Cat. No.: 377 008
Amount: 50 µg
Price:
$415.00
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| Cat. No. 377 008 |
50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | Rb264D12 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Recombinant protein comprising a major part of the protein (UniProt Id: A0A0G2JXN2) |
| Epitop |
AA 1 to 114 from rat Trim46 (UniProt Id: A0A0G2JXN2) |
| Reactivity |
Reacts with: mouse (Q7TNM2), rat (A0A0G2JXN2). Other species not tested yet. |
| Specificity | K.O. validated |
| Remarks |
This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 264D12. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells. |
| Data sheet | 377_008.pdf |
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The tripartite motif containing protein TRIM46, also referred to as TRIFIC, is a member of the C-I TRIM family, a subfamily of the RBCC (N-terminal RING finger/B-box/coiled coil)/TRIM superfamily.
TRIM46 localizes to newly specified axons and, at later stages, to the axon initial segment (AIS). By forming closely spaced parallel microtubule bundles it plays a crucial role in the initial polarization of neuronal cells.