Home|||||||Technical Support|

VGLUT 2 - 135 404

Glutamate transporter in the membrane of synaptic vesicles
Polyclonal Guinea pig antiserum
Cat. No.: 135 404
Amount: 100 µl
Price: $375.00
Cat. No. 135 404 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: yes
ICC: 1 : 200 up to 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
EM: yes
Immunogen Synthetic peptide corresponding to AA 566 to 582 from rat VGLUT2 (UniProt Id: Q9JI12)
Reactivity Reacts with: rat (Q9JI12), mouse (Q8BLE7).
Other species not tested yet.
Specificity Specific for VGLUT 2. K.O. PubMed: 25357191
Remarks

This antibody is highly recommended as a marker for glutamatergic nerve terminals.
WB: VGLUT 2 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

Data sheet 135_404.pdf

References for VGLUT 2 - 135 404

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 404 WB, ICC; tested species: human,mouse
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ, et al.
The EMBO journal (2020) : e103358. 135 404 WB; tested species: mouse
VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.
Richter K, Schmutz I, Darna M, Zander JF, Chavan R, Albrecht U, Ahnert-Hilger G
Neuroscience (2018) 371: 29-37. 135 404 WB; tested species: mouse
A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes.
Wolfes AC, Ahmed S, Awasthi A, Stahlberg MA, Rajput A, Magruder DS, Bonn S, Dean C
The Journal of general physiology (2017) 1491: 149-170. 135 404 WB
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm S, Antolin-Fontes B, Görlich A, Zander JF, Ahnert-Hilger G, Ibañez-Tallon I
eLife (2015) 4: e11396. 135 404 WB, IHC
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 404 WB, ICC; tested species: human,mouse
Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output.
Paraskevopoulou F, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3923: 4448-4460. 135 404 ICC; tested species: mouse
The Role of Agrin, Lrp4 and MuSK during Dendritic Arborization and Synaptogenesis in Cultured Embryonic CNS Neurons.
Handara G, Hetsch FJA, Jüttner R, Schick A, Haupt C, Rathjen FG, Kröger S
Developmental biology (2018) : . 135 404 ICC; tested species: mouse
Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury.
Casanovas A, Salvany S, Lahoz V, Tarabal O, Piedrafita L, Sabater R, Hernández S, Calderó J, Esquerda JE
Scientific reports (2017) 7: 40155. 135 404 ICC
Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture.
Herman MA, Ackermann F, Trimbuch T, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3435: 11781-91. 135 404 ICC; tested species: mouse
Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.
Weston MC, Chen H, Swann JW
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3233: 11441-52. 135 404 ICC; tested species: mouse
Splice-specific roles of glycine receptor alpha3 in the hippocampus.
Eichler SA, Förstera B, Smolinsky B, Jüttner R, Lehmann TN, Fähling M, Schwarz G, Legendre P, Meier JC
The European journal of neuroscience (2009) 306: 1077-91. 135 404 ICC, IHC; tested species: mouse
Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice.
Achilly NP, He LJ, Kim OA, Ohmae S, Wojaczynski GJ, Lin T, Sillitoe RV, Medina JF, Zoghbi HY
eLife (2021) 10: . 135 404 IHC; tested species: mouse
Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons.
Bourojeni FB, Zeilhofer HU, Kania A
Pain (2021) 1621: 161-175. 135 404 IHC; tested species: mouse
Structural basis for noradrenergic regulation of neural circuits in the mouse olfactory bulb.
Horie S, Kiyokage E, Hayashi S, Inoue K, Sohn J, Hioki H, Furuta T, Toida K
The Journal of comparative neurology (2020) : . 135 404 IHC; tested species: mouse
Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum.
Katona L, Hartwich K, Tomioka R, Somogyi J, Roberts JDB, Wagner K, Joshi A, Klausberger T, Rockland KS, Somogyi P
Brain structure & function (2020) 2252: 705-734. 135 404 IHC; tested species: mouse,rat
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Linker KE, Elabd MG, Tawadrous P, Cano M, Green KN, Wood MA, Leslie FM
Nature communications (2020) 111: 306. 135 404 IHC; tested species: rat
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities.
Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, et al.
Molecular psychiatry (2020) : . 135 404 IHC; tested species: mouse
The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex.
Nestvogel DB, Merino RM, Leon-Pinzon C, Schottdorf M, Lee C, Imig C, Brose N, Rhee JS
Cell reports (2020) 3010: 3261-3269.e4. 135 404 IHC; tested species: mouse
High-fat diet induces time-dependent synaptic plasticity of the lateral hypothalamus.
