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Neuroligin4 antibody - 129 403 K.O.

Neuroligins are postsynaptic cell adhesion molecules
Rabbit polyclonal purified antibody
Cat. No.: 129 403
Amount: 50 µg
Price: $375.00
Cat. No. 129 403 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 686 to 699 from mouse Neuroligin4 (UniProt Id: B0F2B4)
Reactivity Reacts with: mouse (B0F2B4).
No signal: zebrafish, rat.
Other species not tested yet.
Specificity K.O. validated
Matching control protein/peptide 129-4P
Data sheet 129_403.pdf

References for Neuroligin4 - 129 403

Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.
Xu ZX, Kim GH, Tan JW, Riso AE, Sun Y, Xu EY, Liao GY, Xu H, Lee SH, Do NY, Lee CH, et al.
Nature communications (2020) 111: 1797. 129 403 WB; tested species: mouse
Cat. No.: 129 403
Amount: 50 µg
Price: $375.00
Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.
Xu ZX, Kim GH, Tan JW, Riso AE, Sun Y, Xu EY, Liao GY, Xu H, Lee SH, Do NY, Lee CH, et al.
Nature communications (2020) 111: 1797. 129 403 WB; tested species: mouse
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and 4 have been implicated with a rare, heritable form of autism.