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Home > Products > 135 203

VGLUT3 antibody - 135 203 K.O.

VGluT3 is a synaptic vesicle glutamate transporter
Rabbit polyclonal purified antibody
Cat. No.: 135 203
Amount: 50 µg
Price: $400.00
Cat. No. 135 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: yes
IHC: 1 : 100 up to 1 : 1000 gallery  
IHC-P: 1 : 200 gallery  
FACS: yes

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.

Fluorescence-activated cell sorting (FACS); usually cells are fluorescently labeled with antibodies against cell-surface antigens followed by cell-sorter analysis.
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of mouse VGLUT 3 (UniProt Id: Q8BFU8)
Reactivity Reacts with: rat (Q7TSF2), mouse (Q8BFU8).
No signal: human.
Other species not tested yet.
Specificity K.O. validated PubMed: 21297271
Matching control protein/peptide 135-2P
Remarks

WB: Due to the low abundance of this protein in the brain, immunoblotting is difficult.
Data sheet 135_203.pdf

References for VGLUT3 - 135 203

Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia.
Tassone A, Martella G, Meringolo M, Vanni V, Sciamanna G, Ponterio G, Imbriani P, Bonsi P, Pisani A
Movement disorders : official journal of the Movement Disorder Society (2021) : . 135 203 WB; tested species: mouse
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 203 WB, ICC; tested species: human,mouse
Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells.
Sánchez-Mendoza EH, Bellver-Landete V, Arce C, Doeppner TR, Hermann DM, Oset-Gasque MJ
PloS one (2017) 125: e0177069. 135 203 WB, ICC
A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes.
Wolfes AC, Ahmed S, Awasthi A, Stahlberg MA, Rajput A, Magruder DS, Bonn S, Dean C
The Journal of general physiology (2017) 1491: 149-170. 135 203 WB
Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.
Li D, Hérault K, Silm K, Evrard A, Wojcik S, Oheim M, Herzog E, Ropert N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3310: 4434-55. 135 203 WB, IHC; KO verified; tested species: mouse
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.
Schallier A, Smolders I, Van Dam D, Loyens E, De Deyn PP, Michotte A, Michotte Y, Massie A
Journal of Alzheimer's disease : JAD (2011) 242: 287-300. 135 203 WB, IHC; KO verified; tested species: mouse
Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.
De Bundel D, Schallier A, Loyens E, Fernando R, Miyashita H, Van Liefferinge J, Vermoesen K, Bannai S, Sato H, Michotte Y, Smolders I, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5792-803. 135 203 WB; tested species: mouse
Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia.
Sánchez-Mendoza E, Burguete MC, Castelló-Ruiz M, González MP, Roncero C, Salom JB, Arce C, Cañadas S, Torregrosa G, Alborch E, Oset-Gasque MJ, et al.
Journal of neurochemistry (2010) 1135: 1343-55. 135 203 IHC, WB; tested species: rat
An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size.
Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N, Rosenmund C
Proceedings of the National Academy of Sciences of the United States of America (2004) 10118: 7158-63. 135 203 WB; tested species: mouse
The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, Zimmermann J, Henrion A, Mansouri-Guilani N, Mounier C, Ribeiro S, et al.
Nature communications (2024) 151: 5691. 135 203 ICC, IHC; tested species: mouse
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model.
Rickner HD, Jiang L, Hong R, O'Neill NK, Mojica CA, Snyder BJ, Zhang L, Shaw D, Medalla M, Wolozin B, Cheng CS, et al.
Nature communications (2022) 131: 6275. 135 203 ICC; tested species: human
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 203 WB, ICC; tested species: human,mouse
Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells.
Sánchez-Mendoza EH, Bellver-Landete V, Arce C, Doeppner TR, Hermann DM, Oset-Gasque MJ
PloS one (2017) 125: e0177069. 135 203 WB, ICC
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice.
Herzog E, Nadrigny F, Silm K, Biesemann C, Helling I, Bersot T, Steffens H, Schwartzmann R, Nägerl UV, El Mestikawy S, Rhee J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3143: 15544-59. 135 203 ICC; tested species: mouse
A hybridization-chain-reaction-based method for amplifying immunosignals.
Lin R, Feng Q, Li P, Zhou P, Wang R, Liu Z, Wang Z, Qi X, Tang N, Shao F, Luo M, et al.
