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Synaptopodin antibody - 163 011 K.O.

Synaptopodin is an actin associated protein present in renal podocytes and telencephalic dendrites
Mouse monoclonal purified IgG
Cat. No.: 163 011
Amount: 100 µg
Price: $415.00
Cat. No. 163 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 200 up to 1 : 1000 (see remarks) gallery  
Clone 109C1D3
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 374 to 495 from mouse Synaptopodin (UniProt Id: Q8CC35)
Reactivity Reacts with: mouse (Q8N3V7), rat (Q9Z327), human (Q8N3V7).
Other species not tested yet.
Specificity Specific for Synaptopodin. Fragment used for immunization is present in all 3 isoforms. K.O. validated
Matching control protein/peptide 163-0P

IHC-P: A higher concentration (1 : 200) is recommended for human tissue samples.

Data sheet 163_011.pdf
Cat. No.: 163 011
Amount: 100 µg
Price: $415.00
Synaptopodin is the founding member of a new class of proline-rich actin-associated proteins. Up to now three splice variants of synaptopodin have been identified. In neurons and podocytes the protein is expressed in a differentiation dependent manner.
Synaptopodin deficient mice lack the dendritic spine apparatus and exhibit impaired activity-dependent long-term synaptic plasticity.