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MAL2A antibody - 229 003

MAL 2A is a member of the MAL protein family
Rabbit polyclonal purified antibody
Cat. No.: 229 003
Amount: 50 µg
Price: $375.00
Cat. No. 229 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 13 to 21 from rat MAL2A (UniProt Id: Q7TPB7)
Reactivity Reacts with: rat (Q7TPB7).
Other species not tested yet.
Matching control protein/peptide 229-0P
Data sheet 229_003.pdf

References for MAL2A - 229 003

Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Cat. No.: 229 003
Amount: 50 µg
Price: $375.00
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.
Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 301: 2-12. 229 003 WB, ICC, IHC
Background
MAL 2 is an integral membrane protein that contains 4 putative transmembrane domains and belongs to the myelin and lymphocyte (MAL) protein family. Two isoforms, MAL 2A and MAL 2B, have been described so far. MAL 2 overexpression has been reported in several cancer types like breast, ovarian, and pancreatic carcinoma. It has been shown to be an essential component of the machinery for basolateral-to-apical transcytosis in hepatoma HepG2 cells but its mechanistic function still has to be elucidated.
Recently MAL 2A has been identified as a synaptic vesicle protein mainly localized to VGluT positive vesicles.