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Home > Products > 182 203

GluA3 antibody - 182 203

GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission
Rabbit polyclonal purified antibody
Cat. No.: 182 203
Amount: 50 µg
Price: $375.00
Cat. No. 182 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 860 to 871 from mouse GluA3 (UniProt Id: Q9Z2W9)
Reactivity Reacts with: human (P42263), rat (P19492), mouse (Q9Z2W9), pig, cow.
No signal: zebrafish.
Other species not tested yet.
Matching control protein/peptide 182-2P
Data sheet 182_203.pdf

References for GluA3 - 182 203

Chronic mild corticosterone exposure during adolescence enhances behaviors and upregulates neuroplasticity-related proteins in rat hippocampus.
Li J, Li Y, Sun Y, Wang H, Liu X, Zhao Y, Wang H, Su Y, Si T
Progress in neuro-psychopharmacology & biological psychiatry (2019) 89: 400-411. 182 203 WB; tested species: rat
Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.
Sultana A, Nakaya N, Dong L, Abu-Asab M, Qian H, Tomarev SI
Experimental neurology (2014) 261: 802-11. 182 203 WB
Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.
Nakaya N, Sultana A, Munasinghe J, Cheng A, Mattson MP, Tomarev SI
Experimental neurology (2013) 250: 205-18. 182 203 WB; tested species: mouse
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, et al.
Nature (2012) 4867402: 256-60. 182 203 WB
GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites.
Perozzo AM, Schwenk J, Kamalova A, Nakagawa T, Fakler B, Bowie D
Nature communications (2023) 141: 6799. 182 203 IP; tested species: rat
AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.
Brechet A, Buchert R, Schwenk J, Boudkkazi S, Zolles G, Siquier-Pernet K, Schaber I, Bildl W, Saadi A, Bole-Feysot C, Nitschke P, et al.
Nature communications (2017) 8: 15910. 182 203 IP; tested species: mouse
High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.
Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Müller CS, Bildl W, Baehrens D, Hüber B, Kulik A, Klöcker N, et al.
Neuron (2012) 744: 621-33. 182 203 IP; tested species: rat
Molecular Characterization of AMPA-Receptor-Containing Vesicles.
Peters JJ, Leitz J, Oses-Prieto JA, Burlingame AL, Brunger AT
Frontiers in molecular neuroscience (2021) 14: 754631. 182 203 EM; tested species: mouse
Cat. No.: 182 203
Amount: 50 µg
Price: $375.00
Chronic mild corticosterone exposure during adolescence enhances behaviors and upregulates neuroplasticity-related proteins in rat hippocampus.
Li J, Li Y, Sun Y, Wang H, Liu X, Zhao Y, Wang H, Su Y, Si T
Progress in neuro-psychopharmacology & biological psychiatry (2019) 89: 400-411. 182 203 WB; tested species: rat
Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.
Sultana A, Nakaya N, Dong L, Abu-Asab M, Qian H, Tomarev SI
Experimental neurology (2014) 261: 802-11. 182 203 WB
Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.
Nakaya N, Sultana A, Munasinghe J, Cheng A, Mattson MP, Tomarev SI
Experimental neurology (2013) 250: 205-18. 182 203 WB; tested species: mouse
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, et al.
Nature (2012) 4867402: 256-60. 182 203 WB
GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites.
Perozzo AM, Schwenk J, Kamalova A, Nakagawa T, Fakler B, Bowie D
Nature communications (2023) 141: 6799. 182 203 IP; tested species: rat
AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.
Brechet A, Buchert R, Schwenk J, Boudkkazi S, Zolles G, Siquier-Pernet K, Schaber I, Bildl W, Saadi A, Bole-Feysot C, Nitschke P, et al.
Nature communications (2017) 8: 15910. 182 203 IP; tested species: mouse
High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.
Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Müller CS, Bildl W, Baehrens D, Hüber B, Kulik A, Klöcker N, et al.
Neuron (2012) 744: 621-33. 182 203 IP; tested species: rat
Molecular Characterization of AMPA-Receptor-Containing Vesicles.
Peters JJ, Leitz J, Oses-Prieto JA, Burlingame AL, Brunger AT
Frontiers in molecular neuroscience (2021) 14: 754631. 182 203 EM; tested species: mouse
WB
Background

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.
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