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Homer 1b/c - 160 026

A post synaptic density (PSD) protein involved in the targeting of glutamate receptors
Polyclonal chicken IgY fraction
Cat. No.: 160 026
Amount: 200 µl
Price: $350.00
Cat. No. 160 026 200 µl antibody, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 500 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 176 to 354 from human Homer1b/c (UniProt Id: Q86YM7-1)
Reactivity Reacts with: mouse (Q9Z2Y3-3, Q9Z2Y3-2), rat (Q9Z214-2, Q9Z214-1), human (Q86YM7-1, Q86YM7-2).
Other species not tested yet.
Specificity Specific for homer 1b and 1c; no cross-reactivity to homer 1a.
Data sheet 160_026.pdf
Cat. No.: 160 026
Quantity: 200 µl
Price: $350.00

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.