Linehan V, Fang LZ, Parsons MP, Hirasawa M
Molecular metabolism (2020) : 100977. 135 404 IHC; tested species: rat
Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis.
Soulard C, Salsac C, Mouzat K, Hilaire C, Roussel J, Mezghrani A, Lumbroso S, Raoul C, Scamps F
Cell reports (2020) 308: 2581-2593.e7. 135 404 IHC; tested species: mouse
The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development.
Cong Q, Soteros BM, Wollet M, Kim JH, Sia GM
Nature neuroscience (2020) : . 135 404 IHC; tested species: mouse
SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Sauerbeck AD, Gangolli M, Reitz SJ, Salyards MH, Kim SH, Hemingway C, Gratuze M, Makkapati T, Kerschensteiner M, Holtzman DM, Brody DL, et al.
Neuron (2020) 1072: 257-273.e5. 135 404 IHC; tested species: mouse
Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling.
Han KS, Chen CH, Khan MM, Guo C, Regehr WG
Nature neuroscience (2020) : . 135 404 IHC; tested species: mouse
Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.
Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, et al.
Cell reports (2020) 338: 108425. 135 404 IHC; tested species: mouse
Loss of Piccolo Function in Rats Induces Cerebellar Network Dysfunction and Pontocerebellar Hypoplasia Type 3-like Phenotypes.
Falck J, Bruns C, Hoffmann-Conaway S, Straub I, Plautz EJ, Orlando M, Munawar H, Rivalan M, Winter Y, Izsvák Z, Schmitz D, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) 4014: 2943-2959. 135 404 IHC; tested species: rat
Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice.
Blasco A, Gras S, Mòdol-Caballero G, Tarabal O, Casanovas A, Piedrafita L, Barranco A, Das T, Pereira SL, Navarro X, Rueda R, et al.
Journal of cachexia, sarcopenia and muscle (2020) : . 135 404 IHC; tested species: mouse
Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons.
Petitjean H, B Bourojeni F, Tsao D, Davidova A, Sotocinal SG, Mogil JS, Kania A, Sharif-Naeini R
Cell reports (2019) 286: 1429-1438.e4. 135 404 IHC; tested species: mouse
Cholinergic neurons of the medial septum are crucial for sensorimotor gating.
Jin J, Cheng J, Lee KW, Amreen B, McCabe K, Pitcher C, Liebmann T, Greengard P, Flajolet M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 135 404 IHC; tested species: mouse
Quantitative organization of the excitatory synapses of the primate cerebellar nuclei: further evidence for a specialized architecture underlying the primate cerebellum.
Mao H, Hamodeh S, Skodras A, Sultan F
Brain structure & function (2019) : . 135 404 IHC; tested species: monkey
Endogenous Glutamate Excites Myenteric Calbindin Neurons by Activating Group I Metabotropic Glutamate Receptors in the Mouse Colon.
Swaminathan M, Hill-Yardin EL, Bornstein JC, Foong JPP
Frontiers in neuroscience (2019) 13: 426. 135 404 IHC; tested species: mouse
Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior.
Inoue S, Yang R, Tantry A, Davis CH, Yang T, Knoedler JR, Wei Y, Adams EL, Thombare S, Golf SR, Neve RL, et al.
Cell (2019) : . 135 404 IHC; tested species: mouse
Structural and functional connections between the median and the ventrolateral preoptic nucleus.
Walter A, van der Spek L, Hardy E, Bemelmans AP, Rouach N, Rancillac A
Brain structure & function (2019) : . 135 404 IHC; tested species: mouse
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz C, Ruffault PL, Chéret C, Woehler A, Zampieri N, Fortin G, Garratt AN, Birchmeier C
Development (Cambridge, England) (2019) 14617: . 135 404 IHC; tested species: mouse
VGluT1 Deficiency Impairs Visual Attention and Reduces the Dynamic Range of Short-Term Plasticity at Corticothalamic Synapses.
Lindström SH, Sundberg SC, Larsson M, Andersson FK, Broman J, Granseth B
Cerebral cortex (New York, N.Y. : 1991) (2019) : . 135 404 IHC; tested species: mouse
From back to front: A functional model for the cerebellar modulation in the establishment of conditioned preferences for cocaine-related cues.
