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PACSIN1 protein - 196-0P

PACSIN1 is a dynamin1 associated protein
control protein
Cat. No.: 196-0P
Amount: 100 µg
Price: $105.00
Cat. No. 196-0P 100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use.
Control proteins should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
Immunogen Recombinant protein corresponding to AA 293 to 384 from mouse PACSIN1 (UniProt Id: Q61644)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 196 002, 196 003
Remarks

This control protein consists of the recombinant protein (aa 293 - 384 of mouse PACSIN 1) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 196-0p.pdf
Cat. No.: 196-0P
Amount: 100 µg
Price: $105.00
Background

This protein has been described as PACSIN 1 (for PKC and CK2 substrate in neurons) and syndapin 1 (synaptic, dynamin-associated protein I). It is a multidomain phospho-protein that interacts via its SH3 domain with dynamin 1, synaptojanin, synapsin and N-WASP. Since N-WASP is an activator of the Arp2/3 complex, syndapin may link membrane trafficking and the actin cytoskeleton.
Up to now, 3 isoforms have been described. Syndapin 1 shows a neuronal, syndapin 3 a muscular and syndapin 2 an ubiquitous expression profile.

Protocols