Tailor-made Antibodies
and Tools for Life Science

Synapsin2 antibody - 106 203 K.O.

Synapsins are peripheral synaptic vesicle proteins and substrate for several protein kinases
Rabbit polyclonal purified antibody
Cat. No.: 106 203
Amount: 50 µg
Price: $380.00
Cat. No. 106 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining)
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 200 gallery  
IHC-P: 1 : 200 gallery  
Immunogen Synthetic peptide corresponding to residues surrounding (AA 450) of rat Synapsin2 (UniProt Id: Q63537-1)
Reactivity Reacts with: human (Q92777), rat (Q63537), mouse (Q64332), pig.
Other species not tested yet.
Specificity Specific for synapsins 2a and 2b, no cross-reactivity to synapsin 1a/b. K.O. validated PubMed: 26177381
Matching control protein/peptide 106-2P
Data sheet 106_203.pdf

References for Synapsin2 - 106 203

A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae.
Li R, Zhang L, Shi Q, Guo Y, Zhang W, Zhou B
Aquatic toxicology (Amsterdam, Netherlands) (2018) 199: 46-54. 106 203 WB; tested species: zebrafish
Transgenerational endocrine disruption and neurotoxicity in zebrafish larvae after parental exposure to binary mixtures of decabromodiphenyl ether (BDE-209) and lead.
Chen L, Wang X, Zhang X, Lam PKS, Guo Y, Lam JCW, Zhou B
Environmental pollution (Barking, Essex : 1987) (2017) 230: 96-106. 106 203 WB; tested species: danio rerio
Synapsin IIb as a functional marker of submissive behavior.
Nesher E, Koman I, Gross M, Tikhonov T, Bairachnaya M, Salmon-Divon M, Levin Y, Gerlitz G, Michaelevski I, Yadid G, Pinhasov A, et al.
Scientific reports (2015) 5: 10287. 106 203 WB
Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl CT
PloS one (2015) 107: e0132366. 106 203 WB, IHC; KO verified
Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae.
Chen L, Yu K, Huang C, Yu L, Zhu B, Lam PK, Lam JC, Zhou B
Environmental science & technology (2012) 4617: 9727-34. 106 203 WB
Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.
Inoue D, Kimura I, Wakabayashi M, Tsumoto H, Ozawa K, Hara T, Takei Y, Hirasawa A, Ishihama Y, Tsujimoto G
FEBS letters (2012) 58610: 1547-54. 106 203 WB, IP; tested species: mouse
Cat. No.: 106 203
Amount: 50 µg
Price: $380.00