Zhao H, Liu B, et al.
Clinical immunology (Orlando, Fla.) (2024) 261: 109929. 202 003 MeRIP; tested species: rat

Ginger inhibits the invasion of ovarian cancer cells SKOV3 through CLDN7, CLDN11 and CD274 m6A methylation modifications.
Zhang X, Zhang H, Zhu L, Xia L
BMC complementary medicine and therapies (2024) 241: 145. 202 003 MeRIP; tested species: human

Programmable RNA N6 -methyladenosine editing with CRISPR/dCas13a in plants.
Shi C, Zou W, Liu X, Zhang H, Li X, Fu G, Fei Q, Qian Q, Shang L
Plant biotechnology journal (2024) : . 202 003 MeRIP

Dissecting the sequence and structural determinants guiding m6A deposition and evolution via inter- and intra-species hybrids.
Shachar R, Dierks D, Garcia-Campos MA, Uzonyi A, Toth U, Rossmanith W, Schwartz S
Genome biology (2024) 251: 48. 202 003 MeRIP; tested species: human,mouse

METTL14 enhances the m6A modification level of lncRNA MSTRG.292666.16 to promote the progression of non-small cell lung cancer.
Ji X, Wan X, Sun H, Deng Q, Meng S, Xie B, Zhou S
Cancer cell international (2024) 241: 61. 202 003 MeRIP; tested species: human

Transcriptome-wide N6-methyladenosine (m6A) methylation profiling of long non-coding RNAs in ovarian endometriosis.
Liu H, Liang J, Dai X, Peng Y, Xiong W, Zhang L, Li X, Li W, Liu K, Bi S, Wang X, et al.
Genomics (2024) 1162: 110803. 202 003 MeRIP; tested species: human

m6A modification mediates SLC3A2/SLC7A5 translation in 3-methylcholanthrene-induced uroepithelial transformation.
Liu B, Lv Y, Hu W, Huang Y, Ying X, Chen C, Zhang H, Ji W
Cell biology and toxicology (2024) 401: 5. 202 003 MeRIP; tested species: human

N6 -methyladenosine modification of RNA controls dopamine synthesis to influence labour division in ants.
Chen J, Guan Z, Sun L, Fan X, Wang D, Yu X, Lyu L, Qi G
Molecular ecology (2024) : e17322. 202 003 MeRIP

YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis.
Chen Z, Wang W, Hu S, Sun H, Chen C, Zhang Z, Sun X, Jia B, Hu J, Wang C, Liu Y, et al.
iScience (2024) 272: 108779. 202 003 MeRIP; tested species: human

METTL4 mediated-N6-methyladenosine promotes acute lung injury by activating ferroptosis in alveolar epithelial cells.
Sang A, Zhang J, Zhang M, Xu D, Xuan R, Wang S, Song X, Li X
Free radical biology & medicine (2024) 213: 90-101. 202 003 MeRIP; tested species: mouse

METTL3-mediated m6A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.
Feng ZW, Peng B, Wang SH, Zhao DC, Wang YB, Yang A, Zhan HW, Sheng XY, Xu LH, Ren XJ, Yang F, et al.
Cellular signalling (2024) 115: 111038. 202 003 MeRIP; tested species: mouse

Knockdown of fat mass and obesity alleviates the ferroptosis in Parkinson's disease through m6A-NRF2-dependent manner.
Pang P, Zhang S, Fan X, Zhang S
Cell biology international (2024) 484: 431-439. 202 003 MeRIP; tested species: human

Characterization of sexual maturity-associated N6-methyladenosine in boar testes.
Zhang P, Zhang F, Sui H, Yang X, Ji Y, Zheng S, Li W, Cheng K, Wang C, Jiao J, Zhang X, et al.
BMC genomics (2024) 251: 447. 202 003 MeRIP; tested species: pig

N6-methyladenosine-mediated feedback regulation of abscisic acid perception via phase-separated ECT8 condensates in Arabidopsis.
Wu X, Su T, Zhang S, Zhang Y, Wong CE, Ma J, Shao Y, Hua C, Shen L, Yu H
Nature plants (2024) 103: 469-482. 202 003 MeRIP

Manganese induces podocyte injury through regulating MTDH/ALKBH5/NLRP10 axis: Combined analysis at epidemiology and molecular biology levels.
Liang Q, Jing J, He H, Huang X, Liu J, Wang M, Qi Z, Zhang L, Huang Z, Yan Y, Liu S, et al.
Environment international (2024) 187: 108672. 202 003 MeRIP; tested species: mouse

MeRIP sequencing reveals the regulation of N6-methyladenosine in muscle development between hypertrophic and leaner broilers.
Wang Z, Ju X, Li K, Cai D, Zhou Z, Nie Q
Poultry science (2024) 1036: 103708. 202 003 MeRIP; tested species: chicken

Exploring the Roles of m6A-Modified circRNAs in Myasthenia Gravis Based on Multi-Omics Analysis.
Li S, Zhang Y, Liu G, Song N, Ruan Z, Guo R, Tang Y, Cao X, Huang X, Gao T, Hao S, et al.
Molecular neurobiology (2024) : . 202 003 MeRIP; tested species: human

Enhancing m6A modification of lncRNA through METTL3 and RBM15 to promote malignant progression in bladder cancer.
Huang Y, Lv Y, Yang B, Zhang S, Bixia Liu , Zhang C, Hu W, Jiang L, Chen C, Ji D, Xiong C, et al.
Heliyon (2024) 107: e28165. 202 003 MeRIP; tested species: human

OsALKBH9-mediated m6A demethylation regulates tapetal PCD and pollen exine accumulation in rice.
Tang J, Lei D, Yang J, Chen S, Wang X, Huang X, Zhang S, Cai Z, Zhu S, Wan J, Jia G, et al.
Plant biotechnology journal (2024) : . 202 003 MeRIP

Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis.
Jia KW, Yao RQ, Fan YW, Zhang DJ, Zhou Y, Wang MJ, Zhang LY, Dong Y, Li ZX, Wang SY, Wang M, et al.
Military Medical Research (2024) 111: 22. 202 003 MeRIP; tested species: human,mouse

A Mettl16/m6A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells.
Han Y, Sun K, Yu S, Qin Y, Zhang Z, Luo J, Hu H, Dai L, Cui M, Jiang C, Liu F, et al.
The EMBO journal (2024) : . 202 003 MeRIP; tested species: human,zebrafish

Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice.
Shen X, Chen M, Zhang J, Lin Y, Gao X, Tu J, Chen K, Zhu A, Xu S
Genes (2024) 153: . 202 003 MeRIP; tested species: mouse

Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, et al.
Frontiers in pharmacology (2024) 15: 1393717. 202 003 MeRIP; tested species: mouse

The m6A reader ECT8 is an abiotic stress sensor that accelerates mRNA decay in Arabidopsis.
Cai Z, Tang Q, Song P, Tian E, Yang J, Jia G
The Plant cell (2024) : . 202 003 MeRIP

Analysis of bacterial transcriptome and epitranscriptome using nanopore direct RNA sequencing.
Tan L, Guo Z, Shao Y, Ye L, Wang M, Deng X, Chen S, Li R
Nucleic acids research (2024) : . 202 003 MeRIP; tested species: e. coli

Tropisetron, an Antiemetic Drug, Exerts an Anti-Epileptic Effect Through the Activation of α7nAChRs in a Rat Model of Temporal Lobe Epilepsy.
Qian X, Sheng X, Ding J, Yiming Z, Zheng J, Zhong J, Zhang T, Li X, He S, Li W, Zhang M, et al.
CNS neuroscience & therapeutics (2024) 3010: e70086. 202 003 MeRIP; tested species: rat

Hypoxic stabilization of RIPOR3 mRNA via METTL3-mediated m6A methylation drives breast cancer progression and metastasis.
Xiong J, Zhou Z, Jiang Y, Li Q, Geng Z, Guo J, Yan C, Zhang J
Oncogene (2024) : . 202 003 MeRIP; tested species: human

RNA methylation sequencing shows different gene expression signatures for response to azacytidine therapy in high-grade myelodysplastic syndromes.
Gulei D, Moisoiu V, Kegyes D, Drula R, Iluta S, Tigu AB, Nistor M, Jitaru C, Bancos A, Rotariu P, Popovici C, et al.
Journal of cellular and molecular medicine (2024) 2818: e70078. 202 003 MeRIP; tested species: human

Identification of key differentially methylated genes regulating muscle development in chickens: insights from Jingyuan breed.
Zhang T, Li J, Hu J, Chen Y, Fu X, Zhao W, Tian J, Yang L, Zhang J
Poultry science (2024) 10312: 104292. 202 003 MeRIP; tested species: chicken

An arms race between 5'ppp-RNA virus and its alternative recognition receptor MDA5 in RIG-I-lost teleost fish.
Geng S, Lv X, Zheng W, Xu T
eLife (2024) 13: . 202 003 MeRIP

m6A Modification Promotes EMT and Metastasis of Castration-Resistant Prostate Cancer by Upregulating NFIB.
Shu F, Liu H, Chen X, Liu Y, Zhou J, Tang L, Cao W, Yang S, Long Y, Li R, Wang H, et al.
Cancer research (2024) 8412: 1947-1962. 202 003 MeRIP; tested species: human

Identification and Characterisation of Potential Targets for N6-methyladenosine (m6A) Modification during Intervertebral Disc Degeneration.
Shen J, Zhang Q, Lan Y, Peng Q, Ji Z, Wu Y, Liu H
Frontiers in bioscience (Landmark edition) (2024) 2912: 405. 202 003 MeRIP; tested species: human

Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis.
Li F, Tao H, Wei Y, Meng R, Li Y, Nie L, Zhang Y, Chang J
Frontiers in bioscience (Landmark edition) (2024) 2912: 421. 202 003 MeRIP; tested species: human

The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry.
Tang R, Duan X, Zhou L, Gao G, Liu J, Wang Y, Shao X, Qin G
Nature communications (2024) 151: 10912. 202 003 MeRIP

N6-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism.
Chen B, Li L, Huang Y, Ma J, Ji F, Chen Y, Wu L, Peng H
Cell reports (2024) 441: 115139. 202 003 MeRIP; tested species: human,mouse

WTAP-dependent N6-methyladenosine methylation of lncRNA TEX41 promotes renal cell carcinoma progression.
Zhou Z, Chen X, Wang H, Ding L, Wang M, Li G, Xia L
Scientific reports (2024) 141: 24742. 202 003 MeRIP; tested species: human

Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia-reperfusion injury.
Wang Q, Liu X, Yuan J, Yang T, Ding L, Song B, Xu Y
Molecular brain (2024) 171: 96. 202 003 MeRIP; tested species: human

Methyltransferase-Like 3-Driven N6-Methyladenosine Modification of Recombination Signal Binding Protein for Immunoglobulin Kappa J Region Promotes Vascular Remodeling in Pulmonary Hypertension.
Du Q, Zhang C, Qu T, Zhou X, Liu Y, Chen Z, Shen Z, Chen P, Zhang R
The American journal of pathology (2024) 19412: 2252-2271. 202 003 MeRIP; tested species: rat

ALKBH5 deletion ameliorates inflammation by regulating IRF3 signaling in an m6A-dependent manner after myocardial infarction.
Zhao X, Liang Z, Zhao W, Tao Y, Hao Y, Liu Y, Wang J, Yu J, Ji H, Jiang H, Xu S, et al.
Biochemical and biophysical research communications (2024) 742: 151039. 202 003 MeRIP; tested species: mouse