Nature methods (2018) 154: 275-278. 135 203 IHC; tested species: mouse
Feedforward inhibition of stress by brainstem neuropeptide Y neurons.
Zhang Y, Shen J, Xie F, Liu Z, Yin F, Cheng M, Wang L, Cai M, Herzog H, Wu P, Zhang Z, et al.
Nature communications (2024) 151: 7603. 135 203 IHC; tested species: mouse
Ebf1 is a mouse deafness gene and deletion causes a dramatic increase in hair cells and support cells of the organ of Corti.
Powers KG, Wilkerson BA, Beach K, Seo SS, Rodriguez JS, Baxter AN, Hunter SE, Bermingham-McDonogh O
Development (Cambridge, England) (2024) : . 135 203 IHC; tested species: mouse
The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, Zimmermann J, Henrion A, Mansouri-Guilani N, Mounier C, Ribeiro S, et al.
Nature communications (2024) 151: 5691. 135 203 ICC, IHC; tested species: mouse
The Role of Vesicular Glutamate Transporter Type 3 in Social Behavior, with a Focus on the Median Raphe Region.
Fazekas CL, Török B, Correia P, Chaves T, Bellardie M, Sipos E, Horváth HR, Gaszner B, Dóra F, Dobolyi Á, Zelena D, et al.
eNeuro (2024) 116: . 135 203 IHC; tested species: mouse
EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.
Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2024) 447: . 135 203 IHC; tested species: mouse
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell.
Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H
Molecular & cellular proteomics : MCP (2023) : 100704. 135 203 IHC; tested species: mouse
In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2.
Li X, Ren M, Gu Y, Zhu T, Zhang Y, Li J, Li C, Wang G, Song L, Bi Z, Liu Z, et al.
Development (Cambridge, England) (2023) 15024: . 135 203 IHC; tested species: mouse
Interrelationships Between Spinal Sympathetic Preganglionic Neurons, Autonomic Systems and Electrical Synapses Formed by Connexin36-containing Gap Junctions.
Recabal-Beyer A, Tavakoli H, Senecal JMM, Stecina K, Nagy JI
Neuroscience (2023) 523: 31-46. 135 203 IHC; tested species: mouse
A glutamatergic DRN-VTA pathway modulates neuropathic pain and comorbid anhedonia-like behavior in mice.
Wang XY, Jia WB, Xu X, Chen R, Wang LB, Su XJ, Xu PF, Liu XQ, Wen J, Song XY, Liu YY, et al.
Nature communications (2023) 141: 5124. 135 203 IHC; tested species: mouse
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain.
Yousefpour N, Locke S, Deamond H, Wang C, Marques L, St-Louis M, Ouellette J, Khoutorsky A, De Koninck Y, Ribeiro-da-Silva A
Cell reports (2023) 421: 112010. 135 203 IHC; tested species: mouse
A New Player in the Hippocampus: A Review on VGLUT3+ Neurons and Their Role in the Regulation of Hippocampal Activity and Behaviour.
Fazekas CL, Szabó A, Török B, Bánrévi K, Correia P, Chaves T, Daumas S, Zelena D
International journal of molecular sciences (2022) 232: . 135 203 IHC; tested species: mouse
Disruption of the grid cell network in a mouse model of early Alzheimer's disease.
Ying J, Keinath AT, Lavoie R, Vigneault E, El Mestikawy S, Brandon MP
Nature communications (2022) 131: 886. 135 203 IHC; tested species: mouse
Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea.
Marchetta P, Eckert P, Lukowski R, Ruth P, Singer W, Rüttiger L, Knipper M
iScience (2022) 253: 103981. 135 203 IHC; tested species: mouse
Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals.
Iyer AA, Hosamani I, Nguyen JD, Cai T, Singh S, McGovern MM, Beyer L, Zhang H, Jen HI, Yousaf R, Birol O, et al.
eLife (2022) 11: . 135 203 IHC; tested species: mouse
Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles.
Cristofari P, Desplanque M, Poirel O, Hébert A, Dumas S, Herzog E, Danglot L, Geny D, Gilles JF, Geeverding A, Bolte S, et al.
Frontiers in molecular neuroscience (2022) 15: 991732. 135 203 IHC; tested species: mouse
Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells.
Heuermann ML, Matos S, Hamilton D, Cox BC
Frontiers in cellular neuroscience (2022) 16: 841864. 135 203 IHC; tested species: mouse
Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors.
