|Cat. No. 155 002||200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery
IP: not tested yet
ICC: not recommended (see remarks)
IHC: not recommended
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 279 to 297 from rat AP180 (UniProt Id: Q05140)|
Reacts with: human (O60641), rat (Q05140), mouse (Q61548), dog.
Other species not tested yet.
|Specificity||Specific for AP 180.|
|Matching control protein/peptide||155-0P|
ICC: The affinity-purified antibody (cat. no. 155 003) is recommended.
During neurotransmitter release synaptic vesicles fuse with the presynaptic plasma membrane. A whole protein machinery consisting of e.g. amphiphysin, clathrin, endophilin and synaptojanin is involved in the subsequent endocytotic recycling of the synaptic vesicles.
AP 180 also known as pp155, NP185, F1-20, and SNAP 91 is a clathrin binding phospho-protein and faciliates the formation of clathrin coats.