Gil-Miravet I, Melchor-Eixea I, Arias-Sandoval E, Vasquez-Celaya L, Guarque-Chabrera J, Olucha-Bordonau F, Miquel M
Addiction biology (2019) : e12834. 135 404 IHC; tested species: rat
Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release.
Turecek J, Regehr WG
Neuron (2019) : . 135 404 IHC; tested species: mouse
The development of synaptic transmission is time-locked to early social behaviors in rats.
Naskar S, Narducci R, Balzani E, Cwetsch AW, Tucci V, Cancedda L
Nature communications (2019) 101: 1195. 135 404 IHC; tested species: rat
Pathological changes of distal motor neurons after complete spinal cord injury.
Yokota K, Kubota K, Kobayakawa K, Saito T, Hara M, Kijima K, Maeda T, Katoh H, Ohkawa Y, Nakashima Y, Okada S, et al.
Molecular brain (2019) 121: 4. 135 404 IHC; tested species: mouse
A characterization of laminar architecture in mouse primary auditory cortex.
Chang M, Kawai HD
Brain structure & function (2018) : . 135 404 IHC; tested species: mouse
Laminar specific gene expression reveals differences in postnatal laminar maturation in mouse auditory, visual, and somatosensory cortex.
Chang M, Suzuki N, Kawai HD
The Journal of comparative neurology (2018) : . 135 404 IHC; tested species: mouse
Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum.
Viney TJ, Salib M, Joshi A, Unal G, Berry N, Somogyi P
eLife (2018) 7: . 135 404 IHC; tested species: mouse
Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.
Alpár A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, et al.
The EMBO journal (2018) : . 135 404 IHC; tested species: mouse
G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons.
Katidou M, Grosmaitre X, Lin J, Mombaerts P
Molecular and cellular neurosciences (2018) 88: 138-147. 135 404 IHC; tested species: mouse
Quantitative Comparison Of Vesicular Glutamate Transporters in rat Deep Cerebellar Nuclei.
Mao H, Hamodeh S, Sultan F
Neuroscience (2018) 376: 152-161. 135 404 IHC; tested species: rat
VGLUT1 or VGLUT2 mRNA-positive neurons in spinal trigeminal nucleus provide collateral projections to both the thalamus and the parabrachial nucleus in rats.
Zhang CK, Li ZH, Qiao Y, Zhang T, Lu YC, Chen T, Dong YL, Li YQ, Li JL
Molecular brain (2018) 111: 22. 135 404 IHC; tested species: rat
VIP-immunoreactive interneurons within circuits of the mouse basolateral amygdala.
Rhomberg T, Rovira-Esteban L, Vikór A, Paradiso E, Kremser C, Nagy-Pál P, Papp OI, Tasan R, Erdélyi F, Szabó G, Ferraguti F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 135 404 IHC; tested species: mouse
Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex.
Oda S, Tsuneoka Y, Yoshida S, Adachi-Akahane S, Ito M, Kuroda M, Funato H
The Journal of comparative neurology (2018) 5268: 1329-1350. 135 404 IHC; tested species: rat
Specific synaptic input strengths determine the computational properties of excitation - inhibition integration in a sound localization circuit.
Gjoni E, Zenke F, Bouhours B, Schneggenburger R
The Journal of physiology (2018) : . 135 404 IHC; tested species: mouse
Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.
Risher WC, Kim N, Koh S, Choi JE, Mitev P, Spence EF, Pilaz LJ, Wang D, Feng G, Silver DL, Soderling SH, et al.
The Journal of cell biology (2018) : . 135 404 IHC; tested species: mouse
Regulation of striatal cells and goal-directed behavior by cerebellar outputs.
Xiao L, Bornmann C, Hatstatt-Burklé L, Scheiffele P
Nature communications (2018) 91: 3133. 135 404 IHC; tested species: mouse
Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons.
Edamatsu M, Miyano R, Fujikawa A, Fujii F, Hori T, Sakaba T, Oohashi T
Journal of neurochemistry (2018) : . 135 404 IHC; tested species: mouse
The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization.
Laperchia C, Imperatore R, Azeez IA, Del Gallo F, Bertini G, Grassi-Zucconi G, Cristino L, Bentivoglio M
Brain structure & function (2017) 2228: 3847-3859. 135 404 IHC; tested species: mouse
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice.
Freria CM, Hall JC, Wei P, Guan Z, McTigue DM, Popovich PG
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3713: 3568-3587. 135 404 IHC; tested species: mouse
Behavior-Dependent Activity and Synaptic Organization of Septo-hippocampal GABAergic Neurons Selectively Targeting the Hippocampal CA3 Area.
