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Home > Products > 121-0P

SCAMP1 peptide - 121-0P

SCAMP 1 is an ubiquitous integral membrane protein of secretory and transport vesicles
control peptide
Cat. No.: 121-0P
Amount: 100 µg
Price: $105.00
Cat. No. 121-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Applications
 
Immunogen Synthetic peptide corresponding to AA 2 to 15 from rat SCAMP1 (UniProt Id: P56603)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 121 002, 121 003
Remarks

This control peptide consists of the synthetic peptide (SDFDSNPFADPDLN) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet 121-0p.pdf
Cat. No.: 121-0P
Amount: 100 µg
Price: $105.00
Background
SCAMPs (secretory carrier membrane proteins) are general markers of membranes that function in cell surface recycling such as secretory vesicles, pancreatic granules, etc. They have four conserved transmembrane regions (TMRs) suggesting a "core" function in membrane traffic.
Five isoforms (SCAMP 1-5) have been described. SCAMP 1-3 contain NPF repeats that interact with EH-domain proteins which are involved in the budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMP 4 and SCAMP 5 lack the NPF repeats.
SCAMP 1-4 are ubiquitously expressed whereas SCAMP 5 is expressed exclusively in brain during late development.
Protocols
OTHER
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