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Home > Products > 121 003

SCAMP1 antibody - 121 003

SCAMP 1 is an ubiquitous integral membrane protein of secretory and transport vesicles
Rabbit polyclonal purified antibody
Cat. No.: 121 003
Amount: 50 µg
Price: $455.00
Cat. No. 121 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 2 to 15 from rat SCAMP1 (UniProt Id: P56603)
Reactivity Reacts with: human (O15126), rat (P56603), mouse (Q8K021), hamster.
Other species not tested yet.
Matching control protein/peptide 121-0P
Data sheet 121_003.pdf

References for SCAMP1 - 121 003

Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 121 003 WB; tested species: mouse,rat
Cat. No.: 121 003
Amount: 50 µg
Price: $455.00
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 121 003 WB; tested species: mouse,rat
WB
ICC
IHC
IHC-P
Background
SCAMPs (secretory carrier membrane proteins) are general markers of membranes that function in cell surface recycling such as secretory vesicles, pancreatic granules, etc. They have four conserved transmembrane regions (TMRs) suggesting a "core" function in membrane traffic.
Five isoforms (SCAMP 1-5) have been described. SCAMP 1-3 contain NPF repeats that interact with EH-domain proteins which are involved in the budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMP 4 and SCAMP 5 lack the NPF repeats.
SCAMP 1-4 are ubiquitously expressed whereas SCAMP 5 is expressed exclusively in brain during late development.
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