Joshi A, Salib M, Viney TJ, Dupret D, Somogyi P
Neuron (2017) 966: 1342-1357.e5. 135 404 IHC
Role of primary afferents in the developmental regulation of motor axon synapse numbers on Renshaw cells.
Siembab VC, Gomez-Perez L, Rotterman TM, Shneider NA, Alvarez FJ
The Journal of comparative neurology (2016) 5249: 1892-919. 135 404 IHC; tested species: mouse
Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity.
Etxeberria A, Hokanson KC, Dao DQ, Mayoral SR, Mei F, Redmond SA, Ullian EM, Chan JR
The Journal of neuroscience : the official journal of the Society for Neuroscience (2016) 3626: 6937-48. 135 404 IHC; KO verified; tested species: mouse
Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.
Heise C, Schroeder JC, Schoen M, Halbedl S, Reim D, Woelfle S, Kreutz MR, Schmeisser MJ, Boeckers TM
Frontiers in cellular neuroscience (2016) 10: 106. 135 404 IHC
Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse.
Faralli A, Dagna F, Albera A, Bekku Y, Oohashi T, Albera R, Rossi F, Carulli D
Brain structure & function (2016) 2216: 3193-209. 135 404 IHC
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm S, Antolin-Fontes B, Görlich A, Zander JF, Ahnert-Hilger G, Ibañez-Tallon I
eLife (2015) 4: e11396. 135 404 WB, IHC
Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates.
Broms J, Antolin-Fontes B, Tingström A, Ibañez-Tallon I
The Journal of comparative neurology (2015) 5233: 359-80. 135 404 IHC
Astrocytes refine cortical connectivity at dendritic spines.
Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz LJ, Singh Alvarado J, Calhan OY, Silver DL, Stevens B, et al.
eLife (2014) 3: . 135 404 IHC
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
Li KW, Yu YP, Zhou C, Kim DS, Lin B, Sharp K, Steward O, Luo ZD
The Journal of biological chemistry (2014) 28910: 7025-37. 135 404 IHC; tested species: rat
Mice deficient of glutamatergic signaling from intrinsically photosensitive retinal ganglion cells exhibit abnormal circadian photoentrainment.
Purrier N, Engeland WC, Kofuji P
PloS one (2014) 910: e111449. 135 404 IHC; KO verified; tested species: mouse
Characterization of long descending premotor propriospinal neurons in the spinal cord.
Ni Y, Nawabi H, Liu X, Yang L, Miyamichi K, Tedeschi A, Xu B, Wall NR, Callaway EM, He Z
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3428: 9404-17. 135 404 IHC; tested species: mouse
Neural injury alters proliferation and integration of adult-generated neurons in the dentate gyrus.
Perederiy JV, Luikart BW, Washburn EK, Schnell E, Westbrook GL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3311: 4754-67. 135 404 IHC
Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina.
Michalski D, Härtig W, Krügel K, Edwards RH, Böddener M, Böhme L, Pannicke T, Reichenbach A, Grosche A
Neuroscience (2013) 231: 328-44. 135 404 IHC
Somatostatin varicosities contain the vesicular GABA transporter and contact orexin neurons in the hypothalamus.
Toossi H, Del Cid-Pellitero E, Stroh T, Jones BE
The European journal of neuroscience (2012) 3610: 3388-95. 135 404 IHC
Splice-specific roles of glycine receptor alpha3 in the hippocampus.
Eichler SA, Förstera B, Smolinsky B, Jüttner R, Lehmann TN, Fähling M, Schwarz G, Legendre P, Meier JC
The European journal of neuroscience (2009) 306: 1077-91. 135 404 ICC, IHC; tested species: mouse
Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats.
Hitchcock IS, Genever PG, Cahusac PM
Neuroscience letters (2004) 3623: 196-9. 135 404 IHC; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 135 404 IHC; tested species: rat
Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning.
Mills F, Globa AK, Liu S, Cowan CM, Mobasser M, Phillips AG, Borgland SL, Bamji SX
Nature neuroscience (2017) 204: 540-549. 135 404 EM; tested species: mouse
Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to α-motoneurons and altered during motoneuron diseases.