Altered m6A RNA methylation profiles in depression implicate the dysregulation of discrete cellular functions in males and females.
Mitsuhashi H, Lin R, Chawla A, Mechawar N, Nagy C, Turecki G
iScience (2024) 2712: 111316. 202 003 MeRIP; tested species: human

Interrogation of the interplay between DNA N6-methyladenosine (6mA) and hypoxia-induced chromatin accessibility by a randomized empirical model (EnrichShuf).
Lai JC, Hsu KW, Wu KJ
Nucleic acids research (2024) : . 202 003 MeRIP; tested species: human

METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma.
Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig MH, Mendez A, Burgos-Panadero R, Höppner S, Bartenhagen C, Sjövall D, et al.
The EMBO journal (2024) : . 202 003 MeRIP; tested species: human

Transcriptome-wide methylated RNA immunoprecipitation sequencing profiling reveals m6A modification involved in response to heat stress in Apostichopus japonicus.
Sun Y, Sun Y, He X, Li S, Xu X, Feng Y, Yang J, Xie R, Sun G
BMC genomics (2024) 251: 1071. 202 003 MeRIP

DHX36 binding induces RNA structurome remodeling and regulates RNA abundance via m6A reader YTHDF1.
Zhang Y, Zhao J, Chen X, Qiao Y, Kang J, Guo X, Yang F, Lyu K, Ding Y, Zhao Y, Sun H, et al.
Nature communications (2024) 151: 9890. 202 003 MeRIP; tested species: human,mouse

N6-Methyladenosine RNA Modification Regulates Maize Resistance to Maize Chlorotic Mottle Virus Infection.
Xia Z, Zhang S, Guo H, Gao X, Hao K, Dong X, Guo J, Li J, Wang Z, An M, Wu Y, et al.
Journal of agricultural and food chemistry (2024) 7239: 21935-21945. 202 003 MeRIP

METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism.
Jia X, Liu S, Sun C, Zhu M, Yuan Q, Wang M, Xu T, Wang Z, Chen Z, Huang M, Ji N, et al.
Ecotoxicology and environmental safety (2024) 289: 117518. 202 003 MeRIP; tested species: human,mouse

Huyang Yangkun formula regulates the mitochondria pathway of ovarian granulosa cell apoptosis through FTO/m6A-P53 pathway.
Li Y, Wang L, Liu J, Nie G, Yang H
Frontiers in pharmacology (2024) 15: 1491546. 202 003 MeRIP; tested species: rat

Dynamics of epitranscriptomes uncover translational reprogramming directed by ac4C in rice during pathogen infection.
Lu X, He Y, Guo JQ, Wang Y, Yan Q, Xiong Q, Shi H, Hou Q, Yin J, An YB, Chen YD, et al.
Nature plants (2024) : . 202 003 MeRIP

FTO-mediated DSP m6A demethylation promotes an aggressive subtype of growth hormone-secreting pituitary neuroendocrine tumors.
Zou Y, Bao X, Li D, Ye Z, Xiang R, Yang Y, Zhu Z, Chen Z, Zeng L, Xue C, Zhao H, et al.
Molecular cancer (2024) 231: 205. 202 003 MeRIP; tested species: human

Investigating the mechanism of METTL16-dependent m6A modification regulating the SAMD11 protein signaling pathway to inhibit thyroid cancer phenotypes.
Liu Y, Wu G, Tao X, Dong J, Shi T, Shi C
International journal of biological macromolecules (2024) 280Pt 4: 136176. 202 003 MeRIP; tested species: mouse

The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis.
Liu Y, Li J, Wang C, Li J, Luo K, Tao K, Tian Y, Song X, Zhai Z, Tao Y, You J, et al.
BMC biology (2024) 221: 192. 202 003 MeRIP; tested species: mouse

The METHYLTRANSFERASE B-SERRATE interaction mediates the reciprocal regulation of microRNA biogenesis and RNA m6A modification.
Bai H, Dai Y, Fan P, Zhou Y, Wang X, Chen J, Jiao Y, Du C, Huang Z, Xie Y, Guo X, et al.
Journal of integrative plant biology (2024) : . 202 003 MeRIP

Optimizing ABA-based chemically induced proximity for enhanced intracellular transcriptional activation and modification response to ABA.
Zhou Z, Wang YQ, Zheng XN, Zhang XH, Ji LY, Han JY, Zuo ZC, Mo WL, Zhang L
Science China. Life sciences (2024) : . 202 003 MeRIP; tested species: human

Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline.
Zheng XM, Zhang XD, Tan LL, Zhang J, Wang TT, Ling Q, Wang H, Ouyang KW, Wang KW, Chang W, Li H, et al.
Ecotoxicology and environmental safety (2024) 284: 116884. 202 003 MeRIP; tested species: mouse

TMK4-mediated FIP37 phosphorylation regulates auxin-triggered N6-methyladenosine modification of auxin biosynthetic genes in Arabidopsis.
Li B, Zhou Q, Cai L, Li L, Xie C, Li D, Zhu F, Li X, Zhao X, Liu X, Shen L, et al.
Cell reports (2024) 438: 114597. 202 003 MeRIP

eIF2Bβ confers resistance to Turnip mosaic virus by recruiting ALKBH9B to modify viral RNA methylation.
Sha T, Li Z, Xu S, Su T, Shopan J, Jin X, Deng Y, Lyu X, Hu Z, Zhang M, Yang J, et al.
Plant biotechnology journal (2024) 2211: 3205-3217. 202 003 MeRIP

N6-methyladenosine facilitates arsenic-induced neoplastic phenotypes of human bronchial epithelial cells by promoting miR-106b-5p maturation.
Chen B, Wang L, Li L, Zhou M, Pan S, Wang Q, Hou Y, Zhou X
Ecotoxicology and environmental safety (2024) 283: 116803. 202 003 MeRIP; tested species: human