Seigneur E, Wang J, Dai J, Polepalli J, Südhof TC
Molecular psychiatry (2021) : . 135 203 IHC; tested species: mouse
A high-density narrow-field inhibitory retinal interneuron with direct coupling to Müller glia.
Grimes WN, Aytürk DG, Hoon M, Yoshimatsu T, Gamlin C, Carrera D, Nath A, Nadal-Nicolás FM, Ahlquist RM, Sabnis A, Berson DM, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) : . 135 203 IHC; tested species: mouse
Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells.
Sun S, Li S, Luo Z, Ren M, He S, Wang G, Liu Z
eLife (2021) 10: . 135 203 IHC; tested species: mouse
Neuronal Dystroglycan regulates postnatal development of CCK/cannabinoid receptor-1 interneurons.
Miller DS, Wright KM
Neural development (2021) 161: 4. 135 203 IHC; tested species: mouse
Neurochemically and Hodologically Distinct Ascending VGLUT3 versus Serotonin Subsystems Comprise the r2-Pet1 Median Raphe.
Senft RA, Freret ME, Sturrock N, Dymecki SM
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) 4112: 2581-2600. 135 203 IHC; tested species: mouse
Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration.
Udagawa T, Atkinson PJ, Milon B, Abitbol JM, Song Y, Sperber M, Huarcaya Najarro E, Scheibinger M, Elkon R, Hertzano R, Cheng AG, et al.
PLoS biology (2021) 1911: e3001445. 135 203 IHC; tested species: mouse
Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea.
Chen Y, Gu Y, Li Y, Li GL, Chai R, Li W, Li H
Cell reports (2021) 353: 109016. 135 203 IHC; tested species: mouse
MOUSE RETINAL CELL ATLAS: MOLECULAR IDENTIFICATION OF OVER SIXTY AMACRINE CELL TYPES.
Yan W, Laboulaye MA, Tran NM, Whitney IE, Benhar I, Sanes JR
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 135 203 IHC; tested species: mouse
Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons.
Pelkey KA, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, Wester JC, Lai M, Mackenzie-Gray Scott C, Yuan X, Hunt S, et al.
eLife (2020) 9: . 135 203 IHC; tested species: mouse
AP180 promotes release site clearance and clathrin-dependent vesicle reformation in mouse cochlear inner hair cells.
Kroll J, Özçete ÖD, Jung S, Maritzen T, Milosevic I, Wichmann C, Moser T
Journal of cell science (2020) 1332: . 135 203 IHC; tested species: mouse
Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses.
Nakakubo Y, Abe S, Yoshida T, Takami C, Isa M, Wojcik SM, Brose N, Takamori S, Hori T
Cell reports (2020) 327: 108040. 135 203 IHC; tested species: mouse
GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.
Wolter S, Möhrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Krämer M, Feil R, Pilz PKD, Knipper M, Rüttiger L, et al.
Frontiers in neural circuits (2018) 12: 65. 135 203 IHC; tested species: mouse
VGLUT3 gates psychomotor effects induced by amphetamine.
Mansouri-Guilani N, Bernard V, Vigneault E, Vialou V, Daumas S, El Mestikawy S, Gangarossa G
Journal of neurochemistry (2018) : . 135 203 IHC; KD verified; tested species: mouse
Combinatorial effects of Alpha- and Gamma-Protocadherins on neuronal survival and dendritic self-avoidance.
Ing-Esteves S, Kostadinov D, Marocha J, Sing AD, Joseph KS, Laboulaye M, Sanes JR, Lefebvre JL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 135 203 IHC; KO verified; tested species: mouse
Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region.
Sos KE, Mayer MI, Cserép C, Takács FS, Szőnyi A, Freund TF, Nyiri G
Brain structure & function (2017) 2221: 287-299. 135 203 IHC
Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb.
Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K
The Journal of comparative neurology (2017) 5253: 574-591. 135 203 IHC; tested species: mouse
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Michalski N, Goutman JD, Auclair SM, Boutet de Monvel J, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, et al.
eLife (2017) 6: . 135 203 IHC; tested species: mouse
Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.
Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, et al.
The EMBO journal (2015) 3421: 2686-702. 135 203 IHC; tested species: mouse
In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1.