Gallart-Palau X, Tarabal O, Casanovas A, Sábado J, Correa FJ, Hereu M, Piedrafita L, Calderó J, Esquerda JE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2014) 288: 3618-32. 135 404 ; tested species: mouse
Cat. No.: 135 404
Quantity: 100 µl
Price: $375.00
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 404 WB, ICC; tested species: human,mouse
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ, et al.
The EMBO journal (2020) : e103358. 135 404 WB; tested species: mouse
VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.
Richter K, Schmutz I, Darna M, Zander JF, Chavan R, Albrecht U, Ahnert-Hilger G
Neuroscience (2018) 371: 29-37. 135 404 WB; tested species: mouse
A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes.
Wolfes AC, Ahmed S, Awasthi A, Stahlberg MA, Rajput A, Magruder DS, Bonn S, Dean C
The Journal of general physiology (2017) 1491: 149-170. 135 404 WB
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm S, Antolin-Fontes B, Görlich A, Zander JF, Ahnert-Hilger G, Ibañez-Tallon I
eLife (2015) 4: e11396. 135 404 WB, IHC
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 404 WB, ICC; tested species: human,mouse
Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output.
Paraskevopoulou F, Herman MA, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) 3923: 4448-4460. 135 404 ICC; tested species: mouse
The Role of Agrin, Lrp4 and MuSK during Dendritic Arborization and Synaptogenesis in Cultured Embryonic CNS Neurons.
Handara G, Hetsch FJA, Jüttner R, Schick A, Haupt C, Rathjen FG, Kröger S
Developmental biology (2018) : . 135 404 ICC; tested species: mouse
Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury.
Casanovas A, Salvany S, Lahoz V, Tarabal O, Piedrafita L, Sabater R, Hernández S, Calderó J, Esquerda JE
Scientific reports (2017) 7: 40155. 135 404 ICC
Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture.
Herman MA, Ackermann F, Trimbuch T, Rosenmund C
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3435: 11781-91. 135 404 ICC; tested species: mouse
Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.
Weston MC, Chen H, Swann JW
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3233: 11441-52. 135 404 ICC; tested species: mouse
Splice-specific roles of glycine receptor alpha3 in the hippocampus.
Eichler SA, Förstera B, Smolinsky B, Jüttner R, Lehmann TN, Fähling M, Schwarz G, Legendre P, Meier JC
The European journal of neuroscience (2009) 306: 1077-91. 135 404 ICC, IHC; tested species: mouse
Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice.
Achilly NP, He LJ, Kim OA, Ohmae S, Wojaczynski GJ, Lin T, Sillitoe RV, Medina JF, Zoghbi HY
eLife (2021) 10: . 135 404 IHC; tested species: mouse
Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons.
Bourojeni FB, Zeilhofer HU, Kania A
Pain (2021) 1621: 161-175. 135 404 IHC; tested species: mouse
Structural basis for noradrenergic regulation of neural circuits in the mouse olfactory bulb.
Horie S, Kiyokage E, Hayashi S, Inoue K, Sohn J, Hioki H, Furuta T, Toida K
The Journal of comparative neurology (2020) : . 135 404 IHC; tested species: mouse
Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum.
Katona L, Hartwich K, Tomioka R, Somogyi J, Roberts JDB, Wagner K, Joshi A, Klausberger T, Rockland KS, Somogyi P
Brain structure & function (2020) 2252: 705-734. 135 404 IHC; tested species: mouse,rat
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Linker KE, Elabd MG, Tawadrous P, Cano M, Green KN, Wood MA, Leslie FM
Nature communications (2020) 111: 306. 135 404 IHC; tested species: rat
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities.
Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, et al.
Molecular psychiatry (2020) : . 135 404 IHC; tested species: mouse
The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex.
Nestvogel DB, Merino RM, Leon-Pinzon C, Schottdorf M, Lee C, Imig C, Brose N, Rhee JS
Cell reports (2020) 3010: 3261-3269.e4. 135 404 IHC; tested species: mouse
High-fat diet induces time-dependent synaptic plasticity of the lateral hypothalamus.
Linehan V, Fang LZ, Parsons MP, Hirasawa M
Molecular metabolism (2020) : 100977. 135 404 IHC; tested species: rat
Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis.
Soulard C, Salsac C, Mouzat K, Hilaire C, Roussel J, Mezghrani A, Lumbroso S, Raoul C, Scamps F
Cell reports (2020) 308: 2581-2593.e7. 135 404 IHC; tested species: mouse
The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development.
