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Home > Products > 151 003

GRIP antibody - 151 003

GRIP is a post-synaptic multi-PDZ domain protein
Rabbit polyclonal purified antibody
Cat. No.: 151 003
Amount: 50 µg
Price: $460.00
Cat. No. 151 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 100 up to 1 : 1000 gallery  
IP: not tested yet
ICC: 1 : 100 gallery  
IHC: not tested yet
IHC-P: not tested yet

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Recombinant protein corresponding to AA 662 to 769 from rat GRIP (UniProt Id: P97879)
Reactivity Reacts with: human (Q9Y3R0), rat (P97879), mouse (Q925T6), hamster.
Other species not tested yet.
Specificity Recognizes GRIP 1 and GRIP 2.
Matching control protein/peptide 151-0P
Data sheet 151_003.pdf

References for GRIP - 151 003

Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice.
Curti L, Rizzi B, Mottarlini F, Bigagli E, Ilari A, Costa A, Sordi V, Ranieri G, Luceri C, Cannella N, Ubaldi M, et al.
Progress in neuro-psychopharmacology & biological psychiatry (2025) 136: 111174. 151 003 WB; tested species: mouse
Expression of synaptic proteins and development of dendritic spines in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa.
Sobierajski E, Czubay K, Schmidt MR, Wiedenski S, Rettschlag S, Beemelmans C, Beemelmans C, Wahle P
Brain structure & function (2025) 2302: 38. 151 003 WB; tested species: pig
Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats.
Targa G, Mottarlini F, Rizzi B, Leo D, Caffino L, Fumagalli F
Biomolecules (2023) 133: . 151 003 WB; tested species: rat
Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats.
Mottarlini F, Bottan G, Tarenzi B, Colciago A, Fumagalli F, Caffino L
Nutrients (2020) 1212: . 151 003 WB; tested species: rat
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, et al.
Science (New York, N.Y.) (2018) : . 151 003 WB; tested species: rat
Cat. No.: 151 003
Amount: 50 µg
Price: $460.00
Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice.
Curti L, Rizzi B, Mottarlini F, Bigagli E, Ilari A, Costa A, Sordi V, Ranieri G, Luceri C, Cannella N, Ubaldi M, et al.
Progress in neuro-psychopharmacology & biological psychiatry (2025) 136: 111174. 151 003 WB; tested species: mouse
Expression of synaptic proteins and development of dendritic spines in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa.
Sobierajski E, Czubay K, Schmidt MR, Wiedenski S, Rettschlag S, Beemelmans C, Beemelmans C, Wahle P
Brain structure & function (2025) 2302: 38. 151 003 WB; tested species: pig
Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats.
Targa G, Mottarlini F, Rizzi B, Leo D, Caffino L, Fumagalli F
Biomolecules (2023) 133: . 151 003 WB; tested species: rat
Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats.
Mottarlini F, Bottan G, Tarenzi B, Colciago A, Fumagalli F, Caffino L
Nutrients (2020) 1212: . 151 003 WB; tested species: rat
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, et al.
Science (New York, N.Y.) (2018) : . 151 003 WB; tested species: rat
WB
ICC
Background

The glutamate receptor interacting protein GRIP is a post-synaptic scaffolding protein consisting of seven PDZ domains. It has been shown to interact with a diverse array of proteins like several AMPA receptors, HAP1-A, liprin-α and LAR receptor protein tyrosine phosphatases (LAR-RPTPs).
GRIP is also involved in the synaptic targeting of AMPA receptors.
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