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GluA3 peptide - 182-2P

GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission
control peptide
Cat. No.: 182-2P
Amount: 100 µg
Price: $105.00
Cat. No. 182-2P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Applications
 
Immunogen Synthetic peptide corresponding to AA 860 to 871 from mouse GluA3 (UniProt Id: Q9Z2W9)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 182 203
Remarks

This control peptide consists of the synthetic peptide (aa 860 - 871 in mouse GluA 3) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 182-2p.pdf
Cat. No.: 182-2P
Amount: 100 µg
Price: $105.00
Background

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.

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