Cong Q, Soteros BM, Wollet M, Kim JH, Sia GM
Nature neuroscience (2020) : . 135 404 IHC; tested species: mouse
SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Sauerbeck AD, Gangolli M, Reitz SJ, Salyards MH, Kim SH, Hemingway C, Gratuze M, Makkapati T, Kerschensteiner M, Holtzman DM, Brody DL, et al.
Neuron (2020) 1072: 257-273.e5. 135 404 IHC; tested species: mouse
Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling.
Han KS, Chen CH, Khan MM, Guo C, Regehr WG
Nature neuroscience (2020) : . 135 404 IHC; tested species: mouse
Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.
Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, et al.
Cell reports (2020) 338: 108425. 135 404 IHC; tested species: mouse
Loss of Piccolo Function in Rats Induces Cerebellar Network Dysfunction and Pontocerebellar Hypoplasia Type 3-like Phenotypes.
Falck J, Bruns C, Hoffmann-Conaway S, Straub I, Plautz EJ, Orlando M, Munawar H, Rivalan M, Winter Y, Izsvák Z, Schmitz D, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) 4014: 2943-2959. 135 404 IHC; tested species: rat
Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice.
Blasco A, Gras S, Mòdol-Caballero G, Tarabal O, Casanovas A, Piedrafita L, Barranco A, Das T, Pereira SL, Navarro X, Rueda R, et al.
Journal of cachexia, sarcopenia and muscle (2020) : . 135 404 IHC; tested species: mouse
Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons.
Petitjean H, B Bourojeni F, Tsao D, Davidova A, Sotocinal SG, Mogil JS, Kania A, Sharif-Naeini R
Cell reports (2019) 286: 1429-1438.e4. 135 404 IHC; tested species: mouse
Cholinergic neurons of the medial septum are crucial for sensorimotor gating.
Jin J, Cheng J, Lee KW, Amreen B, McCabe K, Pitcher C, Liebmann T, Greengard P, Flajolet M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 135 404 IHC; tested species: mouse
Quantitative organization of the excitatory synapses of the primate cerebellar nuclei: further evidence for a specialized architecture underlying the primate cerebellum.
Mao H, Hamodeh S, Skodras A, Sultan F
Brain structure & function (2019) : . 135 404 IHC; tested species: monkey
Endogenous Glutamate Excites Myenteric Calbindin Neurons by Activating Group I Metabotropic Glutamate Receptors in the Mouse Colon.
Swaminathan M, Hill-Yardin EL, Bornstein JC, Foong JPP
Frontiers in neuroscience (2019) 13: 426. 135 404 IHC; tested species: mouse
Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior.
Inoue S, Yang R, Tantry A, Davis CH, Yang T, Knoedler JR, Wei Y, Adams EL, Thombare S, Golf SR, Neve RL, et al.
Cell (2019) : . 135 404 IHC; tested species: mouse
Structural and functional connections between the median and the ventrolateral preoptic nucleus.
Walter A, van der Spek L, Hardy E, Bemelmans AP, Rouach N, Rancillac A
Brain structure & function (2019) : . 135 404 IHC; tested species: mouse
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz C, Ruffault PL, Chéret C, Woehler A, Zampieri N, Fortin G, Garratt AN, Birchmeier C
Development (Cambridge, England) (2019) 14617: . 135 404 IHC; tested species: mouse
VGluT1 Deficiency Impairs Visual Attention and Reduces the Dynamic Range of Short-Term Plasticity at Corticothalamic Synapses.
Lindström SH, Sundberg SC, Larsson M, Andersson FK, Broman J, Granseth B
Cerebral cortex (New York, N.Y. : 1991) (2019) : . 135 404 IHC; tested species: mouse
From back to front: A functional model for the cerebellar modulation in the establishment of conditioned preferences for cocaine-related cues.
Gil-Miravet I, Melchor-Eixea I, Arias-Sandoval E, Vasquez-Celaya L, Guarque-Chabrera J, Olucha-Bordonau F, Miquel M
Addiction biology (2019) : e12834. 135 404 IHC; tested species: rat
Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release.
Turecek J, Regehr WG
Neuron (2019) : . 135 404 IHC; tested species: mouse
The development of synaptic transmission is time-locked to early social behaviors in rats.
Naskar S, Narducci R, Balzani E, Cwetsch AW, Tucci V, Cancedda L
Nature communications (2019) 101: 1195. 135 404 IHC; tested species: rat
Pathological changes of distal motor neurons after complete spinal cord injury.
