Cat. No.: 162 306
Amount: 50 µg
Price:
$380.00
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| Cat. No. 162 306 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to residues near the carboxy terminus of rat Shank3 (UniProt Id: Q9JLU4) |
| Reactivity |
Reacts with: rat (Q9JLU4), mouse (Q4ACU6). Other species not tested yet. |
| Specificity | Specific for Shank 3 with weak cross-reactivity to Shank 1 and Shank 2. |
| Remarks |
IHC-Fr: Fixation with acetone or PFA/formaldehyde is recommended. Postfixation with methanol is not advised. |
| Data sheet | 162_306.pdf |
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Shank1, 2 and 3 are major proteins of the postsynaptic density (PSD). They are composed of several protein-protein interaction domains like PDZ-, homer- and ABP1-binding domains which allow them to crosslink ionotopic and metabotropic glutamate receptor complexes with each other and to the actin-cytoskeleton.