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Neurofilament M antibody - 171 248

Neurofilaments are major neuronal intermediate filaments
Rabbit monoclonal recombinant IgG
Cat. No.: 171 248
Amount: 50 µg
Price: $415.00
Cat. No. 171 248 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Clone Rb103H5A1
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 761 to 846 from rat Neurofilament M (UniProt Id: P12839)
Specificity Specific for Neurofilament M
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 103H5A1. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 171_248.pdf
Cat. No.: 171 248
Amount: 50 µg
Price: $415.00
Background
Neurofilaments are exclusively expressed in nerve cells and are the major structural component of large-diameter myelinated axons. They are predominatly composed of three proteins, Neurofilament H, L and M and are among the most highly phosphorylated neuronal proteins.