Yokota K, Kubota K, Kobayakawa K, Saito T, Hara M, Kijima K, Maeda T, Katoh H, Ohkawa Y, Nakashima Y, Okada S, et al.
Molecular brain (2019) 121: 4. 135 404 IHC; tested species: mouse
A characterization of laminar architecture in mouse primary auditory cortex.
Chang M, Kawai HD
Brain structure & function (2018) : . 135 404 IHC; tested species: mouse
Laminar specific gene expression reveals differences in postnatal laminar maturation in mouse auditory, visual, and somatosensory cortex.
Chang M, Suzuki N, Kawai HD
The Journal of comparative neurology (2018) : . 135 404 IHC; tested species: mouse
Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum.
Viney TJ, Salib M, Joshi A, Unal G, Berry N, Somogyi P
eLife (2018) 7: . 135 404 IHC; tested species: mouse
Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.
Alpár A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, et al.
The EMBO journal (2018) : . 135 404 IHC; tested species: mouse
G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons.
Katidou M, Grosmaitre X, Lin J, Mombaerts P
Molecular and cellular neurosciences (2018) 88: 138-147. 135 404 IHC; tested species: mouse
Quantitative Comparison Of Vesicular Glutamate Transporters in rat Deep Cerebellar Nuclei.
Mao H, Hamodeh S, Sultan F
Neuroscience (2018) 376: 152-161. 135 404 IHC; tested species: rat
VGLUT1 or VGLUT2 mRNA-positive neurons in spinal trigeminal nucleus provide collateral projections to both the thalamus and the parabrachial nucleus in rats.
Zhang CK, Li ZH, Qiao Y, Zhang T, Lu YC, Chen T, Dong YL, Li YQ, Li JL
Molecular brain (2018) 111: 22. 135 404 IHC; tested species: rat
VIP-immunoreactive interneurons within circuits of the mouse basolateral amygdala.
Rhomberg T, Rovira-Esteban L, Vikór A, Paradiso E, Kremser C, Nagy-Pál P, Papp OI, Tasan R, Erdélyi F, Szabó G, Ferraguti F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 135 404 IHC; tested species: mouse
Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex.
Oda S, Tsuneoka Y, Yoshida S, Adachi-Akahane S, Ito M, Kuroda M, Funato H
The Journal of comparative neurology (2018) 5268: 1329-1350. 135 404 IHC; tested species: rat
Specific synaptic input strengths determine the computational properties of excitation - inhibition integration in a sound localization circuit.
Gjoni E, Zenke F, Bouhours B, Schneggenburger R
The Journal of physiology (2018) : . 135 404 IHC; tested species: mouse
Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.
Risher WC, Kim N, Koh S, Choi JE, Mitev P, Spence EF, Pilaz LJ, Wang D, Feng G, Silver DL, Soderling SH, et al.
The Journal of cell biology (2018) : . 135 404 IHC; tested species: mouse
Regulation of striatal cells and goal-directed behavior by cerebellar outputs.
Xiao L, Bornmann C, Hatstatt-Burklé L, Scheiffele P
Nature communications (2018) 91: 3133. 135 404 IHC; tested species: mouse
Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons.
Edamatsu M, Miyano R, Fujikawa A, Fujii F, Hori T, Sakaba T, Oohashi T
Journal of neurochemistry (2018) : . 135 404 IHC; tested species: mouse
The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization.
Laperchia C, Imperatore R, Azeez IA, Del Gallo F, Bertini G, Grassi-Zucconi G, Cristino L, Bentivoglio M
Brain structure & function (2017) 2228: 3847-3859. 135 404 IHC; tested species: mouse
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice.
Freria CM, Hall JC, Wei P, Guan Z, McTigue DM, Popovich PG
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3713: 3568-3587. 135 404 IHC; tested species: mouse
Behavior-Dependent Activity and Synaptic Organization of Septo-hippocampal GABAergic Neurons Selectively Targeting the Hippocampal CA3 Area.
Joshi A, Salib M, Viney TJ, Dupret D, Somogyi P
Neuron (2017) 966: 1342-1357.e5. 135 404 IHC
Role of primary afferents in the developmental regulation of motor axon synapse numbers on Renshaw cells.
Siembab VC, Gomez-Perez L, Rotterman TM, Shneider NA, Alvarez FJ
The Journal of comparative neurology (2016) 5249: 1892-919. 135 404 IHC; tested species: mouse
Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity.