N6-Methyladenosine (m6A) Sequencing Reveals Heterodera glycines-Induced Dynamic Methylation Promoting Soybean Defense.
Qin R, Huang M, Jiang Y, Jiang D, Chang D, Xie Y, Dou Y, Wu L, Wei L, Wang M, Tian Z, et al.
Phytopathology (2024) 1147: 1612-1625. 202 003 MeRIP

Foot-and-mouth disease virus 2B protein antagonizes STING-induced antiviral activity by targeting YTHDF2.
Xue Q, Ma K, Yang F, Liu H, Cao W, Liu P, Zhu Z, Zheng H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2024) 3823: e70224. 202 003 MeRIP; tested species: mouse

WTAP/IGF2BP3 mediated m6A modification of the EGR1/PTEN axis regulates the malignant phenotypes of endometrial cancer stem cells.
Wang B, Wang Y, Wang W, Wang Z, Zhang Y, Pan X, Wen X, Leng H, Guo J, Ma XX
Journal of experimental & clinical cancer research : CR (2024) 431: 204. 202 003 MeRIP; tested species: human

N6-methyladenosine writer METTL16-mediated alternative splicing and translation control are essential for murine spermatogenesis.
Ma Q, Gui Y, Ma X, Zhang B, Xiong W, Yang S, Cao C, Mo S, Shu G, Ye J, Liu K, et al.
Genome biology (2024) 251: 193. 202 003 MeRIP; tested species: mouse

Histone lactylation-driven YTHDC1 promotes hepatocellular carcinoma progression via lipid metabolism remodeling.
Du W, Tan S, Peng Y, Lin S, Wu Y, Ding K, Chen C, Liu R, Cao Y, Li Z, Gu S, et al.
Cancer letters (2024) 611: 217426. 202 003 MeRIP; tested species: human

m6A modification enhances the stability of CDC25A promotes tumorigenicity of esophagogastric junction adenocarcinoma via cell cycle.
Pan Y, Feng H, Zhou J, Zhang W, Liu Y, Zheng J, Wang J, Gao S, Li Y
International journal of biological sciences (2024) 2011: 4209-4221. 202 003 MeRIP; tested species: human

Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, et al.
Heliyon (2024) 1021: e38650. 202 003 MeRIP; tested species: human

The functional role of m6A demethylase ALKBH5 in cardiomyocyte hypertrophy.
Meng C, Su H, Shu M, Shen F, Lu Y, Wu S, Su Z, Yu M, Yang D
Cell death & disease (2024) 159: 683. 202 003 MeRIP; tested species: rat

Characterization of ACTN4 as a novel antiviral target against SARS-CoV-2.
Zhu M, Huang F, Sun H, Liu K, Chen Z, Yu B, Hao H, Liu H, Ding S, Zhang X, Liu L, et al.
Signal transduction and targeted therapy (2024) 91: 243. 202 003 MeRIP; tested species: human

TRPML1 ameliorates seizures-related neuronal injury by regulating autophagy and lysosomal biogenesis via Ca2+/TFEB signaling pathway.
Peng T, Xie Y, Zhao S, Wang X, Zhang W, Xie Y, Wang C, Xie N
Biochimica et biophysica acta. Molecular basis of disease (2024) 18708: 167477. 202 003 MeRIP; tested species: mouse

Nuclear retention coupled with sequential polyadenylation dictates post-transcriptional m6A modification in the nucleus.
Tang P, Yang J, Chen Z, Du C, Yang Y, Zhao H, Huang L, Li G, Liu F, Dong B, Shan T, et al.
Molecular cell (2024) : . 202 003 MeRIP; tested species: human

m6Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiation.
An H, Hong Y, Goh YT, Koh CWQ, Kanwal S, Zhang Y, Lu Z, Yap PML, Neo SP, Wong CM, Wong AST, et al.
Molecular cell (2024) 8421: 4142-4157.e14. 202 003 MeRIP; tested species: human

Multi-omics analysis unveils early molecular responses to aluminum toxicity in barley root tip.
Wu L, Chen J, Yan T, Fu B, Wu D, Kuang L
Plant physiology and biochemistry : PPB (2024) 217: 109209. 202 003 MeRIP

Dynamic m6A mRNA methylation reveals the involvement of AcALKBH10 in ripening-related quality regulation in kiwifruit.
Su D, Shu P, Hu N, Chen Y, Wu Y, Deng H, Du X, Zhang X, Wang R, Li H, Zeng Y, et al.
The New phytologist (2024) 2436: 2265-2278. 202 003 MeRIP

N6-methyladenosine transcriptome-wide profiles of maize kernel development.
Wu JW, Zheng GM, Zhang L, Zhao YJ, Yan RY, Ren RC, Wei YM, Li KP, Zhang XS, Zhao XY
Plant physiology (2024) : . 202 003 MeRIP

Defining context-dependent m6A RNA methylomes in Arabidopsis.
Zhang B, Zhang S, Wu Y, Li Y, Kong L, Wu R, Zhao M, Liu W, Yu H
Developmental cell (2024) : . 202 003 MeRIP

Targeting FTO suppresses hepatocellular carcinoma by inhibiting ERBB3 and TUBB4A expression.
Jiang L, Liang R, Luo Q, Chen Z, Song G
Biochemical pharmacology (2024) 226: 116375. 202 003 MeRIP; tested species: human

YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
Wang S, Xu L, Wang D, Zhao S, Li K, Ma F, Yao Q, Zhang Y, Wu Z, Shao Y, Song S, et al.
Cancer letters (2024) 597: 217047. 202 003 MeRIP; tested species: human

N6-methyladenosine dynamics in placental development and trophoblast functions, and its potential role in placental diseases.
Wu S, Liu K, Cui Y, Zhou B, Zhao H, Xiao X, Zhou Q, Ma D, Li X
Biochimica et biophysica acta. Molecular basis of disease (2024) 18707: 167290. 202 003 MeRIP; tested species: human

