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Rab 7a antibody - 320 003

Rab7a is a key regulator in endo-lysosomal trafficking
Polyclonal rabbit purified antibody
Cat. No.: 320 003
Amount: 50 µg
Price: $370.00
Cat. No. 320 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 185 to 205 from mouse Rab7a (UniProt Id: P51150)
Reactivity Reacts with: human (P51149), rat (P09527), mouse (P51150).
Other species not tested yet.
Specificity Specific for rab 7a.
Matching control protein/peptide 320-0P
Data sheet 320_003.pdf

References for Rab 7a - 320 003

VAPB depletion alters neuritogenesis and phosphoinositide balance in motoneuron-like cells: relevance to VAPB-linked ALS.
Genevini P, Colombo MN, Venditti R, Marcuzzo S, Colombo SF, Bernasconi P, De Matteis MA, Borgese N, Navone F
Journal of cell science (2019) : . 320 003 WB; tested species: mouse
EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons.
Burk K, Murdoch JD, Freytag S, Koenig M, Bharat V, Markworth R, Burkhardt S, Fischer A, Dean C
Scientific reports (2017) 71: 2149. 320 003 ICC; tested species: mouse
Cat. No.: 320 003
Quantity: 50 µg
Price: $370.00
VAPB depletion alters neuritogenesis and phosphoinositide balance in motoneuron-like cells: relevance to VAPB-linked ALS.
Genevini P, Colombo MN, Venditti R, Marcuzzo S, Colombo SF, Bernasconi P, De Matteis MA, Borgese N, Navone F
Journal of cell science (2019) : . 320 003 WB; tested species: mouse
EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons.
Burk K, Murdoch JD, Freytag S, Koenig M, Bharat V, Markworth R, Burkhardt S, Fischer A, Dean C
Scientific reports (2017) 71: 2149. 320 003 ICC; tested species: mouse
Background
Rab 7 is a member of the Rab protein family that belongs to the ras-related superfamily of small monomeric GTPases. Rab 7 is ubiquitously expressed in different tissues where it controls membrane trafficking from early to late endosome and to lysosomes. Rab 7 is also involved in the maturation of phagosome and autophagic vacuoles.