VDAC1 peptide - 279-0P

VDAC1 is a pore forming transmembrane protein

control peptide

Cat. No.: 279-0P

Amount: 100 µg

Price: $105.00

Cat. No. 279-0P	100 µg peptide, lyophilized. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized!
Applications
Immunogen	Synthetic peptide corresponding to AA 15 to 29 from mouse VDAC1 (UniProt Id: Q60932-1)
Recommended dilution	Optimal concentrations should be determined by the end-user.
Matching antibodies	279 003
Remarks	This control peptide consists of the synthetic peptide (aa 15-29 of mouse VDAC 1) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet	279-0p.pdf

Cat. No.: 279-0P

Amount: 100 µg

Price: $105.00

Background

Voltage-dependent anion channels (VDACs), also known as porins, are integral membrane proteins which form a channel that allows diffusion of small hydrophilic molecules. Three closely related isoforms, VDAC 1, 2 and 3 have been described, so far.
VDACs have been originally identified as components of the outer mitochondrial membrane but they also occur in the plasma membrane of different cell types.

1 ) Kotake S et al., Cell Biol. Int. (2013)
2 ) Abu-Hamad S et al., Proc. Natl. Acad. Sci. U.S.A. (2006)
3 ) Adachi M et al., Am. J. Physiol. Gastrointest. Liver Physiol. (2004)
4 ) Bahamonde MI et al., Pflugers Arch. (2003)
5 ) Narita M et al., Proc. Natl. Acad. Sci. U.S.A. (1998)
6 ) De Pinto V et al., Biochim. Biophys. Acta (1987)
7 ) Colombini M et al., Ann. N. Y. Acad. Sci. (1980)

Protocols

OTHER

Preadsorbtion

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