Kuo BR, Baldwin EM, Layman WS, Taketo MM, Zuo J
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3530: 10786-98. 135 203 IHC
In vivo generation of immature inner hair cells in neonatal mouse cochleae by ectopic Atoh1 expression.
Liu Z, Fang J, Dearman J, Zhang L, Zuo J
PloS one (2014) 92: e89377. 135 203 IHC; tested species: mouse
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 343: 705-16. 135 203 IHC; tested species: mouse
A new probe for super-resolution imaging of membranes elucidates trafficking pathways.
Revelo NH, Kamin D, Truckenbrodt S, Wong AB, Reuter-Jessen K, Reisinger E, Moser T, Rizzoli SO
The Journal of cell biology (2014) 2054: 591-606. 135 203 IHC
Runx1 controls terminal morphology and mechanosensitivity of VGLUT3-expressing C-mechanoreceptors.
Lou S, Duan B, Vong L, Lowell BB, Ma Q
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 333: 870-82. 135 203 IHC; tested species: mouse
Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.
Li D, Hérault K, Silm K, Evrard A, Wojcik S, Oheim M, Herzog E, Ropert N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3310: 4434-55. 135 203 WB, IHC; KO verified; tested species: mouse
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.
Schallier A, Smolders I, Van Dam D, Loyens E, De Deyn PP, Michotte A, Michotte Y, Massie A
Journal of Alzheimer's disease : JAD (2011) 242: 287-300. 135 203 WB, IHC; KO verified; tested species: mouse
Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.
Reisinger E, Bresee C, Neef J, Nair R, Reuter K, Bulankina A, Nouvian R, Koch M, Bückers J, Kastrup L, Roux I, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3113: 4886-95. 135 203 IHC; tested species: mouse
Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.
Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, et al.
PLoS biology (2011) 94: e1001048. 135 203 IHC; tested species: mouse
Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia.
Sánchez-Mendoza E, Burguete MC, Castelló-Ruiz M, González MP, Roncero C, Salom JB, Arce C, Cañadas S, Torregrosa G, Alborch E, Oset-Gasque MJ, et al.
Journal of neurochemistry (2010) 1135: 1343-55. 135 203 IHC, WB; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 135 203 IHC; tested species: rat
Spatial proteomics in neurons at single-protein resolution.
Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, Marr C, et al.
Cell (2024) 1877: 1785-1800.e16. 135 203 DNA-PAINT; tested species: rat
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3.
Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, et al.
Neuron (2022) : . 135 203 UPTAKE; tested species: rat
Cat. No.: 135 203
Amount: 50 µg
Price: $400.00
Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia.
Tassone A, Martella G, Meringolo M, Vanni V, Sciamanna G, Ponterio G, Imbriani P, Bonsi P, Pisani A
Movement disorders : official journal of the Movement Disorder Society (2021) : . 135 203 WB; tested species: mouse
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 203 WB, ICC; tested species: human,mouse
Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells.
Sánchez-Mendoza EH, Bellver-Landete V, Arce C, Doeppner TR, Hermann DM, Oset-Gasque MJ
PloS one (2017) 125: e0177069. 135 203 WB, ICC
A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes.
Wolfes AC, Ahmed S, Awasthi A, Stahlberg MA, Rajput A, Magruder DS, Bonn S, Dean C
The Journal of general physiology (2017) 1491: 149-170. 135 203 WB
Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.
Li D, Hérault K, Silm K, Evrard A, Wojcik S, Oheim M, Herzog E, Ropert N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3310: 4434-55. 135 203 WB, IHC; KO verified; tested species: mouse
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.
Schallier A, Smolders I, Van Dam D, Loyens E, De Deyn PP, Michotte A, Michotte Y, Massie A
Journal of Alzheimer's disease : JAD (2011) 242: 287-300. 135 203 WB, IHC; KO verified; tested species: mouse
Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.
De Bundel D, Schallier A, Loyens E, Fernando R, Miyashita H, Van Liefferinge J, Vermoesen K, Bannai S, Sato H, Michotte Y, Smolders I, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5792-803. 135 203 WB; tested species: mouse
Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia.
Sánchez-Mendoza E, Burguete MC, Castelló-Ruiz M, González MP, Roncero C, Salom JB, Arce C, Cañadas S, Torregrosa G, Alborch E, Oset-Gasque MJ, et al.
Journal of neurochemistry (2010) 1135: 1343-55. 135 203 IHC, WB; tested species: rat
An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size.
Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N, Rosenmund C
Proceedings of the National Academy of Sciences of the United States of America (2004) 10118: 7158-63. 135 203 WB; tested species: mouse
The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, Zimmermann J, Henrion A, Mansouri-Guilani N, Mounier C, Ribeiro S, et al.
Nature communications (2024) 151: 5691. 135 203 ICC, IHC; tested species: mouse
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model.
Rickner HD, Jiang L, Hong R, O'Neill NK, Mojica CA, Snyder BJ, Zhang L, Shaw D, Medalla M, Wolozin B, Cheng CS, et al.
Nature communications (2022) 131: 6275. 135 203 ICC; tested species: human
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G
Cell reports (2021) 342: 108623. 135 203 WB, ICC; tested species: human,mouse
Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells.
Sánchez-Mendoza EH, Bellver-Landete V, Arce C, Doeppner TR, Hermann DM, Oset-Gasque MJ
PloS one (2017) 125: e0177069. 135 203 WB, ICC
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice.
Herzog E, Nadrigny F, Silm K, Biesemann C, Helling I, Bersot T, Steffens H, Schwartzmann R, Nägerl UV, El Mestikawy S, Rhee J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3143: 15544-59. 135 203 ICC; tested species: mouse
A hybridization-chain-reaction-based method for amplifying immunosignals.
Lin R, Feng Q, Li P, Zhou P, Wang R, Liu Z, Wang Z, Qi X, Tang N, Shao F, Luo M, et al.
Nature methods (2018) 154: 275-278. 135 203 IHC; tested species: mouse
Feedforward inhibition of stress by brainstem neuropeptide Y neurons.
Zhang Y, Shen J, Xie F, Liu Z, Yin F, Cheng M, Wang L, Cai M, Herzog H, Wu P, Zhang Z, et al.
Nature communications (2024) 151: 7603. 135 203 IHC; tested species: mouse
Ebf1 is a mouse deafness gene and deletion causes a dramatic increase in hair cells and support cells of the organ of Corti.
Powers KG, Wilkerson BA, Beach K, Seo SS, Rodriguez JS, Baxter AN, Hunter SE, Bermingham-McDonogh O
Development (Cambridge, England) (2024) : . 135 203 IHC; tested species: mouse
The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, Zimmermann J, Henrion A, Mansouri-Guilani N, Mounier C, Ribeiro S, et al.
Nature communications (2024) 151: 5691. 135 203 ICC, IHC; tested species: mouse
The Role of Vesicular Glutamate Transporter Type 3 in Social Behavior, with a Focus on the Median Raphe Region.
Fazekas CL, Török B, Correia P, Chaves T, Bellardie M, Sipos E, Horváth HR, Gaszner B, Dóra F, Dobolyi Á, Zelena D, et al.
eNeuro (2024) 116: . 135 203 IHC; tested species: mouse
EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.
Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2024) 447: . 135 203 IHC; tested species: mouse
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell.
Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H
Molecular & cellular proteomics : MCP (2023) : 100704. 135 203 IHC; tested species: mouse
In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2.
Li X, Ren M, Gu Y, Zhu T, Zhang Y, Li J, Li C, Wang G, Song L, Bi Z, Liu Z, et al.
Development (Cambridge, England) (2023) 15024: . 135 203 IHC; tested species: mouse
Interrelationships Between Spinal Sympathetic Preganglionic Neurons, Autonomic Systems and Electrical Synapses Formed by Connexin36-containing Gap Junctions.
Recabal-Beyer A, Tavakoli H, Senecal JMM, Stecina K, Nagy JI
Neuroscience (2023) 523: 31-46. 135 203 IHC; tested species: mouse
A glutamatergic DRN-VTA pathway modulates neuropathic pain and comorbid anhedonia-like behavior in mice.
Wang XY, Jia WB, Xu X, Chen R, Wang LB, Su XJ, Xu PF, Liu XQ, Wen J, Song XY, Liu YY, et al.
Nature communications (2023) 141: 5124. 135 203 IHC; tested species: mouse
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain.
Yousefpour N, Locke S, Deamond H, Wang C, Marques L, St-Louis M, Ouellette J, Khoutorsky A, De Koninck Y, Ribeiro-da-Silva A
Cell reports (2023) 421: 112010. 135 203 IHC; tested species: mouse
A New Player in the Hippocampus: A Review on VGLUT3+ Neurons and Their Role in the Regulation of Hippocampal Activity and Behaviour.
