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Neuroligin3 antibody - 129 321 K.O.

Neuroligins are postsynaptic cell adhesion molecules
Mouse monoclonal purified IgG
Cat. No.: 129 321
Amount: 100 µg
Price: $415.00
Cat. No. 129 321 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: 1 : 1000 (AP-staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 100 gallery  
Clone SY-112A8
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to residues near the carboxy terminus of mouse Neuroligin 3 (UniProt Id: Q8BYM5)
Reactivity Reacts with: mouse (Q8BYM5), rat (Q62889).
Other species not tested yet.
Specificity K.O. validated
Data sheet 129_321.pdf
Cat. No.: 129 321
Amount: 100 µg
Price: $415.00

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.