Profiling of m6A methylation in porcine intramuscular adipocytes and unravelling PHKG1 represses porcine intramuscular lipid deposition in an m6A-dependent manner.
Chao M, Wang M, Han H, Liu Y, Sun X, Tian T, Pang W, Cai R
International journal of biological macromolecules (2024) 272Pt 1: 132728. 202 003 MeRIP; tested species: pig

Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome.
Liu K, He X, Huang J, Yu S, Cui M, Gao M, Liu L, Qian Y, Xie Y, Hui M, Hong Y, et al.
Clinical epigenetics (2023) 151: 86. 202 003 MeRIP; tested species: human

GPX8 deficiency-induced oxidative stress reprogrammed m6A epitranscriptome of oral cancer cells.
Chen X, Yuan L, Zhang L, Chen L, He Y, Wang C, Wu J, Chen S, Zhao W, Yu D
Epigenetics (2023) 181: 2208707. 202 003 MeRIP; tested species: human

Comprehensive analysis of transcriptome-wide M6A methylation for hepatic ischaemia reperfusion injury in mice.
Hua Y, Li X, Yin B, Huang J, Lu S, Wang C, Ke S, Xu Y, Qian B, Feng Z, Yu H, et al.
Epigenetics (2023) 181: 2201716. 202 003 MeRIP; tested species: mouse

Modification and Expression of mRNA m6A in the Lateral Habenular of Rats after Long-Term Exposure to Blue Light during the Sleep Period.
Li Y, Ren J, Zhang Z, Weng Y, Zhang J, Zou X, Wu S, Hu H
Genes (2023) 141: . 202 003 MeRIP; tested species: rat

Transcriptome-wide analysis of RNA m6A methylation regulation of muscle development in Queshan Black pigs.
Dou Y, Wei Y, Zhang Z, Li C, Song C, Liu Y, Qi K, Li X, Li X, Qiao R, Wang K, et al.
BMC genomics (2023) 241: 239. 202 003 MeRIP; tested species: pig

KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo-YAP pathway.
Chen X, Lu T, Cai Y, Han Y, Ding M, Chu Y, Zhou X, Wang X
Cellular & molecular biology letters (2023) 281: 32. 202 003 MeRIP; tested species: human

METTL3 and METTL14-mediated N6-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis.
Shen L, Zhang C, Zhang Y, Yang Y
Reproductive biomedicine online (2023) 462: 255-265. 202 003 MeRIP; tested species: human

Integrated analysis of transcriptome-wide m6A methylation in a Cd-induced kidney injury rat model.
Li S, Zhou H, Liang Y, Yang Q, Zhang J, Shen W, Lei L
Ecotoxicology and environmental safety (2023) 256: 114903. 202 003 MeRIP; tested species: rat

N6-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.
Ji D, Hu C, Ning J, Ying X, Zhang H, Zhang B, Liu B, Liu Q, Ji W, Zhang R
Ecotoxicology and environmental safety (2023) 254: 114755. 202 003 MeRIP; tested species: human

Targeted m6A demethylation of ITGA6 mRNA by a multisite dCasRx-m6A editor inhibits bladder cancer development.
Ying X, Huang Y, Liu B, Hu W, Ji D, Chen C, Zhang H, Liang Y, Lv Y, Ji W
Journal of advanced research (2023) : . 202 003 MeRIP; tested species: human

METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition.
Wang Y, Chen Y, Liang J, Jiang M, Zhang T, Wan X, Wu J, Li X, Chen J, Sun J, Hu Y, et al.
Journal of molecular cell biology (2023) : . 202 003 MeRIP; tested species: mouse

Transcriptome-Wide Study Revealed That N6-Methyladenosine Participates in Regulation Meat Production in Goats.
Zou J, Shen Y, Zou J, Yu J, Jiang Y, Huang Y, Jiang Q
Foods (Basel, Switzerland) (2023) 126: . 202 003 MeRIP

N6-Methyladenosine RNA Modifications Regulate the Response to Platinum Through Nicotinamide N-methyltransferase.
Huang H, Zhao G, Cardenas H, Valdivia AF, Wang Y, Matei D
Molecular cancer therapeutics (2023) 223: 393-405. 202 003 MeRIP; tested species: human

The Tumorigenic Effect of lncRNA AFAP1-AS1 is Mediated by Translated Peptide ATMLP Under the Control of m6 A Methylation.
Pei H, Dai Y, Yu Y, Tang J, Cao Z, Zhang Y, Li B, Nie J, Hei TK, Zhou G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023) : e2300314. 202 003 MeRIP; tested species: human

The role of m6A demethylase FTO in chemotherapy resistance mediating acute myeloid leukemia relapse.
Zhang ZW, Zhao XS, Guo H, Huang XJ
Cell death discovery (2023) 91: 225. 202 003 MeRIP; tested species: human

Changes in the m6A RNA methylome accompany the promotion of soybean root growth by rhizobia under cadmium stress.
Han X, Wang J, Zhang Y, Kong Y, Dong H, Feng X, Li T, Zhou C, Yu J, Xin D, Chen Q, et al.
Journal of hazardous materials (2023) 441: 129843. 202 003 MeRIP

Differential methylation of circRNA m6A in an APP/PS1 Alzheimer's disease mouse model.
Zhang X, Yang S, Han S, Sun Y, Han M, Zheng X, Li F, Wei Y, Wang Y, Bi J
Molecular medicine reports (2023) 272: . 202 003 MeRIP; tested species: mouse

Transcriptome-wide profiling of mRNA N6-methyladenosine modification in rice panicles and flag leaves.
Wang L, Yang C, Shan Q, Zhao M, Yu J, Li YF
Genomics (2023) 1151: 110542. 202 003 MeRIP

METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling.
Wan S, Sun Y, Zong J, Meng W, Yan J, Chen K, Wang S, Guo D, Xiao Z, Zhou Q, Yin Z, et al.
Cell death & disease (2023) 146: 349. 202 003 MeRIP; tested species: mouse

