Home|||||||Technical Support|

alpha-Protocadherin - 190 002

A group of cell adhesion molecules
Polyclonal rabbit antiserum
Cat. No.: 190 002
Amount: 200 µl
Price: $350.00
Cat. No. 190 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 500 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not recommended (see remarks)
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 796 to 946 from rat α-Protocadherin (UniProt Id: Q767I8)
Reactivity Reacts with: human, rat (Q767I8), mouse (O88689).
Other species not tested yet.
Specificity Detects all α-protocadherins since they share the constant cytoplasmic tail.
Remarks

ICC: cat. no. 190 003 is recommended

Data sheet 190_002.pdf
Cat. No.: 190 002
Quantity: 200 µl
Price: $350.00
Background
Cadherins are a complex protein superfamily involved in many cellular processes including cell recognition, cell signaling, cell communication during embryogenesis, and the formation of neural circuits in the central nervous system. Protocadherins constitute the largest group within the cadherin superfamily and can be subdivided into three groups: α-, β- and γ-protocadherins. Genes for these subgroups are organized in closely related gene clusters and encode variable extracellular and transmembrane domains. The short cytosolic tails are constant and shared within one subgroup.