Cat. No.: 135 303C5
Amount: 50 µg
Price:
$475.00
| Cat. No. 135 303C5 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen, fluorescence-labeled with Oyster® 650
Fluorescence labeled antibodies conjugated to Oyster dyes from Oyster dyes, Oyster-488, Oyster-500, Oyster-550, and Oyster-650 are trademarks of Luminartis GmbH, Muenster/Germany. CyDyes, Cy2, Cy3, and Cy5 are trademarks of GE-Healthcare Ltd. Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.The mounting agent Aquatex®(Merck Chemicals) is not compatible with Oyster dyes! |
| Applications |
WB: N/A IP: N/A ICC: 1 : 500 up to 1 : 10000 gallery IHC: 1 : 500 up to 1 : 1000 gallery IHC-P/FFPE: not tested yet |
| Label | Oyster 650 |
| Immunogen | Recombinant protein corresponding to AA 456 to 560 from rat VGLUT1 (UniProt Id: Q62634) |
| Reactivity |
Reacts with: human (Q9P2U7), rat (Q62634), mouse (Q3TXX4), cow, goat, sheep, dog. Other species not tested yet. |
| Specificity | Specific for VGLUT 1. K.O. |
| Matching control protein/peptide | 135-3P |
| Remarks |
This antibody is highly recommended as markers for glutamatergic nerve terminals. |
| Data sheet | 135_303c5.pdf |
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The vesicular glutamate transporter 1 VGLUT 1, also referred to as BNPI and SLC17A7, was originally identified as a brain specific phosphate transporter. Like the related VGLUT 2, VGLUT 1 is both necessary and sufficient for uptake and storage of glutamate and thus comprises the sole determinant for a glutamatergic phenotype. Both VGLUTs are different from the plasma membrane transporters in that they are driven by a proton electrochemical gradient across the vesicle membrane.
VGLUT 1 and VGLUT 2 show complementary expression patterns. Together, they are currently the best markers for glutamatergic nerve terminals and glutamatergic synapses.
