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Neuroligin3 protein - 129-1P

Neuroligins are postsynaptic cell adhesion molecules
control protein
Cat. No.: 129-1P
Amount: 100 µg
Price: $105.00
Cat. No. 129-1P 100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use.
Control proteins should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
Immunogen Recombinant protein corresponding to AA 710 to 824 from mouse Neuroligin3 (UniProt Id: Q8BYM5)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 129 103, 129 211, 129 311
Remarks

This control protein consists of the recombinant protein (aa 710-824 of mouse neuroligin 3) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 129-1p.pdf
Cat. No.: 129-1P
Amount: 100 µg
Price: $105.00
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.

Protocols