Fazekas CL, Szabó A, Török B, Bánrévi K, Correia P, Chaves T, Daumas S, Zelena D
International journal of molecular sciences (2022) 232: . 135 203 IHC; tested species: mouse
Disruption of the grid cell network in a mouse model of early Alzheimer's disease.
Ying J, Keinath AT, Lavoie R, Vigneault E, El Mestikawy S, Brandon MP
Nature communications (2022) 131: 886. 135 203 IHC; tested species: mouse
Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea.
Marchetta P, Eckert P, Lukowski R, Ruth P, Singer W, Rüttiger L, Knipper M
iScience (2022) 253: 103981. 135 203 IHC; tested species: mouse
Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals.
Iyer AA, Hosamani I, Nguyen JD, Cai T, Singh S, McGovern MM, Beyer L, Zhang H, Jen HI, Yousaf R, Birol O, et al.
eLife (2022) 11: . 135 203 IHC; tested species: mouse
Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles.
Cristofari P, Desplanque M, Poirel O, Hébert A, Dumas S, Herzog E, Danglot L, Geny D, Gilles JF, Geeverding A, Bolte S, et al.
Frontiers in molecular neuroscience (2022) 15: 991732. 135 203 IHC; tested species: mouse
Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells.
Heuermann ML, Matos S, Hamilton D, Cox BC
Frontiers in cellular neuroscience (2022) 16: 841864. 135 203 IHC; tested species: mouse
Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors.
Seigneur E, Wang J, Dai J, Polepalli J, Südhof TC
Molecular psychiatry (2021) : . 135 203 IHC; tested species: mouse
A high-density narrow-field inhibitory retinal interneuron with direct coupling to Müller glia.
Grimes WN, Aytürk DG, Hoon M, Yoshimatsu T, Gamlin C, Carrera D, Nath A, Nadal-Nicolás FM, Ahlquist RM, Sabnis A, Berson DM, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) : . 135 203 IHC; tested species: mouse
Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells.
Sun S, Li S, Luo Z, Ren M, He S, Wang G, Liu Z
eLife (2021) 10: . 135 203 IHC; tested species: mouse
Neuronal Dystroglycan regulates postnatal development of CCK/cannabinoid receptor-1 interneurons.
Miller DS, Wright KM
Neural development (2021) 161: 4. 135 203 IHC; tested species: mouse
Neurochemically and Hodologically Distinct Ascending VGLUT3 versus Serotonin Subsystems Comprise the r2-Pet1 Median Raphe.
Senft RA, Freret ME, Sturrock N, Dymecki SM
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) 4112: 2581-2600. 135 203 IHC; tested species: mouse
Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration.
Udagawa T, Atkinson PJ, Milon B, Abitbol JM, Song Y, Sperber M, Huarcaya Najarro E, Scheibinger M, Elkon R, Hertzano R, Cheng AG, et al.
PLoS biology (2021) 1911: e3001445. 135 203 IHC; tested species: mouse
Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea.
Chen Y, Gu Y, Li Y, Li GL, Chai R, Li W, Li H
Cell reports (2021) 353: 109016. 135 203 IHC; tested species: mouse
MOUSE RETINAL CELL ATLAS: MOLECULAR IDENTIFICATION OF OVER SIXTY AMACRINE CELL TYPES.
Yan W, Laboulaye MA, Tran NM, Whitney IE, Benhar I, Sanes JR
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 135 203 IHC; tested species: mouse
Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons.
Pelkey KA, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, Wester JC, Lai M, Mackenzie-Gray Scott C, Yuan X, Hunt S, et al.
eLife (2020) 9: . 135 203 IHC; tested species: mouse
AP180 promotes release site clearance and clathrin-dependent vesicle reformation in mouse cochlear inner hair cells.
Kroll J, Özçete ÖD, Jung S, Maritzen T, Milosevic I, Wichmann C, Moser T
Journal of cell science (2020) 1332: . 135 203 IHC; tested species: mouse
Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses.
Nakakubo Y, Abe S, Yoshida T, Takami C, Isa M, Wojcik SM, Brose N, Takamori S, Hori T
Cell reports (2020) 327: 108040. 135 203 IHC; tested species: mouse
GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.
