Synaptic Systems - Complexin1/2

Cat. No.: 122 003

Amount: 50 µg

Price: $460.00

Cat. No. 122 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 (AP staining) gallery IP: not tested yet ICC: 1 : 500 gallery IHC: 1 : 200 up to 1 : 500 gallery IHC-P: not tested yet
Immunogen	Synthetic peptide corresponding to AA 122 to 134 from human Complexin2 (UniProt Id: Q6PUV4)
Reactivity	Reacts with: rat (P63041, P84087), mouse (P63040, P84086), human (O14810, Q6PUV4), cow, electric ray, rabbit. Other species not tested yet.
Specificity	Recognizes complexin 1 and 2. K.O. validated
Matching control protein/peptide	122-0P
Data sheet	122_003.pdf

Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease.
Fonseca-Ornelas L, Viennet T, Rovere M, Jiang H, Liu L, Nuber S, Ericsson M, Arthanari H, Selkoe DJ
Cell reports (2021) 361: 109333. 122 003 WB; tested species: mouse

Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4.
Reim K, Regus-Leidig H, Ammermüller J, El-Kordi A, Radyushkin K, Ehrenreich H, Brandstätter JH, Brose N
Journal of cell science (2009) 122Pt 9: 1352-61. 122 003 WB, IHC; tested species: mouse

Cat. No.: 122 003

Amount: 50 µg

Price: $460.00

ICC

IHC

Background

Protocols

Complexin1/2 antibody C-terminus - 122 003 K.O.