Etxeberria A, Hokanson KC, Dao DQ, Mayoral SR, Mei F, Redmond SA, Ullian EM, Chan JR
The Journal of neuroscience : the official journal of the Society for Neuroscience (2016) 3626: 6937-48. 135 404 IHC; KO verified; tested species: mouse
Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.
Heise C, Schroeder JC, Schoen M, Halbedl S, Reim D, Woelfle S, Kreutz MR, Schmeisser MJ, Boeckers TM
Frontiers in cellular neuroscience (2016) 10: 106. 135 404 IHC
Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse.
Faralli A, Dagna F, Albera A, Bekku Y, Oohashi T, Albera R, Rossi F, Carulli D
Brain structure & function (2016) 2216: 3193-209. 135 404 IHC
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm S, Antolin-Fontes B, Görlich A, Zander JF, Ahnert-Hilger G, Ibañez-Tallon I
eLife (2015) 4: e11396. 135 404 WB, IHC
Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates.
Broms J, Antolin-Fontes B, Tingström A, Ibañez-Tallon I
The Journal of comparative neurology (2015) 5233: 359-80. 135 404 IHC
Astrocytes refine cortical connectivity at dendritic spines.
Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz LJ, Singh Alvarado J, Calhan OY, Silver DL, Stevens B, et al.
eLife (2014) 3: . 135 404 IHC
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
Li KW, Yu YP, Zhou C, Kim DS, Lin B, Sharp K, Steward O, Luo ZD
The Journal of biological chemistry (2014) 28910: 7025-37. 135 404 IHC; tested species: rat
Mice deficient of glutamatergic signaling from intrinsically photosensitive retinal ganglion cells exhibit abnormal circadian photoentrainment.
Purrier N, Engeland WC, Kofuji P
PloS one (2014) 910: e111449. 135 404 IHC; KO verified; tested species: mouse
Characterization of long descending premotor propriospinal neurons in the spinal cord.
Ni Y, Nawabi H, Liu X, Yang L, Miyamichi K, Tedeschi A, Xu B, Wall NR, Callaway EM, He Z
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3428: 9404-17. 135 404 IHC; tested species: mouse
Neural injury alters proliferation and integration of adult-generated neurons in the dentate gyrus.
Perederiy JV, Luikart BW, Washburn EK, Schnell E, Westbrook GL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3311: 4754-67. 135 404 IHC
Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina.
Michalski D, Härtig W, Krügel K, Edwards RH, Böddener M, Böhme L, Pannicke T, Reichenbach A, Grosche A
Neuroscience (2013) 231: 328-44. 135 404 IHC
Somatostatin varicosities contain the vesicular GABA transporter and contact orexin neurons in the hypothalamus.
Toossi H, Del Cid-Pellitero E, Stroh T, Jones BE
The European journal of neuroscience (2012) 3610: 3388-95. 135 404 IHC
Splice-specific roles of glycine receptor alpha3 in the hippocampus.
Eichler SA, Förstera B, Smolinsky B, Jüttner R, Lehmann TN, Fähling M, Schwarz G, Legendre P, Meier JC
The European journal of neuroscience (2009) 306: 1077-91. 135 404 ICC, IHC; tested species: mouse
Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats.
Hitchcock IS, Genever PG, Cahusac PM
Neuroscience letters (2004) 3623: 196-9. 135 404 IHC; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 135 404 IHC; tested species: rat
Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning.
Mills F, Globa AK, Liu S, Cowan CM, Mobasser M, Phillips AG, Borgland SL, Bamji SX
Nature neuroscience (2017) 204: 540-549. 135 404 EM; tested species: mouse
Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to α-motoneurons and altered during motoneuron diseases.
Gallart-Palau X, Tarabal O, Casanovas A, Sábado J, Correa FJ, Hereu M, Piedrafita L, Calderó J, Esquerda JE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2014) 288: 3618-32. 135 404 ; tested species: mouse
Background

The vesicular glutamate transporter 2 VGLUT 2, also referred to as DNPI and SLC17A6, has a more restricted expression than the related VGLUT 1. Like VGLUT 1, it is both necessary and sufficient for uptake and storage of glutamate and thus comprises the sole determinant for a glutamatergic phenotype. Both VGLUTs are different from the plasma membrane transporters in that they are driven by a proton electrochemical gradient across the vesicle membrane.
VGLUT 1 and VGLUT 2 show complementary expression patterns. Together, they are currently the best markers for glutamatergic nerve terminals and glutamatergic synapses.