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Neurofilament H antibody - 171 138

Neurofilaments are major neuronal intermediate filaments
Guinea pig monoclonal recombinant IgG
Cat. No.: 171 138
Amount: 50 µg
Price: $415.00
Cat. No. 171 138 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 1000 up to 1 : 5000 gallery  
Clone Gp3A2D1
Subtype IgG2 (κ light chain)
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of mouse Neurofilament H (UniProt Id: P19246)
Reactivity Reacts with: mouse (P19246), rat (P16884).
Other species not tested yet.
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody 3A2D1. The constant regions of the heavy and light chains have been replaced with guinea pig specific sequences. Therefore, the antibody can be used with standard anti-guinea pig secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 171_138.pdf
Cat. No.: 171 138
Amount: 50 µg
Price: $415.00
Background
Neurofilaments are exclusively expressed in nerve cells and are the major structural component of large-diameter myelinated axons. They are predominatly composed of three proteins, Neurofilament H, L and M and are among the most highly phosphorylated neuronal proteins.