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Home > Products > 377 006
- will be discontinued soon
Polyclonal antibodies are a finite resource. We have now started to sell the last lots of our well received chicken polyclonal TRIM46 antibody 377 006.

TRIM46 antibody - 377 006

TRIM46 is involved in establishing neuronal polarity
Chicken polyclonal purified antibody
Cat. No.: 377 006
Amount: 50 µg
Price: $380.00
Cat. No. 377 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC-P: not recommended
Immunogen Recombinant protein corresponding to AA 1 to 561 from rat Trim46 (UniProt Id: A0A0G2JXN2)
Reactivity Reacts with: rat (A0A0G2JXN2), mouse (Q7TNM2).
Other species not tested yet.
Remarks

IHC: Antigen retrieval (10mM citrate, pH 6.0, overnight at 60°C) is recommended.
Data sheet 377_006.pdf

References for TRIM46 - 377 006

Immunoproximity biotinylation reveals the axon initial segment proteome.
Zhang W, Fu Y, Peng L, Ogawa Y, Ding X, Rasband A, Zhou X, Shelly M, Rasband MN, Zou P
Nature communications (2023) 141: 8201. 377 006 ICC; tested species: rat
Cat. No.: 377 006
Amount: 50 µg
Price: $380.00
Immunoproximity biotinylation reveals the axon initial segment proteome.
Zhang W, Fu Y, Peng L, Ogawa Y, Ding X, Rasband A, Zhou X, Shelly M, Rasband MN, Zou P
Nature communications (2023) 141: 8201. 377 006 ICC; tested species: rat
ICC
ICC
IHC
IHC
Background
The tripartite motif containing protein TRIM 46, also referred to as TRIFIC, is a member of the C-I TRIM family, a subfamily of the RBCC (N-terminal RING finger/B-box/coiled coil)/TRIM superfamily.
TRIM 46 localizes to newly specified axons and, at later stages, to the axon initial segment (AIS). By forming closely spaced parallel microtubule bundles it plays a crucial role in the initial polarization of neuronal cells.
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