Cat. No.: 129-4P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 129-4P |
100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized! |
| Applications |
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| Immunogen | Synthetic peptide corresponding to AA 686 to 699 from mouse Neuroligin4 (UniProt Id: B0F2B4) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Matching antibodies | 129 403 |
| Remarks |
This control peptide consists of the synthetic peptide (aa 686-699 of mouse neuroligin 4) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 129-4p.pdf |
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Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and 4 have been implicated with a rare, heritable form of autism.