Cat. No.: 159 103
Amount: 50 µg
Price:
$375.00
|
|
|
| Cat. No. 159 103 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 256 to 270 from mouse Endophilin2 (UniProt Id: Q62419) |
| Reactivity |
Reacts with: mouse (Q62419), rat (O35964). Other species not tested yet. |
| Data sheet | 159_103.pdf |
|
|
Endophilins are SH3 domain proteins involved in endocytosis. Both, Endophilin 1 and 2 have been shown to play important roles in clathrin mediated synaptic vesicle recycling. They recruite and stabilize the polyphosphoinositide phosphatase synaptojanin at nerve terminals.
The divergent C-terminal tail of VgluT1 has been reported to be a binding partner of Endophilin A1.
In contrast to Endophilin 1 that shows a brain specific expression, Endophilin 2 is abundantly expressed in different tissues.