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Cre-Recombinase antibody - 257 004

Cre-recombinase is used for conditional or tissue specific knockouts
Guinea pig polyclonal antiserum
Cat. No.: 257 004
Amount: 100 µl
Price: $375.00
Cat. No. 257 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications
 
WB: not tested yet
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 343 from Bacteriophage P1 Cre-Recombinase (UniProt Id: P06956)
Specificity Recognizes Cre- and iCre-recombinase.
Data sheet 257_004.pdf

References for Cre-Recombinase - 257 004

Striatal Direct Pathway Targets Npas1+ Pallidal Neurons.
Cui Q, Du X, Chang IYM, Pamukcu A, Lilascharoen V, Berceau BL, García D, Hong D, Chon U, Narayanan A, Kim Y, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) 4118: 3966-3987. 257 004 IHC; tested species: mouse
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices.
Imig C, López-Murcia FJ, Maus L, García-Plaza IH, Mortensen LS, Schwark M, Schwarze V, Angibaud J, Nägerl UV, Taschenberger H, Brose N, et al.
Neuron (2020) : . 257 004 IHC; tested species: mouse
Cat. No.: 257 004
Amount: 100 µl
Price: $375.00
Striatal Direct Pathway Targets Npas1+ Pallidal Neurons.
Cui Q, Du X, Chang IYM, Pamukcu A, Lilascharoen V, Berceau BL, García D, Hong D, Chon U, Narayanan A, Kim Y, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) 4118: 3966-3987. 257 004 IHC; tested species: mouse
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices.
Imig C, López-Murcia FJ, Maus L, García-Plaza IH, Mortensen LS, Schwark M, Schwarze V, Angibaud J, Nägerl UV, Taschenberger H, Brose N, et al.
Neuron (2020) : . 257 004 IHC; tested species: mouse
Background
Cre-Recombinase is a 38 kDa type 1 topoisomerase from bacteriophage P1. It is highly specific for a 34 bp DNA sequence (loxP) found in P1 DNA and catalyzes site-specific recombination between two 34-base-pair LOXP recognition sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. Its highly specific catalytic activity makes it a valuable tool for the generation of conditional or tissue specific mutants.