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism.
Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel SP, et al.
Cell stem cell (2023) 301: 52-68.e13. 202 003 MeRIP; tested species: human

K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis.
Zhang XL, Chen XH, Xu B, Chen M, Zhu S, Meng N, Wang JZ, Zhu H, Chen D, Liu JB, Yan GR, et al.
Nature communications (2023) 141: 3815. 202 003 MeRIP; tested species: human

N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration.
Chen Z, Song J, Xie L, Xu G, Zheng C, Xia X, Lu F, Ma X, Zou F, Jiang J, Wang H, et al.
Cell death and differentiation (2023) 308: 1957-1972. 202 003 MeRIP; tested species: human

Promoting axon regeneration by inhibiting RNA N6-methyladenosine demethylase ALKBH5.
Wang D, Zheng T, Zhou S, Liu M, Liu Y, Gu X, Mao S, Yu B
eLife (2023) 12: . 202 003 MeRIP; tested species: mouse,rat

ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control.
Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, et al.
Cell reports (2023) 4210: 113163. 202 003 MeRIP; tested species: mouse

Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice.
Zeng F, Cao J, Hong Z, Lu Y, Qin Z, Tao T
Neural regeneration research (2023) 1811: 2545-2552. 202 003 MeRIP; tested species: human

N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Chen B, Huang Y, He S, Yu P, Wu L, Peng H
Cell chemical biology (2023) 302: 144-158.e10. 202 003 MeRIP; tested species: mouse

A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth.
Miyake K, Costa Cruz PH, Nagatomo I, Kato Y, Motooka D, Satoh S, Adachi Y, Takeda Y, Kawahara Y, Kumanogoh A
Cell reports (2023) 427: 112688. 202 003 MeRIP; tested species: human

Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma.
Pan Y, Lu X, Shu G, Cen J, Lu J, Zhou M, Huang K, Dong J, Li J, Lin H, Song H, et al.
Cancer research (2023) 831: 103-116. 202 003 MeRIP; tested species: human,mouse

Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability.
Uzonyi A, Dierks D, Nir R, Kwon OS, Toth U, Barbosa I, Burel C, Brandis A, Rossmanith W, Le Hir H, Slobodin B, et al.
Molecular cell (2023) 832: 237-251.e7. 202 003 MeRIP; tested species: human

N6-methyladenosine modification promotes hepatocarcinogenesis through circ-CDYL-enriched and EpCAM-positive liver tumor-initiating exosomes.
Wei Y, Fu J, Zhang H, Ling Y, Tang X, Liu S, Yu M, Liu F, Zhuang G, Qian H, Zhang K, et al.
iScience (2023) 2610: 108022. 202 003 MeRIP; tested species: human,mouse

Transcriptome-wide m6A methylation in natural yellow leaf of Catalpa fargesii.
Zhang Y, Wang J, Ma W, Lu N, Fu P, Yang Y, Zhao L, Hu J, Qu G, Wang N
Frontiers in plant science (2023) 14: 1167789. 202 003 MeRIP

Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation.
Wei T, Li J, Zhang J, Zhang Q, Liu X, Chen Q, Wen L, Ma K, Chen W, Zhao J, Zhang C, et al.
Cell reports (2023) 427: 112704. 202 003 MeRIP; tested species: mouse

Single-cell m6A mapping in vivo using picoMeRIP-seq.
Li Y, Wang Y, Vera-Rodriguez M, Lindeman LC, Skuggen LE, Rasmussen EMK, Jermstad I, Khan S, Fosslie M, Skuland T, Indahl M, et al.
Nature biotechnology (2023) : . 202 003 MeRIP; tested species: human,zebrafish

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, et al.
Nature neuroscience (2013) 168: 1042-8. 202 003 MeRIP

RNA-methylation-dependent RNA processing controls the speed of the circadian clock.
Fustin JM, Doi M, Yamaguchi Y, Hida H, Nishimura S, Yoshida M, Isagawa T, Morioka MS, Kakeya H, Manabe I, Okamura H, et al.
Cell (2013) 1554: 793-806. 202 003 MeRIP

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.
Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, Sorek R, et al.
Nature (2012) 4857397: 201-6. 202 003 MeRIP

Differential staining of preneoplastic foci in rat liver parenchyma during azo dye carcinogenesis.
Brière N
Histochemie. Histochemistry. Histochimie (1971) 262: 113-9. 202 003 MeRIP

Cat. No.: 202 003

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Epitranscriptomic Regulation of Platinum Resistance via the METTL3-ADAM23 Axis in Ovarian Cancer.
Kim U, Li J, Matei D, Huang H
Cells (2026) 153: . 202 003 Dot blot; tested species: human

FTO promotes bladder cancer progression and stemness-associated phenotypes.
Wu N, He X
Cytotechnology (2026) 783: 103. 202 003 Dot blot; tested species: human

Acute exercise promotes WAT browning by remodeling mRNA m6A methylation.
Chen W, Liu Y, Liu J, Chen Y, Wang X
Life sciences (2025) 361: 123269. 202 003 Dot blot; tested species: mouse

Evaluation of N 6-methyldeoxyadenosine antibody-based genomic profiling in eukaryotes.
Debo BM, Mallory BJ, Stergachis AB
Genome research (2023) 333: 427-434. 202 003 Dot blot

Structural basis for MTA1c-mediated DNA N6-adenine methylation.
Chen J, Hu R, Chen Y, Lin X, Xiang W, Chen H, Yao C, Liu L
Nature communications (2022) 131: 3257. 202 003 Dot blot

Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA.
Zhang M, Yang S, Nelakanti R, Zhao W, Liu G, Li Z, Liu X, Wu T, Xiao A, Li H
Cell research (2020) : . 202 003 Dot blot

Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication.
Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C
Plant physiology (2019) : . 202 003 Dot blot, IP

Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer.
Wang X, Li Z, Kong B, Song C, Cong J, Hou J, Wang S
Oncotarget (2017) 858: 98918-98930. 202 003 Dot blot

DNA N6-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs.
Zhou C, Liu Y, Li X, Zou J, Zou S
Bone research (2016) 4: 16033. 202 003 Dot blot

Genome-wide detection of high abundance N6-methyladenosine sites by microarray.
Li Y, Wang Y, Zhang Z, Zamudio AV, Zhao JC
RNA (New York, N.Y.) (2015) 218: 1511-8. 202 003 Dot blot

DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 Dot blot, IP

Correlations of m6A methylation-related mRNAs with thyroid cancer.
Jiang Z, Luo S, Lin Y, Zhang H, Yi R
Scientific reports (2026) 161: 5688. 202 003 IP; tested species: human

Cell type-specific regulation of m6 A modified RNAs in the aging Drosophila brain.
Perlegos AE, Byrns CN, Bonini NM
Aging cell (2024) : e14076. 202 003 IP; tested species: drosophila

Changes in m6A RNA methylation are associated with male sterility in wolfberry.
Zhao J, Zhang C, Li S, Yuan M, Mu W, Yang J, Ma Y, Guan C, Ma C
BMC plant biology (2023) 231: 456. 202 003 IP

Transcriptome-wide N6-methyladenosine methylation profile of atherosclerosis in mice.
Zheng X, Zhou B, Li Y, Zhong H, Huang Z, Gu M
BMC genomics (2023) 241: 774. 202 003 IP; tested species: mouse

The m6A(m)-independent role of FTO in regulating WNT signaling pathways.
Kim H, Jang S, Lee YS
Life science alliance (2022) 55: . 202 003 IP; tested species: human

Chronic allergic asthma alters m6A epitranscriptomic tagging of mRNAs and lncRNAs in the lung.
Ni X, Li X, Hu B, Wang L
Bioscience reports (2022) 4212: . 202 003 IP; tested species: mouse

m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation.
Boo SH, Ha H, Kim YK
Cell reports (2022) 4010: 111317. 202 003 IP; tested species: human

RNA m6A Modification Changes in Postmortem Nucleus Accumbens of Subjects with Alcohol Use Disorder: A Pilot Study.
Liu Y, Zhang H
Genes (2022) 136: . 202 003 IP; tested species: human

Alteration of the m6A methylation landscape in a mouse model of scleroderma.
Shen L, Yu Y, Jiang M, Zhao J
Epigenomics (2021) : . 202 003 IP; tested species: mouse

R-loop resolution promotes co-transcriptional chromatin silencing.
Xu C, Wu Z, Duan HC, Fang X, Jia G, Dean C
Nature communications (2021) 121: 1790. 202 003 IP

Dynamic landscape and evolution of m6A methylation in human.
Zhang H, Shi X, Huang T, Zhao X, Chen W, Gu N, Zhang R
Nucleic acids research (2020) : . 202 003 IP; tested species: human

Antibody-free enzyme-assisted chemical approach for detection of N6-methyladenosine.
Wang Y, Xiao Y, Dong S, Yu Q, Jia G
Nature chemical biology (2020) : . 202 003 IP; tested species: human,mouse

Profiling of RNA N6-methyladenosine methylation during follicle selection in chicken ovary.
Fan Y, Zhang C, Zhu G
Poultry science (2019) : . 202 003 IP; tested species: chicken

Genome-wide identification of mRNA 5-methylcytosine in mammals.
Huang T, Chen W, Liu J, Gu N, Zhang R
Nature structural & molecular biology (2019) 265: 380-388. 202 003 IP; tested species: human

RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening.
Zhou L, Tian S, Qin G
Genome biology (2019) 201: 156. 202 003 IP

Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication.
Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C
Plant physiology (2019) : . 202 003 Dot blot, IP

Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes.
Koh CWQ, Goh YT, Goh WSS
Nature communications (2019) 101: 5636. 202 003 IP; tested species: human

RNA Modification Level Estimation with pulseR.
Boileau E, Dieterich C
Genes (2018) 912: . 202 003 IP; tested species: human

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
Tsai K, Courtney DG, Cullen BR
PLoS pathogens (2018) 142: e1006919. 202 003 IP

Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation.
Koziol MJ, Bradshaw CR, Allen GE, Costa AS, Frezza C
Bio-protocol (2016) 621: . 202 003 IP

The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells.
Lin S, Choe J, Du P, Triboulet R, Gregory RI
Molecular cell (2016) 623: 335-345. 202 003 IP; tested species: human

N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T
Nature (2015) 5187540: 560-4. 202 003 IP

Widespread occurrence of N6-methyladenosine in bacterial mRNA.
Deng X, Chen K, Luo GZ, Weng X, Ji Q, Zhou T, He C
Nucleic acids research (2015) 4313: 6557-67. 202 003 IP; tested species: e. coli

N6-adenosine methylation in MiRNAs.
Berulava T, Rahmann S, Rademacher K, Klein-Hitpass L, Horsthemke B
PloS one (2015) 102: e0118438. 202 003 IP

DNA Methylation on N6-Adenine in C. elegans.
Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y
Cell (2015) 1614: 868-78. 202 003 Dot blot, IP

N6-methyladenosine marks primary microRNAs for processing.
Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF
Nature (2015) 5197544: 482-5. 202 003 IP

DamIP: using mutant DNA adenine methyltransferase to study DNA-protein interactions in vivo.
Xiao R, Moore DD
Current protocols in molecular biology (2011) Chapter 21: Unit21.21. 202 003 IP

Antibodies specific for N6-methyladenosine react with intact snRNPs U2 and U4/U6.
Bringmann P, Lührmann R
FEBS letters (1987) 2132: 309-15. 202 003 IP

Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development.
Kwon J, Jo YJ, Namgoong S, Kim NH
Scientific reports (2019) 91: 8640. 202 003 ICC; tested species: mouse

202 003 IHC; tested species: mouse

N6-methyladenosine (m6A) modification of TXNIP in 3'UTR instigates abdominal aorta aneurysm in mice.
Hantelys F, Yin W, Zou MH
iScience (2026) 292: 114630. 202 003 MeRIP; tested species: human

The LkMTA2/LkMTB8-LkERF1-LkEXPA8 cascade regulates xylem cell expansion in larch.
Lyu Z, Xie Y, Zhang K, Han H, Zhang S, Sun X
The New phytologist (2026) 2503: 1535-1550. 202 003 MeRIP

NERD-dependent m6A modification of the nascent FLC transcript regulates flowering time in Arabidopsis.
Shao Y, Ma J, Zhang S, Xu Y, Yu H
Nature plants (2025) 113: 468-482. 202 003 MeRIP

Transcriptome-wide study of mRNAs modified by m6A RNA methylation in the testis development of dairy goats.
Ren X, Qu Y, Shari A, Li G
Animal biotechnology (2025) 361: 2496641. 202 003 MeRIP

Synergistic function of RNA modifications in Arabidopsis and rice.
Ma A, Wang S, He X, Qu Y, Xie S, Gao J, Peng Y, Shen L, Pu W, He C
aBIOTECH (2025) 64: 803-815. 202 003 MeRIP

Redox modification of m6A demethylase SlALKBH2 in tomato regulates fruit ripening.
Zhou L, Gao G, Tang R, Liu J, Wang Y, Liang Z, Tian S, Qin G
Nature plants (2025) 112: 218-233. 202 003 MeRIP

mRNA m6A regulates gene expression via H3K4me3 shift in 5' UTR.
Yang Y, Huang Y, Wang T, Li S, Jiang J, Chen S, Chen F, Wang L
Genome biology (2025) 261: 54. 202 003 MeRIP

Dam-dependent epigenetic memory regulates prophage reintegration in Salmonella.
Yang J, Son Y, Park J, Park W
Nucleic acids research (2025) 5318: . 202 003 MeRIP

Morphine-Driven m6A Epitranscriptomic Neuroadaptations in Primary Cortical Cultures.
Dabrowski KR, Daws SE
Molecular neurobiology (2024) : . 202 003 MeRIP; tested species: rat

Genome-wide screening of m6A profiling of cutaneous wound healing in diabetic mice.
Shen J, Chen H, Dai J
Molecular biology reports (2024) 511: 175. 202 003 MeRIP; tested species: mouse

RNA N6-Methyladenosine Affects Copper-Induced Oxidative Stress Response in Arabidopsis thaliana.
Sharma B, Govindan G, Li Y, Sunkar R, Gregory BD
Non-coding RNA (2024) 101: . 202 003 MeRIP

Programmable RNA N6 -methyladenosine editing with CRISPR/dCas13a in plants.
Shi C, Zou W, Liu X, Zhang H, Li X, Fu G, Fei Q, Qian Q, Shang L
Plant biotechnology journal (2024) : . 202 003 MeRIP

The m6A reader ECT8 is an abiotic stress sensor that accelerates mRNA decay in Arabidopsis.
Cai Z, Tang Q, Song P, Tian E, Yang J, Jia G
The Plant cell (2024) : . 202 003 MeRIP

An arms race between 5'ppp-RNA virus and its alternative recognition receptor MDA5 in RIG-I-lost teleost fish.
Geng S, Lv X, Zheng W, Xu T
eLife (2024) 13: . 202 003 MeRIP

The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry.
Tang R, Duan X, Zhou L, Gao G, Liu J, Wang Y, Shao X, Qin G
Nature communications (2024) 151: 10912. 202 003 MeRIP

Defining context-dependent m6A RNA methylomes in Arabidopsis.
Zhang B, Zhang S, Wu Y, Li Y, Kong L, Wu R, Zhao M, Liu W, Yu H
Developmental cell (2024) : . 202 003 MeRIP

Transcriptome-wide profiling of mRNA N6-methyladenosine modification in rice panicles and flag leaves.
Wang L, Yang C, Shan Q, Zhao M, Yu J, Li YF
Genomics (2023) 1151: 110542. 202 003 MeRIP

Differential staining of preneoplastic foci in rat liver parenchyma during azo dye carcinogenesis.
Brière N
Histochemie. Histochemistry. Histochimie (1971) 262: 113-9. 202 003 MeRIP

Dot blot
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ELISA
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Background

m6A (N6-methyladenosine) is a posttranscriptional RNA-modification found throughout all kingdoms, e.g. in vertebrate snRNAs U2, U4, U6, in viral and eukaryotic mRNAs, and in E. coli 16S rRNA.
Recent studies have found that mRNA is predominately m6A modified at stop codons and long internal exons, which are conserved between mouse and human. The so-called RNA methylome probably plays an important role in in the regulation of gene expression.
In E. coli Dam methylase introduces m6A modifications on the DNA level at the 5'-GATC-3' motif. This allows the cell to differentiate between the parental and the daughter strand during mismatch repair.

1 ) Bringmann P et al., FEBS Lett. (1987)
2 ) Warda AS et al., EMBO Rep. (2017)
3 ) Xiang Y et al., Nature (2017)
4 ) Koziol MJ et al., Bio Protoc (2016)
5 ) Koziol MJ et al., Nat. Struct. Mol. Biol. (2016)
6 ) Gokhale NS et al., Cell Host Microbe (2016)
7 ) Li X et al., Int J Mol Sci (2016)
8 ) Molinie B et al., Nat. Methods (2016)
9 ) Mishima E et al., PLoS ONE (2015)
10 ) Li Y et al., RNA (2015)

Protocols

Other products for this target

m6A antibody - 202 003

References for m6A - 202 003