Cat. No.: 114 018
Amount: 50 µg
Price:
$415.00
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| Cat. No. 114 018 |
50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | Rb003-102 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Full length native human GluN1 (UniProt Id: Q05586) |
| Reactivity |
Reacts with: mouse (P35438), rat (P35439). Other species not tested yet. |
| Remarks |
This antibody is a chimeric antibody based on the monoclonal human antibody 003-102. The constant regions of the heavy and light chains have been replaced with rabbit specific sequences. The antibody can therefore be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells. |
| Data sheet | 114_018.pdf |
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GluNs (NMDA-receptors) represent a class of glutamate receptors that are of central importance in synaptic plasticity. Multiple NMDA receptor subtypes exist: GluN1 and GluN2 A-D. GluN1 is the most important as it is required for activity. NMDA-receptors allow Ca2+ influx and are thought to trigger Ca2+ dependent postsynaptic processes involved in long term potentiation and depression.