Cat. No. 377 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications | |
Immunogen | Recombinant protein comprising a major part of the protein (UniProt Id: A0A0G2JXN2) |
Reactivity |
Reacts with: rat (A0A0G2JXN2), mouse (Q7TNM2). Other species not tested yet. |
Remarks |
IHC: For optimal signal to noise ratio, we recommend our recombinant rabbit TRIM46 antibody 377 008 |
Data sheet | 377_003.pdf |
The tripartite motif containing protein TRIM46, also referred to as TRIFIC, is a member of the C-I TRIM family, a subfamily of the RBCC (N-terminal RING finger/B-box/coiled coil)/TRIM superfamily.
TRIM46 localizes to newly specified axons and, at later stages, to the axon initial segment (AIS). By forming closely spaced parallel microtubule bundles it plays a crucial role in the initial polarization of neuronal cells.