Wolter S, Möhrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Krämer M, Feil R, Pilz PKD, Knipper M, Rüttiger L, et al.
Frontiers in neural circuits (2018) 12: 65. 135 203 IHC; tested species: mouse
VGLUT3 gates psychomotor effects induced by amphetamine.
Mansouri-Guilani N, Bernard V, Vigneault E, Vialou V, Daumas S, El Mestikawy S, Gangarossa G
Journal of neurochemistry (2018) : . 135 203 IHC; KD verified; tested species: mouse
Combinatorial effects of Alpha- and Gamma-Protocadherins on neuronal survival and dendritic self-avoidance.
Ing-Esteves S, Kostadinov D, Marocha J, Sing AD, Joseph KS, Laboulaye M, Sanes JR, Lefebvre JL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) : . 135 203 IHC; KO verified; tested species: mouse
Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region.
Sos KE, Mayer MI, Cserép C, Takács FS, Szőnyi A, Freund TF, Nyiri G
Brain structure & function (2017) 2221: 287-299. 135 203 IHC
Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb.
Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K
The Journal of comparative neurology (2017) 5253: 574-591. 135 203 IHC; tested species: mouse
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Michalski N, Goutman JD, Auclair SM, Boutet de Monvel J, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, et al.
eLife (2017) 6: . 135 203 IHC; tested species: mouse
Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.
Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, et al.
The EMBO journal (2015) 3421: 2686-702. 135 203 IHC; tested species: mouse
In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1.
Kuo BR, Baldwin EM, Layman WS, Taketo MM, Zuo J
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3530: 10786-98. 135 203 IHC
In vivo generation of immature inner hair cells in neonatal mouse cochleae by ectopic Atoh1 expression.
Liu Z, Fang J, Dearman J, Zhang L, Zuo J
PloS one (2014) 92: e89377. 135 203 IHC; tested species: mouse
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 343: 705-16. 135 203 IHC; tested species: mouse
A new probe for super-resolution imaging of membranes elucidates trafficking pathways.
Revelo NH, Kamin D, Truckenbrodt S, Wong AB, Reuter-Jessen K, Reisinger E, Moser T, Rizzoli SO
The Journal of cell biology (2014) 2054: 591-606. 135 203 IHC
Runx1 controls terminal morphology and mechanosensitivity of VGLUT3-expressing C-mechanoreceptors.
Lou S, Duan B, Vong L, Lowell BB, Ma Q
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 333: 870-82. 135 203 IHC; tested species: mouse
Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.
Li D, Hérault K, Silm K, Evrard A, Wojcik S, Oheim M, Herzog E, Ropert N
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3310: 4434-55. 135 203 WB, IHC; KO verified; tested species: mouse
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.
Schallier A, Smolders I, Van Dam D, Loyens E, De Deyn PP, Michotte A, Michotte Y, Massie A
Journal of Alzheimer's disease : JAD (2011) 242: 287-300. 135 203 WB, IHC; KO verified; tested species: mouse
Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.
Reisinger E, Bresee C, Neef J, Nair R, Reuter K, Bulankina A, Nouvian R, Koch M, Bückers J, Kastrup L, Roux I, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3113: 4886-95. 135 203 IHC; tested species: mouse
Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.
Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, et al.
PLoS biology (2011) 94: e1001048. 135 203 IHC; tested species: mouse
Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia.
Sánchez-Mendoza E, Burguete MC, Castelló-Ruiz M, González MP, Roncero C, Salom JB, Arce C, Cañadas S, Torregrosa G, Alborch E, Oset-Gasque MJ, et al.
Journal of neurochemistry (2010) 1135: 1343-55. 135 203 IHC, WB; tested species: rat
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro () 61: . 135 203 IHC; tested species: rat
Spatial proteomics in neurons at single-protein resolution.
Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, Marr C, et al.
Cell (2024) 1877: 1785-1800.e16. 135 203 DNA-PAINT; tested species: rat
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3.
Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, et al.
Neuron (2022) : . 135 203 UPTAKE; tested species: rat
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Background

The vesicular glutamate transporter 3 VGLUT 3 is closely related to VGLUT 1 and VGLUT 2 by sequence similarity. However, VGLUT 3 defines a new distinct glutamatergic system in brain which is strictly seperated from VGLUT 1 and VGLUT 2 synapses. Co-localization with the acetylcholine transporter VAChT and the monoamine transporter 2 VMaT 2 has been observed.
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