Cat. No.: 129 403
Amount: 50 µg
Price:
$375.00
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| Cat. No. 129 403 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 686 to 699 from mouse Neuroligin4 (UniProt Id: B0F2B4) |
| Reactivity |
Reacts with: mouse (B0F2B4). No signal: zebrafish, rat. Other species not tested yet. |
| Specificity | K.O. validated |
| Matching control protein/peptide | 129-4P |
| Data sheet | 129_403.pdf |
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Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin1 and neuroligin3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin2 is found exclusively on inhibitory synapses.
Mutations in neuroligin3 and 4 have been implicated with a rare, heritable form of autism.