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Endophilin 2 - 159 103

An SH3 domain protein involved in clathrin mediated endocytosis
Polyclonal rabbit purified antibody
Cat. No.: 159 103
Amount: 50 µg
Price: 370.00 €
Cat. No. 159 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 AP staining gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 256 to 270 from mouse Endophilin2 (UniProt Id: Q62419)
Reactivity Reacts with: mouse (Q62419), rat (O35964).
Other species not tested yet.
Specificity Specific for Endophilin 2
Data sheet 159_103.pdf
Cat. No.: 159 103
Quantity: 50 µg
Price: 370.00 €
Background

Endophilins are SH3 domain proteins involved in endocytosis. Both, Endophilin 1 and 2 have been shown to play important roles in clathrin mediated synaptic vesicle recycling. They recruite and stabilize the polyphosphoinositide phosphatase synaptojanin at nerve terminals.

The divergent C-terminal tail of VgluT1 has been reported to be a binding partner of Endophilin A1.

In contrast to Endophilin 1 that shows a brain specific expression, Endophilin 2 is abundantly expressed in different tissues.