Cat. No.: 184-0P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 184-0P |
100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use. Control proteins should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
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| Immunogen | Recombinant protein corresponding to AA 1 to 232 from rat Velis1 (UniProt Id: Q9Z250) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Matching antibodies | 184 002, 184 003 |
| Remarks |
This control protein consists of the recombinant full length rat veli 1 that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 184-0p.pdf |
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The complex of the multi-adaptor-proteins CASK, Mint and Veli, also referred to as MALS and Lin 7, is conserved across kingdoms and may be involved in localizing synaptic vesicles at synaptic terminals. Three Veli isoforms (1, 2 and 3) with different expression patterns have been described, so far.
Veli proteins have also been suggested to participate in regulating the recruitment of neurotransmitter receptors to the post synaptic density (PSD) by interaction with their PDZ domains.